Scribd Logo
Importer

Bienvenue sur Scribd !

  • (Lecture 9) PRAKTIKUM CELL INJURY

    Transféré par

    anandarona
    62 vues33 pages
    This document discusses various types of cell adaptation, injury, and death: 1. Cell adaptation includes atrophy, hypertrophy, hyperplasia, and metaplasia. Cell injury can be reversible like swelling and fatty change, or irreversible including several types of necrosis and apoptosis. 2. Cell death pathways covered are coagulative necrosis, liquefactive necrosis, caseous necrosis, and enzymatic necrosis occurring in various disease states. Apoptosis is also discussed. 3. Types of intracellular and extracellular accumulation of lipids, proteins, and pigments like hemosiderin and mechanisms of pathologic calcification are summarized.

    Description originale:

    Titre original

    (lecture 9) PRAKTIKUM CELL INJURY.ppt

    Copyright

    © © All Rights Reserved

    Formats disponibles

    PPT, PDF, TXT ou lisez en ligne sur Scribd

    Avez-vous trouvé ce document utile ?

    Ce contenu est-il inapproprié ?

    Signaler ce document
    This document discusses various types of cell adaptation, injury, and death: 1. Cell adaptation includes atrophy, hypertrophy, hyperplasia, and metaplasia. Cell injury can be reversible like swelling and fatty change, or irreversible including several types of necrosis and apoptosis. 2. Cell death pathways covered are coagulative necrosis, liquefactive necrosis, caseous necrosis, and enzymatic necrosis occurring in various disease states. Apoptosis is also discussed. 3. Types of intracellular and extracellular accumulation of lipids, proteins, and pigments like hemosiderin and mechanisms of pathologic calcification are summarized.

    Droits d'auteur :

    © All Rights Reserved
    Téléchargez comme PPT, PDF, TXT ou lisez en ligne sur Scribd
    Signaler comme contenu inapproprié
    62 vues33 pages

    (Lecture 9) PRAKTIKUM CELL INJURY

    Transféré par

    anandarona
    This document discusses various types of cell adaptation, injury, and death: 1. Cell adaptation includes atrophy, hypertrophy, hyperplasia, and metaplasia. Cell injury can be reversible like swelling and fatty change, or irreversible including several types of necrosis and apoptosis. 2. Cell death pathways covered are coagulative necrosis, liquefactive necrosis, caseous necrosis, and enzymatic necrosis occurring in various disease states. Apoptosis is also discussed. 3. Types of intracellular and extracellular accumulation of lipids, proteins, and pigments like hemosiderin and mechanisms of pathologic calcification are summarized.

    Droits d'auteur :

    © All Rights Reserved
    Téléchargez comme PPT, PDF, TXT ou lisez en ligne sur Scribd
    Signaler comme contenu inapproprié
    sur 33

    CELL ADAPTATION,

    CELL INJURY,
    AND CELL DEATH

    Dr. dr. Ni Putu Sriwidyani, Sp.PA


    CELL ADAPTATION
    1. Atrophy
    2. Hypertrophy
    3. Hyperplasia
    4. Metaplasia
    Atrophy
    Endometrial atrophy in
    menopausal women
    Thinning of endometrial
    layer
    Small gland with low
    cuboids epithelium
    Hypertrophy
    Myocardium hypertrophy
    Enlarged cells around
    fibrosis (compare with the
    normal myocardium)
    Hyperplasia
    Prostate hyperplasia
    Increased gland/stromal
    component
    Increased cells
    Hyperplasia
    Endometrial hyperplasia
    Increased gland/stromal
    component
    Increased cells
    Metaplasia
    Cervical squamous metaplasia
    Gland epithelium replaced
    by squamous epithelium
    Metaplasia
    Barret metaplasia
    Squamous epithelium
    replaced by glandular
    epithelium
    CELL INJURY
    Reversible injury
    1. Cellular swelling
    2. Fatty change

    Irreversible injury
    1. Necrosis
    a. Coagulative necrosis
    b. Liquefactive necrosis
    c. Caseous necrosis
    d. Enzymatic necrosis
    2. Apoptosis
    Hepatocyte cellular swelling
    Enlarge of hepatocyte
    Granular cytoplasm
    Fatty change
    Clear (lipid containing)
    vacuoles in cytoplasm
    Eccentric located nuclei
    Coagulative necrosis
    Tumor cells
    Necrotic cells show
    eosinophilic cells
    Cell outline (+)
    Coagulative necrosis
    Hepar in septic shock
    Paracentral necrosis
    Necrotic cells show
    eosinophilic cells
    Cell outline (+)
    Liquefactive necrosis
    Acute appendicytis
    Cell outline (-)
    Replaced by inflammatory
    cells and cell debris
    Caseous Necrosis
    Lung tuberculosis
    Central necrosis
    (eosinophilic amorphous
    material), cell outline (-)
    Surrounded by epitheloid
    cells, lymphocyte, Langhans
    giant cell
    Tubercle (granuloma)
    formation
    Apoptosis
    Cancer cells
    Single cell
    Small, dense nuclei
    Intensely eosinophilic
    cytoplasm
    Intra & extra cellular accumulation

    1. Lipids
    a. Steatosis (Fatty change)
    b. Cholesterol (Atherosclerosis)
    2. Protein
    a. Hyaline change
    3. Pigment
    a. Melanin
    b. Carbon
    c. Hemosiderin
    Fatty change
    Clear (lipid containing)
    vacuoles in cytoplasm
    Eccentric located nuclei
    Atherosclerosis
    Intimal thickening
    (atheroma)
    Subintimal cholesterol
    deposition
    Dystrophic calcification
    Hyaline change
    Hyaline (amorphous eosinophilic)
    material in tubular lumina
    Melanin pigment
    Brown pigment
    Hemosiderin pigment
    Golden brown pigment in
    alveolar macrophages
    Pathologic calcification
    1. Dystrophic calcification
    2. Metastatic calcification
    Dystrophic calcification
    Fragmented basophilic
    material

    Vous aimerez peut-être aussi