KELOMPOK 10

Rizki Setianingsih 4401414006
Rifki Dwi Anisa 4401414016

Perangkat yang Diperlukan dalam Sintesis Protein .

RNA (Ribonucleid Acid) .

RNA mesangger (RNAm) a. pembawa informasi genetik dari DNA berbentuk triplet disebut kodon . dicetak oleh DNA dalam inti b. Tipe Molekul RNA 1.

RNA transfer (RNAt) 3 A Amino acid C a. basa yang tidak G C G U G U * C G A G G * * * U C A G G berikatan membentuk *GA G C * G C Hydrogen suatu lengkungan (loop) U A bonds * G A * A C * U A G A Figure 17.2.14a Anticodon . terdapat empat attachment site C A 5 daerah dengan basa G C G C C G yang berpasangan dan U U G A saling berikatan U C A A U U * C A C A G U A G A * * C U C b.

5 Amino acid attachment site 3 Hydrogen bonds A A G 3 5 Anticodon Anticodon (c) Symbol used in this book (b) Three-dimensional structure .

komponen pembentuk ribosom b. dihasilkan dari gen khusus (daerah pengatur nukleolus) pada kromatin .3. RNA ribosom (RNAr) a.

yang berperan dalam 2 5 memotong dan membuang Spliceosome noncoding sequens components Cut-out (intron) dari gen inti 3 5 mRNA intron Exon 1 Exon 2 . small nuclear RNA 5 RNA transcript (pre-mRNA) (RNAsn) Exon 1 Intron Exon 2 Protein a.4. berfungsi 1 snRNA Other proteins membentuk snRNPs Spliceosome spliceosomes.

Ribosom • The ribosome has three binding sites for tRNA – The P site P site (Peptidyl-tRNA binding site) A site (Aminoacyl- – The A site E site tRNA binding site) – The E site (Exit site) Large subunit E P A mRNA binding site Small subunit (b) Schematic model showing binding sites. A ribosome has an mRNA binding site and three tRNA binding sites.16b ribosome will appear in later diagrams. P. . This schematic Figure 17. known as the A. and E sites.

The A site holds the tRNA carrying the next amino acid to be added to the polypeptide chain. . Discharged tRNA leaves via the E site. Amino end Growing polypeptide Next amino acid to be added to polypeptide chain tRNA mRNA 3 Codons 5 (c) Schematic model with mRNA and tRNA. A tRNA fits into a binding site when its anticodon base-pairs with an mRNA codon. The P site holds the tRNA attached to the growing polypeptide.

Perbandingan Ribosom Prokariotik Eukariotik .

Kode genetik Second mRNA base U C A G UUU UCU UAU UGU U Phe Tyr Cys Kodon UUC UCC UAC UGC C U Ser UUA UCA UAA Stop UGA Stop A nonsense Leu UAG Stop (terninator) UUG UCG UGG Trp G Third mRNA base (3 end) CUU CCU U First mRNA base (5 end) CAU CGU His CUC CCC CAC CGC C C Leu Pro Arg CUA CCA CAA CGA A Gln CUG CCG CAG CGG G AUU ACU AAU AGU U Asn Ser AUC lle ACC AAC AGC C A Thr AUA ACA AAA AGA A Met or Lys Arg Kodon Awal AUG start ACG AAG AGG G (Promotor) GUU GCU GAU GGU U GUC GCC GAC Asp GGC C G Val Ala Gly GUA GCA GAA GGA A Glu GUG GCG GAG GGG G .