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A.D.A
create a meal plan
works with your schedule
keeps your weight on track
improves your blood glucose, blood
pressure, and cholesterol numbers.
Carbohydrate Counting
Digital Sclerosis
Sometimes, people with diabetes develop tight, thick, waxy skin on the backs of their
hands. Sometimes skin on the toes and forehead also becomes thick. The finger joints
become stiff and can no longer move the way they should. Rarely, knees, ankles, or elbows
also get stiff.
This condition happens to about one third of people who have type 1 diabetes. The only
treatment is to bring blood sugar levels under control.
A is for A1C
Your A1C reflects your average blood glucose level for the two to
three month period before the test. Your healthcare provider uses it
to determine how well you are managing your blood sugar. A goal of
less than 7 percent is desirable, which corresponds to an average
blood glucose level of 150 mg/dL.
B is blood pressure
Men with diabetes should aim for a blood pressure level below
130/80 mm Hg. You should monitor blood pressure at each routine
diabetes visit.
C is for cholesterol (lipids)
A complete cholesterol test, referred to as a lipid panel or lipid
profile, includes the measurement of four types of fats (lipids) in your
blood, low-density lipoprotein (LDL), high-density lipoprotein (HDL)
cholesterol, total cholesterol and triglycerides. LDL is sometimes
called the "bad"cholesterol. Too much of it in your blood causes the
accumulation of fatty deposits (plaques) in your arteries
(atherosclerosis), which reduces blood flow. HDL is sometimes
called the "good"cholesterol because it helps carry away LDL
cholesterol, thus keeping arteries open and blood flowing more
freely. Total cholesterol is the sum of your blood's cholesterol
content. Triglycerides are another type of fat in the blood. When you
eat, your body converts any calories it doesn't need to use right
away into triglycerides, which are stored in fat cells and released
later for energy.
Note: Now you know your ABCs. Speak with your healthcare
provider about ways to keep your ABCs in control.
High Blood Pressure
(Hypertension)
As many as 2 out of 3 adults with diabetes have high blood pressure.
Because of the risks of high blood pressure to people with diabetes, the American
Diabetes Association and the National Institutes of Health recommend a lower blood
pressure target than the general public (less than 130/80 mmHg).
Blood pressure can be controlled with lifestyle changes, such as diet and exercise, and
medication.
An important part of taking care of yourself is keeping your blood pressure under control.
High blood pressure also called hypertension raises your risk for heart attack, stroke,
eye problems, and kidney disease. As many as 2 out of 3 adults with diabetes have high
blood pressure. Having your blood pressure checked regularly and taking action to reach
your blood pressure target can prevent or delay diabetes problems.
What is high blood pressure?
Blood pressure is the force of blood flow inside your blood vessels. When your health care
team checks your blood pressure, they record two numbers, such as 130/80 mmHg. You'll
hear them say this as "one-thirty over eighty." Both numbers are important:
The first number is the pressure as your heart beats and pushes blood through the blood
vessels. Health care providers call this the "systolic" pressure.
The second number is the pressure when the vessels relax between heartbeats. It's called
the "diastolic" pressure.
When your blood moves through your vessels with too much force, you have high blood
pressure. Your heart has to work harder when blood pressure is high, and your risk for
diabetes problems goes up. High blood pressure is a problem that won't go away without
treatment.
What is the recommended target for blood pressure?
Both diabetes and high blood pressure increases your risk of heart
attack, stroke, and eye and kidney disease. Because of this, people
with diabetes have a lower blood pressure target than the general
public. The American Diabetes Association (ADA) and the National
Institutes of Health recommend a target blood pressure of less than
130/80 mmHg for people with diabetes. When you keep your blood
pressure below 130/80 mmHg, you'll be lowering your risk for
diabetes problems.
How do I know if I have high blood pressure?
High blood pressure is a silent problem you won't know you have
it unless your health care provider checks your blood pressure. The
ADA recommends that you have your blood pressure checked at
every office visit, or at least 2 to 4 times a year.
How is it treated?
Both lifestyle changes and medication help control blood pressure.
Treatment differs from one person to the next. Work with your health
care provider to find a treatment that's right for you.
Lifestyle changes
Lifestyle changes can help control your blood pressure as well as your blood
glucose and blood lipids (cholesterol) levels. From the steps below, decide
which steps you would be willing to try. If you need more information about
how to make these changes, talk with your health care team.
Anger
Anger can start at diagnosis with the question, "Why me?" You may
dwell on how unfair diabetes is: "I'm so angry at this disease! I don't
want to treat it. I hate it!"
Denial
Denial is that voice inside repeating: "Not me." Most people go
through denial when they are first diagnosed with diabetes. "I don't
believe it. There must be some mistake," they say.
Depression
Feeling down once in a while is normal. But some people feel a
sadness that just won't go away. Life seems hopeless. Feeling this
way most of the day for two weeks or more is a sign of serious
depression.
Diabetes and Hearing Loss
Diabetes and hearing loss are two of Americas most widespread health concerns.
Nearly 26 million people in the U.S. have diabetes, and an estimated 34.5 million
have some type of hearing loss.
The numbers are similar is there a link?
Yes, says the National Institute of Health (NIH). In fact, the NIH has found that
hearing loss is twice as common in people with diabetes as it is in those who dont
have the disease. Also, of the 79 million adults thought to have pre-diabetes, the rate
of hearing loss is 30% higher than in those with normal blood sugar.
How does diabetes contribute to hearing loss?
Hearing depends on small blood vessels and nerves in the inner ear. Researchers
believe that, over time, high blood glucose levels can damage these vessels and
nerves, diminishing the ability to hear.
I dont think I have any problem with my hearing.
Are you sure? For most people, hearing loss happens over time. The symptoms can
be hard to notice. Quite often, family members and friends notice hearing loss before
the person experiencing it.
Your doctor may not always screen for hearing loss during a physical. Even if your
doctor does check for hearing loss, you may still pass the screening test in a quiet
exam room. Common signs of hearing loss include:
Frequently asking others to repeat themselves
Trouble following conversations that involve more than two people
Thinking that others are mumbling
Problems hearing in noisy places such as busy restaurants
Trouble hearing the voices of women and small children
Turning up the TV or radio volume too loud for others who are nearby
Im not even 65 how could my hearing be bad already?
Most people with hearing loss are younger than 65. Hearing problems can even
happen in children.
What should I do if I suspect a hearing loss?
Talk to your primary care doctor. You may then want to seek help from hearing
specialist like: an audiologist, a licensed hearing aid dispenser or a doctor who
specializes in hearing problems. From a full hearing exam, youll learn more
about your hearing loss. You will also be told what can be done to treat it.
What can be done to treat a hearing loss?
