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•This malformation cause the bone marrow to produce fewer cell ,and
sometimes the cells die than the 120 day life expentancy.
•Instead of being round or disc-shaped ,the red blood cells can be oval.
•All cell lines have dyspoiesis ,in which cytoplasmic maturity is greater
than nuclear maturity.
•Because dyspoiesis affects all cell lines ,retilocytopenia and during later
stages leukopenia and thrombocytopenia develop.
• Alcohol abuse.
• Chemotherapy drugs.
•Inherited disorder.
•Myelodysplastic syndrome.
Sign and Symptom
continuous ,the weight loss could After a while ,the condition will begin to
become significant. affect the digestive system and this will
NUMBNESS
Diagnostic Test
A. Complete blood count (FBC ,CBC).
E. Schilling test.
• Injection or tablet of nonradioactive vitamin B12 .
• Then urine sample are collected.
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