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KELOMPOK 10

Rizki Setianingsih 4401414006
Rifki Dwi Anisa 4401414016

Perangkat yang Diperlukan dalam Sintesis Protein .

RNA (Ribonucleid Acid) .

Tipe Molekul RNA 1. pembawa informasi genetik dari DNA berbentuk triplet disebut kodon . RNA mesangger (RNAm) a. dicetak oleh DNA dalam inti b.

14a Anticodon .2. terdapat empat attachment site C A 5 daerah dengan basa G C G C C G yang berpasangan dan U U G A saling berikatan U C A A U U * C A C A G U A G A * * C U C b. basa yang tidak G C G U G U * C G A G G * * * U C A G G berikatan membentuk *GA G C * G C Hydrogen suatu lengkungan (loop) U A bonds * G A * A C * U A G A Figure 17. RNA transfer (RNAt) 3 A Amino acid C a.

5 Amino acid attachment site 3 Hydrogen bonds A A G 3 5 Anticodon Anticodon (c) Symbol used in this book (b) Three-dimensional structure .

komponen pembentuk ribosom b. RNA ribosom (RNAr) a.3. dihasilkan dari gen khusus (daerah pengatur nukleolus) pada kromatin .

berfungsi 1 snRNA Other proteins membentuk snRNPs Spliceosome spliceosomes. small nuclear RNA 5 RNA transcript (pre-mRNA) (RNAsn) Exon 1 Intron Exon 2 Protein a.4. yang berperan dalam 2 5 memotong dan membuang Spliceosome noncoding sequens components Cut-out (intron) dari gen inti 3 5 mRNA intron Exon 1 Exon 2 .

Ribosom • The ribosome has three binding sites for tRNA – The P site P site (Peptidyl-tRNA binding site) A site (Aminoacyl- – The A site E site tRNA binding site) – The E site (Exit site) Large subunit E P A mRNA binding site Small subunit (b) Schematic model showing binding sites. P. A ribosome has an mRNA binding site and three tRNA binding sites.16b ribosome will appear in later diagrams. and E sites. This schematic Figure 17. . known as the A.

Discharged tRNA leaves via the E site. The A site holds the tRNA carrying the next amino acid to be added to the polypeptide chain. Amino end Growing polypeptide Next amino acid to be added to polypeptide chain tRNA mRNA 3 Codons 5 (c) Schematic model with mRNA and tRNA. The P site holds the tRNA attached to the growing polypeptide. A tRNA fits into a binding site when its anticodon base-pairs with an mRNA codon. .

Perbandingan Ribosom Prokariotik Eukariotik .

Kode genetik Second mRNA base U C A G UUU UCU UAU UGU U Phe Tyr Cys Kodon UUC UCC UAC UGC C U Ser UUA UCA UAA Stop UGA Stop A nonsense Leu UAG Stop (terninator) UUG UCG UGG Trp G Third mRNA base (3 end) CUU CCU U First mRNA base (5 end) CAU CGU His CUC CCC CAC CGC C C Leu Pro Arg CUA CCA CAA CGA A Gln CUG CCG CAG CGG G AUU ACU AAU AGU U Asn Ser AUC lle ACC AAC AGC C A Thr AUA ACA AAA AGA A Met or Lys Arg Kodon Awal AUG start ACG AAG AGG G (Promotor) GUU GCU GAU GGU U GUC GCC GAC Asp GGC C G Val Ala Gly GUA GCA GAA GGA A Glu GUG GCG GAG GGG G .