Sometimes the problem is just an earwax build-up and the patient is referred to
a doctor to remove the wax. Treatment will depend on the type of hearing loss.
The most common type of hearing loss is called sensorineural hearing loss,
This is the kind usually found with diabetes. It cannot usually be cured.
However, most cases of sensorineural hearing loss can be treated with hearing
aids.
How can I be sure that hearing aids will help?
Hearing aids have changed a lot in the past few years. Instead of making all
sounds louder, like the old kind, newer hearing aids are better at making what
you want to hear more clear. These hearing aids also have special features.
They may have automatic volume control and can reduce background noise.
But I dont want to be seen wearing hearing aids.
Hearing aids are getting smaller and smaller. It is unlikely anyone will notice
when you are wearing them. The truth is, people are more likely to notice your
hearing loss. People who dont treat their hearing problems can become
depressed and try to avoid their friends. On the other hand, studies show that
people who wear hearing aids often have a better quality of life.
Diabetes and Oral Health Problems
The more severe form of gum disease is called periodontitis.
When you reach this stage, your gums begin to pull away
from your teeth. Pockets form between your teeth and
gums. These fill with germs and pus, and deepen. When
this happens, you may need gum surgery to save your
teeth. If nothing is done, the infection goes on to destroy the
bone around your teeth. The teeth may start to move or get
loose. Your teeth may fall out or need to be pulled.
Is There an Association Between Gum Disease and
Diabetes?
For the nearly 24 million Americans that have diabetes,
many may be surprised to learn about an unexpected
complication associated with this condition. Research shows
that there is an increased prevalence of gum disease
among those with diabetes, adding serious gum disease to
the list of other complications associated with diabetes, such
as heart disease, stroke and kidney disease.
Is There a Two-Way Street?
Emerging research also suggests that the relationship between serious gum
disease and diabetes is two-way. Not only are people with diabetes more
susceptible to serious gum disease, but serious gum disease may have the
potential to affect blood glucose control and contribute to the progression of
diabetes. Research suggests that people with diabetes are at higher risk for
oral health problems, such as gingivitis (an early stage of gum disease) and
periodontitis (serious gum disease). People with diabetes are at an
increased risk for serious gum disease because they are generally more
susceptible to bacterial infection, and have a decreased ability to fight
bacteria that invade the gums.
The Surgeon General's Report on Oral Health states that good oral health is
integral to general health. So be sure to brush and floss properly and see
your dentist for regular checkups.
If I Have Diabetes, am I at Risk for Dental Problems?
If your blood glucose levels are poorly controlled, you are more likely to
develop serious gum disease and lose more teeth than non-diabetics. Like
all infections, serious gum disease may be a factor in causing blood sugar
to rise and may make diabetes harder to control.
Other oral problems associated to diabetes include: thrush, an infection
caused by fungus that grows in the mouth, and dry mouth which can cause
soreness, ulcers, infections and cavities.
How Can I Help Prevent Dental Problems Associated
with Diabetes?
First and foremost, control your blood glucose level.
Then, take good care of your teeth and gums, along with
regular checkups every six months. To control thrush, a
fungal infection, maintain good diabetic control, avoid
smoking and, if you wear them, remove and clean
dentures daily. Good blood glucose control can also help
prevent or relieve dry mouth caused by diabetes.
What Can I Expect at My Checkup? Should I Tell My
Dental Professional About My Diabetes?
People with diabetes have special needs and your
dentist and hygienist are equipped to meet those needs -
with your help. Keep your dentist and hygienist informed
of any changes in your condition and any medication you
might be taking. Postpone any non-emergency dental
procedures if your blood sugar is not in good control.
Gastroparesis
Gastroparesis is a type of neuropathy (nerve damage) in which food
is delayed from leaving the stomach.
This nerve damage can be caused by long periods of high blood
sugar.
Delayed digestion makes the management of diabetes more difficult.
It can be treated with insulin management, drugs, diet, or in severe
cases, a feeding tube.
Gastroparesis is a disorder affecting people with both type 1 and
type 2 diabetes in which the stomach takes too long to empty its
contents (delayed gastric emptying). The vagus nerve controls the
movement of food through the digestive tract. If the vagus nerve is
damaged or stops working, the muscles of the stomach and
intestines do not work normally, and the movement of food is slowed
or stopped.
Just as with other types of neuropathy, diabetes can damage the
vagus nerve if blood glucose levels remain high over a long period
of time. High blood glucose causes chemical changes in nerves and
damages the blood vessels that carry oxygen and nutrients to the
nerves.
What are the symptoms?
Signs and symptoms of gastroparesis include the following:
Heartburn
Nausea
Vomiting of undigested food
Early feeling of fullness when eating
Weight loss
Abdominal bloating
Erratic blood glucose (sugar) levels
Lack of appetite
Gastroesophageal reflux
Spasms of the stomach wall
These symptoms may be mild or severe, depending on the person.
What are the complications?
Gastroparesis can make diabetes worse by making it more difficult
to manage blood glucose. When food that has been delayed in the
stomach finally enters the small intestine and is absorbed, blood
glucose levels rise.
If food stays too long in the stomach, it can cause problems like
bacterial overgrowth because the food has fermented. Also, the food
can harden into solid masses called bezoars that may cause
nausea, vomiting, and obstruction in the stomach. Bezoars can be
dangerous if they block the passage of food into the small intestine.
How is it diagnosed?
The diagnosis of gastroparesis is confirmed through one or more of the
following tests:
Barium X-ray
After fasting for 12 hours, you will drink a thick liquid containing barium,
which covers the inside of the stomach, making it show up on the X-ray.
Normally, the stomach will be empty of all food after 12 hours of fasting. If
the X-ray shows food in the stomach, gastroparesis is likely. If the X-ray
shows an empty stomach, but the doctor still suspects that you have
delayed emptying, you may need to repeat the test another day. On any one
day, a person with gastroparesis may digest a meal normally, giving a
falsely normal test result. If you have diabetes, your doctor may have
special instructions about fasting.
Barium Beefsteak Meal
You will eat a meal that contains barium, which allows the doctor to watch
your stomach as it digests the meal. The amount of time it takes for the
barium meal to be digested and leave the stomach gives the doctor an idea
of how well the stomach is working. This test can help find emptying
problems that do not show up on the liquid barium X-ray. In fact, people who
have diabetes-related gastroparesis often digest fluid normally, so the
barium beefsteak meal can be more useful.
Radioisotope Gastric-Emptying Scan
You will eat food that contains a radioisotope, a slightly radioactive
substance that will show up on the scan. The dose of radiation from the
radioisotope is small and not dangerous. After eating, you will lie under a
machine that detects the radioisotope and shows an image of the food in
the stomach and how quickly it leaves the stomach. Gastroparesis is
diagnosed if more than half of the food remains in the stomach after two
hours.
