Académique Documents
Professionnel Documents
Culture Documents
and Adaptation
Irfannuddin, Hardi Darmawan, Heri Asnawi
Department of Physiology & Biophysic
Block of Homeostatic & Metabolism
Learning Objectives
Adaptive responses
Physiological changes that minimize
bodily strain
The bodys attempt to counteract
stressor and reestablish homeostasis
The return to non stress conditions
reflects improved bodily function in the
involved organ or system
Type of adaptations
1. Accommodation
2. Acclimation & acclimatization
3. Genetic adaptation
1. Accommodation
Intermediate adaptation
Involve a complex array of adaptive
responses
Acclimation
Induced experimentally in an artificial
environment
Example: exercise training
Acclimatization
Induced by exposure of natural environment
Example: adaptation in high altitude
3. Genetic adaptation
Mobilized by :
Central Nervous System (CNS)
Endocrine System
Immune System
Effect to :
All the systems in body
Respond to various stressor in unique
ways
Central Nervous System
Sympathetic Anterior
spinal nerve pituitary
ACTH
Epinephrine
Adrenal
Nor Adrenal
epinephrine cortex
medulla
Cortisol
i.e: cortisol
Controlled by HPA axis
During stress; 20x
Effects:
CHO production from protein & fat
(Gluconeogenesis)
Inflammation, Immune system
Other effects of Sympathetic and Cortisol
growth
reproduction, ovulation, sexual
activity, eating
Effects of Volume & Intensity of
Stressors Related to Hormones
Change in blood concetration
Hormones During intense, During moderate,
brief activity prolong activity
Epinephrine -
Norepinephrine -
Cortisol -
Growth Hormone -
Thyroxine -
Prolactin -
Recovery of stress
Super compensation
Protein synthesis
Repair of cell damage
Re-synthesis actins-myosin
c-leucine myosin
(super-compensation)
?
Thanks