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IMPORTANCE
One:
0
1
Prevention of obesity in children and adults is a public health imperative because it
is associated with significant health burdens
Two:
0
2
Infancy may be a critical period when environmental factors exert a lasting effect on
risk for obesity; identifying modifiable risk factors may help reduce this risk
Three:
0
3 There is a need to determine the influence of antibiotic use on early childhood obesity
given the large shifts in diet and environmental contacts in infancy, the national
burden of disease, and ample opportunity for improved antimicrobial use
Why the research was done
IMPORTANCE
OBJECTIVE
6399 (9%):
73024 (88%) Excluded for lacking
With recurring visit at age 24-59mo
visits
26
26
15-19 11-14
AT PRIMARY CARE VISITS (MO.) CALENDAR YEAR OF FIRST VISIT INSURANCE COVERAGE
11669
<1 11144 11170 Private Public
10315 10689
77
41
5619
10 - 12 5 58
7 - 96 2007
2661
6
4-6 5 206 *Other (1%)
1-3 2001 2002 2003 2004 2005 2006 2007 2008 2009 *Self-Pay (<0,1%)
Know what youre talking about
Defining measurements
KEY POINTS
KEY POINTS
No significant association:
Obesity and Narrow Spectrum AB
KEY POINTS
No significant association:
Obesity and Narrow Spectrum AB
DISCUSSION
STEROIDS
2nd most common prescribed medication in this
age group
Effect size similar to frequent antibiotic use
A final review of key points
CONCLUSIONS
Point 1
Point 2
W-W-W-W-W
What Where
An observational cohort study using Primary care practices affiliated with the
electronic health records Childrens Hospital of Philadelphia including
both teaching clinics and private practices in
urban Philadelphia, Pennsylvania, and the
surrounding region
Who
L. Charles Bailey, MD, PhD; Christopher
B. Forrest, MD, PhD; Peixin Zhang, PhD; Why
Thomas M. Richards, MS; Alice Livshits, To assess the impact of antibiotics
BS; Patricia A. DeRusso, MD, MS prescribed in infancy (ages 0-23
When months) on obesity in early
Spanning 2001-2013 childhood (ages 24-59 months)
Published in 2014
TAKE HOME MESSAGE:
DONT GO BROAD IF YOU CAN KEEP IT NARROW