Gastric Manometry
This test measures electrical and muscular activity in the stomach. The
doctor passes a thin tube down the throat into the stomach. The tube
contains a wire that takes measurements of the stomach's electrical and
muscular activity as it digests liquids and solid food. The measurements
show how the stomach is working and whether there is any delay in
digestion.
Blood tests
The doctor may also order laboratory tests to check blood counts and to
measure chemical and electrolyte levels.
To rule out causes of gastroparesis other than diabetes,
the doctor may do an upper endoscopy or an ultrasound.
Upper Endoscopy
After giving you a sedative, the doctor passes a long,
thin tube called an endoscope through the mouth and
gently guides it down the esophagus into the stomach.
Through the endoscope, the doctor can look at the lining
of the stomach to check for any abnormalities.
Ultrasound
To rule out gallbladder disease or pancreatitis as a
source of the problem, you may have an ultrasound test,
which uses harmless sound waves to outline and define
the shape of the gallbladder and pancreas.
How is it treated?
The most important treatment goal for diabetes-related gastroparesis is to manage
your blood glucose levels as well as possible. Treatments include insulin, oral
medications, changes in what and when you eat, and, in severe cases, feeding tubes
and intravenous feeding.
Insulin for blood glucose control
If you have gastroparesis, your food is being absorbed more slowly and at
unpredictable times. To better manage blood glucose, you may need to try the
following:
Take insulin more often
Take your insulin after you eat instead of before
Check your blood glucose levels frequently after you eat and administer insulin
whenever necessary
Your doctor will give you specific instructions based on your particular needs.
Medication
Several drugs are used to treat gastroparesis. Your doctor may try different drugs or
combinations of drugs to find the most effective treatment.
Meal and Food Changes
Changing your eating habits can help control gastroparesis. Your doctor or dietitian
will give you specific instructions, but you may be asked to eat six small meals a day
instead of three large ones. If less food enters the stomach each time you eat, it may
not become overly full. Or the doctor or dietitian may suggest that you try several
liquid meals a day until your blood glucose levels are stable and the gastroparesis
has improved. Liquid meals provide all the nutrients found in solid foods, but can
pass through the stomach more easily and quickly.
The doctor may also recommend that you avoid high-fat and high-fiber foods. Fat
naturally slows digestion something you don't need if you have gastroparesis
and fiber is difficult to digest. Some high-fiber foods like oranges and broccoli contain
material that cannot be digested. Avoid these foods because the indigestible part will
remain in the stomach too long and possibly form bezoars.
Feeding Tube
If other approaches do not work, you may need surgery to insert a feeding tube. The
tube, called a jejunostomy tube, is inserted through the skin on your abdomen into
the small intestine. The feeding tube allows you to put nutrients directly into the small
intestine, bypassing the stomach altogether. You will receive special liquid food to
use with the tube. A jejunostomy is particularly useful when gastroparesis prevents
the nutrients and medication necessary to regulate blood glucose levels from
reaching the bloodstream.
By avoiding the source of the problem (the stomach) and putting nutrients and
medication directly into the small intestine, you ensure that these products are
digested and delivered to your bloodstream quickly. A jejunostomy tube can be
temporary and is used only if necessary when gastroparesis is severe.
It is important to note that in most cases treatment does not cure gastroparesis it
is usually a chronic condition. Treatment helps you manage gastroparesis, so that
you can be as healthy and comfortable as possible.
Ketoacidosis (DKA)
Ketones are produced when your body starts burning fat for energy instead
of glucose.
Dangerously high levels of ketones can lead to diabetic coma or death.
Know the warning signs and check urine for ketones, especially when sick.
Ketoacidosis (key-toe-ass-i-DOE-sis) is a serious condition that can lead to
diabetic coma (passing out for a long time) or even death. When your cells
don't get the glucose they need for energy, your body begins to burn fat for
energy, which produces ketones. Ketones are acids that build up in the
blood and appear in the urine when your body doesn't have enough insulin.
They are a warning sign that your diabetes is out of control or that you are
getting sick. High levels of ketones can poison the body. When levels get
too high, you can develop diabetic ketoacidosis, or DKA.
Ketoacidosis may happen to anyone with diabetes, though it is rare in
people with type 2. Some older people with type 2 diabetes may experience
a different serious condition called hyperosmolar nonketotic coma (hi-per-
oz-MOE-lar non- key-TOT-ick KO-ma) in which the body tries to get rid of
excess sugar by passing it into the urine.
Treatment for ketoacidosis usually takes place in the hospital. But you can
help prevent ketoacidosis by learning the warning signs and checking your
urine and blood regularly.
What are the warning signs of ketoacidosis?
Ketoacidosis usually develops slowly. But when vomiting occurs,
this life-threatening condition can develop in a few hours. Early
symptoms include the following:
Thirst or a very dry mouth
Frequent urination
High blood glucose (sugar) levels
High levels of ketones in the urine
Then, other symptoms appear:
Constantly feeling tired
Dry or flushed skin
Nausea, vomiting, or abdominal pain
(Vomiting can be caused by many illnesses, not just ketoacidosis. If
vomiting continues for more than 2 hours, contact your health care
provider.)
A hard time breathing (short, deep breaths)
Fruity odor on breath
A hard time paying attention, or confusion
Ketoacidosis is dangerous and serious. If you have any of the above
symptoms, contact your health care provider IMMEDIATELY, or go to the
nearest emergency room of your local hospital.
How do I check for ketones?
You can detect ketones with a simple urine test using a test strip, similar to a
blood testing strip. Ask your health care provider when and how you should
test for ketones. Many experts advise to check your urine for ketones when
your blood glucose is more than 240 mg/dl.
When you are ill (when you have a cold or the flu, for example), check for
ketones every 4 to 6 hours. And check every 4 to 6 hours when your blood
glucose is more than 240 mg/dl.
Also, check for ketones when you have any symptoms of ketoacidosis.
What if I find higher-than-normal levels of ketones?
If your health care provider has not told you what levels of ketones are
dangerous, then call when you find moderate amounts after more than one
test. Often, your health care provider can tell you what to do over the phone.
Call your health care provider at once if you experience the following
conditions:
Your urine tests show high levels of ketones.
Your urine tests show high levels of ketones and your blood glucose level is
high.
Your urine tests show high levels of ketones and you have vomited more than
twice in four hours.
Do NOT exercise when your urine tests show ketones and your blood
glucose is high. High levels of ketones and high blood glucose levels can
mean your diabetes is out of control. Check with your health care provider
about how to handle this situation.
What causes ketoacidosis?
Here are three basic reasons for moderate or large
amounts of ketones:
Not enough insulin
Maybe you did not inject enough insulin. Or your body
could need more insulin than usual because of illness.
