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DEPART. OF MICROBIOLOGY,
MEDICAL FACULTY, HASANUDIN
UNIVERSITY
2007
Number of drugs available: limited
Difficult to obtain selective toxicity to virus:
replication of virus is the normal synthetic process
of the cell
Several virus-specific replication steps the site
of action of effective antiviral drugs.
Antiviral drugs are relatively ineffective: many cycle
of viral replication occur during the incubation time.
Some viruses become latent within the cell: no
current antiviral drugs can eradicate them.
Emergence of drug resistance viral mutans.
Inhibition of Viral Nucleic Acid Synthesis
Inhibition of Cleavage of Precursor
Polypetides
Inhibition of Viral Protein Synthesis
Inhibition of Release of Virus