Not enough food
When you're sick, you often don't feel like eating,
sometimes resulting in high ketone levels. High levels
may also occur when you miss a meal.
Insulin reaction (low blood glucose)
If testing shows high ketone levels in the morning, you
may have had an insulin reaction while asleep.
Neuropathy (Nerve Damage)
Charcot's Joint
Charcot's Joint, also called neuropathic arthropathy, occurs when a joint
breaks down because of a problem with the nerves. This type of neuropathy
most often occurs in the foot.
In a typical case of Charcot's Joint, the foot has lost most sensation. The
person no longer can feel pain in the foot and loses the ability to sense the
position of the joint. Also, the muscles lose their ability to support the joint
properly. The foot then becomes unstable, and walking just makes it worse.
An injury, such as a twisted ankle, may make things even worse. Joints
grind on bone. The result is inflammation, which leads to further instability
and then dislocation. Finally, the bone structure of the foot collapses.
Eventually, the foot heals on its own, but because of the breakdown of the
bone, it heals into a deformed foot.
People at risk for Charcot's Joint are those who already have neuropathy.
They should be aware of symptoms such as swelling, redness, heat, strong
pulse, and insensitivity of the foot. Early treatment can stop bone
destruction and aid healing.
Cranial Neuropathy
Cranial neuropathy affects the 12 pairs of nerves
that are connected with the brain and control
sight, eye movement, hearing, and taste.
Most often, cranial neuropathy affects the nerves
that control the eye muscles. The neuropathy
begins with pain on one side of the face near the
affected eye. Later, the eye muscle becomes
paralyzed. Double vision results. Symptoms of
this type of neuropathy usually get better or go
away within 2 or 3 months.
Compression Mononeuropathy
Compression mononeuropathy occurs when a single nerve is
damaged. It is a fairly common type of neuropathy. There seem to
be two kinds of damage. In the first, nerves are squashed at places
where they must pass through a tight tunnel or over a lump of bone.
Nerves of people with diabetes are more prone to compression
injury. The second kind of damage arises when blood vessel
disease caused by diabetes restricts blood flow to a part of the
nerve.
Carpal tunnel syndrome is probably the most common compression
mononeuropathy. It occurs when the median nerve of the forearm is
compressed at the wrist. Symptoms of this type of neuropathy
include numbness, swelling, or prickling in the fingers with or without
pain when driving a car, knitting, or resting at night. Simply hanging
your arm by your side usually stops the pain within a few minutes. If
the symptoms are severe, an operation can give complete relief
from pain.
Femoral Neuropathy
Femoral neuropathy occurs most often in people with type 2
diabetes. A pain may develop in the front of one thigh. Muscle
weakness follows, and the affected muscles waste away. A different
kind of neuropathy that also affects the legs is called diabetic
amyotrophy. In this case, weakness occurs on both sides of the
body, but there is no pain. Doctors do not understand why it occurs,
but blood vessel disease may be the cause.
Focal Neuropathy
Focal Neuropathy affects a nerve or group of nerves causing
sudden weakness or pain. It can lead to double vision, a paralysis
on one side of the face called Bell's palsy, or a pain in the front of
the thigh or other parts of the body.
Thoracic/Lumbar Radiculopathy
Thoracic or lumbar radiculopath is another common
mononeuropathy. It is like femoral neuropathy, except that it occurs
in the torso. It affects a band of the chest or abdominal wall on one
or both sides. It seems to occur more often in people with type 2
diabetes. Again, people with this neuropathy get better with time.
Unilateral Foot Drop
Unilateral foot drop is when the foot can't be picked up. It occurs
from damage to the peroneal nerve of the leg by compression or
vessel disease. Foot drop can improve.
Steps to Prevent or Delay Nerve Damage
There's a lot you can do to prevent or delay nerve damage. And, if you already have diabetic
neuropathy (nerve damage), these steps can prevent or delay further damage and may lessen
your symptoms.
Keep your blood glucose levels in your target range.
Meal planning, physical activity and medications, if needed, all can help you reach your target
range. There are two ways to keep track of your blood glucose levels:
Use a blood glucose meter to help you make decisions about day-to-day care.
Get an A1C test (a lab test) at least twice a year to find out your average blood glucose for the
past 2 to 3 months.
Checking your blood glucose levels will tell you whether your diabetes care plan is working or
whether changes are needed.
Report symptoms of diabetic neuropathy.
If you have problems, get treatment right away. Early treatment can help prevent more
problems later on. For example, if you take care of a foot infection early, it can help prevent
amputation.
Take good care of your feet. Check your feet every day. If you no longer can feel pain in your
feet, you might not notice a foot injury. Instead, use your eyes to look for problems. Use a
mirror to see the bottoms of your feet. Use your hands to feel for hot or cold spots, bumps or
dry skin. Look for sores, cuts or breaks in the skin. Also check for corns, calluses, blisters, red
areas, swelling, ingrown toenails and toenail infections. If it's hard for you to see or reach your
feet, get help from a family member or foot doctor.
Protect your feet. If your feet are dry, use a lotion on your skin but not between your toes.
Wear shoes and socks that fit well and wear them all the time. Use warm water to wash your
feet, and dry them carefully afterward.
Get special shoes if needed. If you have foot problems, Medicare may pay for shoes. Ask your
health care team about it.
Be careful with exercising. Some physical activities are not safe for people with neuropathy.
Talk with a diabetes clinical exercise expert who can guide you.
Hyperosmolar Hyperglycemic
Nonketotic Syndrome (HHNS)
Hyperosmolar Hyperglycemic Nonketotic Syndrome, or HHNS, is a
serious condition most frequently seen in older persons. HHNS can
happen to people with either type 1 or type 2 diabetes, but it occurs
more often in people with type 2. HHNS is usually brought on by
something else, such as an illness or infection.
In HHNS, blood sugar levels rise, and your body tries to get rid of
the excess sugar by passing it into your urine. You make lots of
urine at first, and you have to go to the bathroom more often. Later
you may not have to go to the bathroom as often, and your urine
becomes very dark. Also, you may be very thirsty. Even if you are
not thirsty, you need to drink liquids. If you don't drink enough liquids
at this point, you can get dehydrated.
If HHNS continues, the severe dehydration will lead to seizures,
coma and eventually death. HHNS may take days or even weeks to
develop. Know the warning signs of HHNS.
What are the warning signs?
Blood sugar level over 600 mg/dl
Dry, parched mouth
Extreme thirst (although this may gradually disappear)
Warm, dry skin that does not sweat
High fever (over 101 degrees Fahrenheit, for example)
Sleepiness or confusion
Loss of vision
Hallucinations (seeing or hearing things that are not there)
Weakness on one side of the body
If you have any of these symptoms, call someone on your health
care team.
How can I avoid it?
The best way to avoid HHNS is to check your blood sugar regularly.
Many people check their blood sugar several times a day, such as
before or after meals. Talk with your health care team about when to
check and what the numbers mean. You should also talk with your
health care team about your target blood sugar range and when to
call if your blood sugars are too high, or too low and not in your
target range. When you are sick, you will check your blood sugar
more often, and drink a glass of liquid (alcohol-free and caffeine-
free) every hour. Work with your team to develop your own sick day
plan.
Related information
Another condition to watch signs for is ketoacidosis, which means
dangerously high levels of ketones, or acids, that build up in the
blood. Ketones appear in the urine when your body doesn't have
enough insulin, and can poison the body.
Kidney Disease (Nephropathy)
High blood sugar can overwork the kidneys, causing them to stop working
properly.
When diagnosed early, kidney disease can be slowed with treatment.
When diagnosed later, kidney failure usually results.
Once kidneys fail, replacement therapy via dialysis or transplant is necessary.
Kidneys are remarkable organs. Inside them are millions of tiny blood vessels that
act as filters. Their job is to remove waste products from the blood.
Sometimes this filtering system breaks down. Diabetes can damage the kidneys
and cause them to fail. Failing kidneys lose their ability to filter out waste products,
resulting in kidney disease.
How does diabetes cause kidney disease?
When our bodies digest the protein we eat, the process creates waste products.
In the kidneys, millions of tiny blood vessels (capillaries) with even tinier holes in
them act as filters. As blood flows through the blood vessels, small molecules
such as waste products squeeze through the holes. These waste products
become part of the urine. Useful substances, such as protein and red blood cells,
are too big to pass through the holes in the filter and stay in the blood.
Diabetes can damage this system. High levels of blood sugar make the kidneys
filter too much blood. All this extra work is hard on the filters. After many years,
they start to leak and useful protein is lost in the urine. Having small amounts of
protein in the urine is called microalbuminuria.
When kidney disease is diagnosed early, (during microalbuminuria), several
treatments may keep kidney disease from getting worse. Having larger amounts
of protein in the urine is called macroalbuminuria. When kidney disease is caught
later (during macroalbuminuria), end-stage renal disease, or ESRD, usually
follows.
In time, the stress of overwork causes the kidneys to lose their filtering ability.
Waste products then start to build up in the blood. Finally, the kidneys fail. This
failure, ESRD, is very serious. A person with ESRD needs to have a kidney
transplant or to have the blood filtered by machine (dialysis).
Who gets kidney disease?
Not everyone with diabetes develops kidney disease. Factors that can
influence kidney disease development include genetics, blood sugar control,
and blood pressure.
The better a person keeps diabetes and blood pressure under control, the
lower the chance of getting kidney disease.
What are the symptoms?
The kidneys work hard to make up for the failing capillaries so kidney disease
produces no symptoms until almost all function is gone. Also, the symptoms of
kidney disease are not specific. The first symptom of kidney disease is often
fluid buildup. Other symptoms of kidney disease include loss of sleep, poor
appetite, upset stomach, weakness, and difficulty concentrating.
It is vital to see a doctor regularly. The doctor can check blood pressure, urine
(for protein), blood (for waste products), and organs for other complications of
diabetes.
How can I prevent it?
Diabetic kidney disease can be prevented by keeping blood sugar in your
target range. Research has shown that tight blood sugar control reduces the
risk of microalbuminuria by one third. In people who already had
microalbuminuria, the risk of progressing to macroalbuminuria was cut in half.
Other studies have suggested that tight control can reverse microalbuminuria.
Treatments for kidney disease
Self-care
Important treatments for kidney disease are tight control of blood glucose
and blood pressure. Blood pressure has a dramatic effect on the rate at
which the disease progresses. Even a mild rise in blood pressure can
quickly make kidney disease worsen. Four ways to lower your blood
pressure are losing weight, eating less salt, avoiding alcohol and tobacco,
and getting regular exercise.
Drugs
When these methods fail, certain medicines may be able to lower blood
pressure. There are several kinds of blood pressure drugs, however, not all
are equally good for people with diabetes. Some raise blood sugar levels or
mask some of the symptoms of low blood sugar. Doctors usually prefer
people with diabetes to take blood pressure drugs called ACE inhibitors.
ACE inhibitors are recommended for most people with diabetes, high blood
pressure, and kidney disease. Recent studies suggest that ACE inhibitors,
which include captopril and enalapril, slow kidney disease in addition to
lowering blood pressure. In fact, these drugs are helpful even in people who
do not have high blood pressure.
Diet
Another treatment some doctors use with
macroalbuminuria is a low-protein diet. Protein seems to
increase how hard the kidneys must work. A low-protein
diet can decrease protein loss in the urine and increase
protein levels in the blood. Never start a low-protein diet
without talking to your health care team.
Kidney Failure
Once kidneys fail, dialysis is necessary. The person must
choose whether to continue with dialysis or to get a
kidney transplant. This choice should be made as a team
effort. The team should include the doctor and diabetes
educator, a nephrologist (kidney doctor), a kidney
transplant surgeon, a social worker, and a psychologist.
Peripheral Arterial Disease (PAD)
Smoking
High blood pressure
Abnormal blood cholesterol levels
Overweight
Not physically active
Over age 50
History of heart disease, or you've have had a heart attack or a stroke
Family history of heart disease, heart attacks, or strokes
You can't change your age or your family history, but taking care of your
diabetes and the conditions that come with it can lower your chances of
having PAD.
What are the warning signs of PAD?
Many people with diabetes and PAD do not have any symptoms. Some
people may experience mild leg pain or trouble walking and believe that it's
just a sign of getting older. Others may have the following symptoms:
Hemochromatosis
Hemochromatosis is a single-gene disease that
causes iron accumulation in the tissues of the
body.
Diabetes is a primary complication if
hemochromatosis, sometimes referred to as
"bronze diabetes," goes untreated.
It's fairly common, but often goes undiagnosed
and untreated.
It's treated effectively with frequent phlebotomy
(blood letting).
What is it?
Hereditary hemochromatosis is the most common single-gene
disease in Western populations, affecting 1 out of every 200-300
people. Yet it is almost unheard of by the general public, and many
health professionals are insufficiently aware of it. Because the
disorder can cause diabetes via damage to the pancreas, it is
something that deserves greater recognition in the American
Diabetes Association community.
Hereditary hemochromatosis is the most common of several "iron
overload" diseases, which are characterized by an excess
accumulation of iron in the body. In the case of hemochromatosis, a
single gene mutation causes extra iron to be absorbed from food in
the intestine, and the body lacks an efficient means of excreting the
excess iron it takes in. Over time, this iron accumulates in the
tissues of the body, most notably the pancreas, the liver, and the
heart. The extra iron builds up in the organs and damages them.
Without treatment, the disease can cause these organs to fail,
leading to diabetes, cirrhosis, and heart disease. In many patients,
the buildup of iron eventually becomes so excessive that it visibly
shows up in the skin, turning it a dark gray or bronze color. In fact,
hemochromatosis is sometimes referred to as "bronze diabetes"
because of the appearance of some patients when they are
diagnosed.
How common is it?
As many as 1 in 200 Americans are believed to carry both copies of the
gene for hemochromatosis, and it is estimated that about half of them will
eventually develop complications. That puts it roughly on a par with type 1
diabetes for prevalence. Like type 2 diabetes, it is severely underdiagnosed.
What are the symptoms?
Symptoms include the following and tend to occur in men between the ages
of 30 and 50 and in women over age 50 with joint pain being the most
common:
Joint pain
Fatigue
Lack of energy
Abdominal pain
Loss of sex drive
Symptoms typically seen with diabetes and heart disease
How is it diagnosed?
Blood tests (a transferrin saturation test or a serum ferritin test) can
determine whether the amount of iron stored in the body is too high. It is
also possible to test directly for the defective gene. Despite its prevalence
and the availability of simple tests for it, hemochromatosis is often
undiagnosed and untreated. The initial symptoms can be diverse and vague
and can mimic the symptoms of many other diseases. Also, doctors may
focus on the conditions caused by hemochromatosis arthritis, liver
disease, heart disease, or diabetes rather than on the underlying iron
overload.
What causes it?
Hemochromatosis is caused by a defect in a gene called HFE, which helps
regulate the amount of iron absorbed from food. A person who inherits the
defective gene from both parents (someone who is homozygous) may
develop hemochromatosis. Studies indicate that virtually everyone who is
homozygous for the HFE defect develops increased iron levels, with about
half of them developing complications as a result. People who inherit the
defective gene from only one parent (someone who is heterozygous) are
carriers for the disease but usually do not develop it, although they may
have slightly increased iron levels.
The Founder Effect: An Interesting Genetic Story
Hereditary hemochromatosis represents a striking example of the "founder
effect," which describes a genetic disease that arises from a mutation in just
one or a few individuals. In the case of hemochromatosis, it is believed that
a single individual in Europe, 60 to 70 generations ago, was the sole origin
of most of the hemochromatosis seen in the world today. A chance mutation
in the HFE gene in this individual was passed on, and because the
defective gene didn't cause any problems in people through child-bearing
age (and may have conferred some benefit in times of nutritional deficit),
there was no negative selection to stop it from being passed on. Because of
its origin, hemochromatosis today most often affects Caucasians of
Northern European descent, although other ethnic groups can be affected
by other iron overload diseases.
Men versus Women
Although both men and women can inherit the hemochromatosis gene, men are
much more likely to be diagnosed with the effects of hemochromatosis than women,
and men also tend to develop problems from the excess iron at a younger age. The
most likely explanation for the difference: menstruation and childbirth. Because
women regularly lose a significant amount of blood every month until menopause, as
well as during childbirth, they consequently lose a significant amount of iron
associated with that blood. For women who are homozygous for hemochromatosis,
the blood loss appears to be just enough to keep the hemochromatosis asymptomatic
until well after menopause.
How is it treated?
Once it is diagnosed, it is managed extremely effectively via frequent phlebotomy
(blood letting)
That difference between men and women in the progression of hemochromatosis is a
clue to the simple, straightforward treatment for hemochromatosis: phlebotomy, or
blood-letting. When first diagnosed, people with hemochromatosis are put on an
intensive schedule of phlebotomy to bring their iron levels down. They must give a
pint of blood once or twice a week, often for many months. Measures of blood iron
levels are monitored, and when they are finally in the normal range, the patient is put
on a maintenance schedule of giving a pint of blood at greater intervals, usually every
2 or 3 months. Unlike diabetes, hemochromatosis is virtually cured through its
treatment, with patients remaining completely asymptomatic as long as iron levels are
monitored and maintained in the normal range.
If treatment begins before any organs are damaged, associated conditions such
as liver disease, heart disease, arthritis, and diabetes can be prevented. The
outlook for people who already have these conditions at diagnosis depends on the
degree of organ damage. For example, treating hemochromatosis can stop the
progression of liver disease in its early stages, which means a normal life expectancy.
However, if cirrhosis has developed, the person's risk of developing liver cancer
increases, even if iron stores are reduced to normal levels. People with diabetes
resulting from pancreatic damage usually see an improvement if not a reversal of
their diabetes, depending on how much damage has occurred.
Where does the blood go?
The American Red Cross, which controls about 45% of the nation's blood
supply, does not currently accept donations from people with known
hemochromatosis. Everyone agrees that the blood is safe and of high
quality. There is no risk of passing on a genetic disease through blood
transfusions. But the Red Cross has a long-standing policy that potential
donors are not allowed to receive direct compensation for their donation
(beyond the usual orange juice and cookie). Because people with
hemochromatosis would otherwise have to pay for their therapeutic
phlebotomies, they would in effect be getting something of value for being
able to donate for free. Thus the Red Cross has ruled that such donations
violate their policy.
FDA regulations do permit hemochromotosis patients to donate blood, but
with some special restrictions on how the blood is marked and how the
blood banks operate. As a consequence, few blood blanks in the US
currently accept blood from people with hemochromatosis, and most of the
blood given as a result of therapeutic phlebotomy is discarded. (People with
hemochromatosis who wish to donate blood should check to see if any
blood banks in their area will accept their donations.) This is not true in
other countries, which have generally removed any restrictions on this
blood. The American Medical Association and many other groups have
advocated for removal of restrictions for the acceptance of blood donations
from people with hemochromatosis.
Agent Orange
Studies have shown that dioxin, a contaminant in the Agent Orange
herbicide, can cause a variety of illnesses in laboratory animals.
In 2000, the VA added type 2 diabetes to the list of "presumptive diseases
associated with herbicide exposure."
Vietnam veterans can get exams and medical treatment for Agent Orange-
related illnesses.
Vietnam veterans with type 2 diabetes are eligible for disability
compensation from the Department of Veterans Affairs (VA) based on their
presumed exposure to Agent Orange or other herbicides. In 2000, the VA
added type 2 diabetes to the list of "presumptive diseases associated with
herbicide exposure." That action followed a report from the National
Academy of Sciences that found "limited/suggestive" evidence of an
association between the chemicals used in herbicides during the Vietnam
War, such as Agent Orange, and type 2 diabetes.
The evidence of a link between exposure to Agent Orange (or dioxin, the
problematic contaminant in Agent Orange) and diabetes is modest. Most of
the association between Agent Orange and diabetes comes from studies of
people who lived near or worked at manufacturing plants that produced
large quantities of Agent Orange dioxin. In those cases, there appears to be
some relationship between Agent Orange exposure and increased insulin
resistance, the precursor to type 2 diabetes. In general the exposure that
Vietnam veterans had to Agent Orange was much less than in the
populations studied by scientists. Still, the VA has added diabetes to the list
of conditions for which Vietnam veterans are eligible for disability
compensation.
What is Agent Orange and what is dioxin?
Agent Orange was a herbicide used in Vietnam to kill unwanted plants and to remove
leaves from trees which otherwise provided cover for the enemy. In the 1970s some
veterans became concerned that exposure to Agent Orange might cause delayed health
effects. The concern about Agent Orange focuses not on the active ingredient, an
herbicide with little or no effect on animals, but on a trace contaminant in the herbicide,
dioxin. Studies have shown that dioxin and dioxin-like compounds (DLCs) can cause a
variety of illnesses in laboratory animals. More recent studies have suggested that the
chemical may be related to a number of types of cancer and other disorders.
In 1978, the Veterans Administration set up the Agent Orange Registry health
examination program for Vietnam veterans who were concerned about the possible
long-term medical effects of exposure to Agent Orange. Vietnam veterans who are
interested in participating in this Agent Orange program should contact the nearest VA
medical center for an examination.
Veterans who participate in the Agent Orange examination program are asked a series
of questions about their possible exposure to herbicides or Agent Orange in Vietnam. A
medical history is taken, a physical examination is performed, and there is a series of
basic laboratory tests. If medically required, consultations with other health specialists
are scheduled. However, no special Agent Orange tests are offered since there is no
test to show if any individual veteran's medical problem was caused by Agent Orange or
other herbicides used in Vietnam. There are tests that show body dioxin levels, but such
tests are not done by the VA because there is a serious question about their value to
veterans. The VA simply makes a presumption of Agent Orange exposure for Vietnam
veterans.
In its 1994 report on Agent Orange, the National Academy of Sciences (NAS) concluded
that individual dioxin levels in Vietnam veterans are usually not meaningful because of
background exposures to dioxin, poorly understood variations among individuals in
dioxin metabolism, relatively large measurement errors, and exposure to herbicides that
did not contain dioxin.
Benefits of the Agent Orange examination
The veteran is informed of the results of the Agent Orange examination during a
personal interview and gets a follow-up letter further describing the findings. Each
veteran is given the opportunity to ask for an explanation and advice. Where
medically necessary, a follow-up examination or additional laboratory tests are
scheduled. The examination and tests sometime reveal previously undetected
medical problems. These discoveries permit veterans to get prompt treatment for
their illnesses. Some veterans feel they are in good health, but are worried that
exposure to Agent Orange and other substances may have caused some hidden
illness. The knowledge that a complete medical examination does not show any
problems can be reassuring or helpful to Registry participants. All examination and
test results are kept in the veteran's permanent medical record. These data are
entered into the VA Agent Orange Registry.
Vietnam veterans can get medical treatment for Agent Orange-related illnesses.
Under Section 102, Public Law 104-262, the Veterans' Health Care Eligibility Reform
Act of 1996, the VA shall furnish hospital care and medical services, and may furnish
nursing home care to veterans exposed to herbicides in Vietnam. There are some
restrictions. The VA cannot provide such care for 1) a disability which VA determines
did not result from exposure to Agent Orange, or 2) a disease which the NAS has
determined that there is "limited/suggestive" evidence of no association between
occurrence of the disease and exposure to a herbicide agent.
The VA pays disability compensation to Vietnam veterans with injuries or illnesses
incurred in or aggravated by their military service. Veterans do not have to prove that
Agent Orange caused their medical problems to be eligible for compensation. Rather,
the VA must determine that the disability is "service-connected." A Veterans Services
Representative, at a VA medical center or regional office, can explain the
compensation program in greater detail and assist veterans who need help in
applying.
Frozen Shoulder
Frozen shoulder is a condition where progressively worse pain and stiffness
in the joint causes immobility of the shoulder.
Diabetes is a risk factor for frozen shoulder, but doctors are still researching
the relationship.
Physical therapy, though painful, is generally recommended.
A body in motion tends to stay in motion, and a body at rest tends to stay at
rest. Such is the case with your shoulder and a condition called adhesive
capsulitis. Adhesive capsulitis is more commonly known as frozen shoulder,
and with good reason: It can render your shoulder so stiff, it's almost
impossible to button your shirt that is, if you aren't in too much pain to get
dressed in the first place.
Frozen shoulder usually begins innocently enough. Your shoulder is
bothering you, so you don't use it. Sure, there's something to be said for
resting an overused joint after a weekend softball tournament. But if you've
injured your shoulder or are suffering from chronic shoulder pain and you
don't use your shoulder for a long time, your joint will stiffen up.
From there, it becomes a vicious cycle. If your joint begins to stiffen up, it's
more difficult and more painful to use your shoulder. So you use your
shoulder even less. Your shoulder gets more and more stiff, and eventually,
the lining of the joint gets stiff. Once that happens, you won't be able to
move your shoulder much, even if you want to. It simply won't budge past a
certain point because of pain and stiffness.
In general, frozen shoulder can come on after an injury to your
shoulder or a bout with another musculo-skeletal condition such as
tendonitis or bursitis. It can also develop after a stroke. Quite often
its cause can't be pinpointed. Nonetheless, any condition that
causes you to refrain from moving your arm and using your shoulder
joint can put you at risk for developing frozen shoulder.
Diabetes is also a risk factor for frozen shoulder, although precisely
why that's so is a subject the medical community is still researching.
One theory involves collagen, one of the building blocks of
ligaments and tendons. Collagen is a major part of the ligaments
that hold the bones together in a joint. Glucose (sugar) molecules
attach to collagen. In people with diabetes, the theory goes, this can
contribute to abnormal deposits of collagen in the cartilage and
tendons of the shoulder. The buildup then causes the affected
shoulder to stiffen up.
Overall, frozen shoulder affects about 20 percent of people with
diabetes, compared with 5 percent of people without diabetes.
Other risk factors are gender and age. Women are more likely to
develop frozen shoulder than men, and frozen shoulder occurs most
frequently in people between the ages of 40 and 60. It usually
affects only one shoulder at a time, and for reasons unknown, the
non-dominant shoulder is affected most often.
A Lengthy Condition
Frozen shoulder has several stages. First, there is the painful stage.
There is a general ache in the shoulder, and your muscles might
spasm. The pain may be worse at night. This stage can last
anywhere from a few weeks to eight months.
The next stage usually isn't as painful, but the shoulder does
become more stiff. This is when the ligaments shorten and do not
stretch, causing you to lose mobility in your shoulder. This
"stiffening" stage can last from two to six months.
Third is the recovery stage. Like the stiffening stage, this stage
generally is not as painful as the first stage. The ligaments start to
stretch and, gradually, your shoulder and arm regain some or most
of their natural movement. However, recovery may come in fits and
starts, with a bout of pain before each step along the way as the
lining of the joint stretches out. The recovery stage can last from one
to nine months.
So, if left to run its course, frozen shoulder can last from eight
months to 17 months or more. Some cases have lasted as long as
two years.
The Importance Of Early Treatment
Some doctors concentrate on pain relief during the first stage, but others, like Lori B.
Siegel, MD, chief of the division of rheumatology and associate professor of medicine
at Finch University of Health Sciences/Chicago Medical School in North Chicago, Ill.,
opt for a more aggressive approach. Siegel says keeping the shoulder moving, to
work the stiffness out of the ligaments and tendons so adhesions can't form, is the
way to go.
"If we catch it early, it might be possible to work through it with physical therapy, even
if there's some pain," she says. "But once you enter the middle stage, there's already
been some stiffness and that makes it tougher to work through."
She notes that in the middle stage, treatment can go beyond physical therapy and
exercise and include shots of saline or cortisone to help you regain shoulder mobility
and loosen up the stiff joint.
Most experts agree that physical therapy should be the first treatment attempted for
frozen shoulder. But such therapy, during which a therapist stretches and moves your
shoulder, along with daily home exercise, may not appear to make much sense,
especially if your shoulder hurts. After all, pain is an indication that something is
wrong, and it could be a sign of inflammation. Why move your shoulder if there is
pain and inflammation?
Because lack of use and motion is what leads to stiffness.
"Inflammation should be taken into consideration by your physical therapist, but
unless the shoulder is severely inflamed, you would want physical therapy" says
Michael Mueller, PT, PhD, associate professor at the Washington University School
of Medicine in St. Louis, MO. Anti-inflammatory drugs like ibuprofen can help bring
mild to moderate inflammation down to the point where you are able to start therapy.
After that, it's a matter of how much you hurt.
"The gauge is how much pain you are in," he says. "Your physical therapist should
work with you to see what you can tolerate." But if you cannot do physical therapy
because of pain, you should see your doctor for medication or shots.
How Early Is Early Enough?
How long should you wait before coming to the conclusion that this isn't "weekend
warrior" pain and it's time to go to the doctor?
That depends on what your symptoms are, says Rachel Peterson Kim, MD, staff
rheumatologist at the Scripps Clinic in La Jolla, CA. "If it's a mild nagging pain, you
can try rest, ice, and anti-inflammatory drugs such as ibuprofen for a week or two,"
she says. "But if you suddenly can't move it at all, or there's a lot of pain, see a
doctor."
If you've lost any mobility in your shoulder, it's time to see a doctor as well, says
Mueller. He suggests a simple test.
Lie on the floor or on your bed. Bring your arm up and over like you are doing a
backstroke. You should almost be able to touch the floor or bed with the back of your
hand. Of course, if you can actually touch it, that's great, but as long as you can
come within a few inches, that's fine. If not, you've lost some range of motion in your
shoulder and you should talk to your doctor about it.
When you go to your doctor, provide as much information as you can, and don't be
afraid to ask questions or repeat yourself. The shoulder is vulnerable to many
different conditions and injuries, and your doctor will need as much information as
possible to give you a correct diagnosis. It's not unheard of for a doctor to mistake
frozen shoulder for other conditions, particularly a torn rotator cuff.
"There are lots of different reasons for shoulder pain, and some doctors will think of
torn rotator cuffs because that is another important condition and part of so many
other problems," says Mueller. So don't be afraid to ask your doctor why he or she
has come to a diagnosis any diagnosis.
If your doctor confirms frozen shoulder, take his or her advice about exercise
seriously and act immediately, says Kim. "Patients should definitely be doing physical
therapy or exercises at home, in addition to their physical therapy, and they should
follow up with their doctors if there is no improvement," Kim says.
She adds that this is especially important for people with diabetes because they are
less likely than others to have a complete recovery, even with therapy. According to
Kim, permanent loss of as much as 50 percent of shoulder mobility can occur among
people with diabetes. (In the general population, any permanent decrease of range of
motion is usually negligible.) That's why it's so important to stack the odds in our
favor.
"We don't know why people with diabetes have a greater risk of incomplete recovery,"
she says. "No one has really looked at it yet. Is it their blood sugars? Are they less
active? I don't think there's a good answer for it yet."
Siegel adds that it's important not to ignore any signs that the condition is getting
worse. "It's easy to 'cheat' with the shoulder," she says. "A lot of people compensate
for it by bending in other ways or relying on other muscles, but that can lead to other
chronic pain syndromes. It's really a quality-of-life issue."
And if there's no improvement? If it's not getting worse, but it's not getting better
either, then it's time to consider more aggressive treatments, including surgery.
Your doctor may give you general anesthesia and then, while you are completely out
and unable to feel pain, manipulate your arm to loosen the joint. Surgery is the last
resort and should be approached with great caution because the condition usually
improves on its own over time.
The bottom line is, if you've had a traumatic injury to one of your shoulders, like a fall
or a blow, or you suddenly experience intense shoulder pain or a loss of mobility,
even for no apparent reason, get to a doctor. Then learn everything you can about all
of the treatment options available.
Insulin Storage and Syringe
Safety
Store your current bottle of insulin at room
temperature to avoid painful injections, but
keep extra supplies in the refrigerator.
Syringes can be reused safely, but it must
done carefully to avoid contamination.
Dispose of syringes in containers that
prevent the needles from causing harm
and check medical waste requirements for
your area
Insulin Storage
Although manufacturers recommend storing your insulin in the refrigerator,
injecting cold insulin can sometimes make the injection more painful. To
avoid this, many providers suggest storing the bottle of insulin you are using
at room temperature. Insulin kept at room temperature will last
approximately 1 month. Remember though, if you buy more than one bottle
at a time to save money, store the extra bottles in the refrigerator. Then,
take out the bottle ahead of time so it is ready for your next injection.
Here are some other tips for storing insulin:
Do not store your insulin near extreme heat or extreme cold.
Never store insulin in the freezer, direct sunlight, or in the glove
compartment of a car.
Check the expiration date before using, and don't use any insulin beyond its
expiration date.
Examine the bottle closely to make sure the insulin looks normal before you
draw the insulin into the syringe.
If you use regular, check for particles or discoloration of the insulin. If you
use NPH or lente, check for "frosting" or crystals in the insulin on the inside
of the bottle or for small particles or clumps in the insulin. If you find any of
these in your insulin, do not use it, and return the unopened bottle to the
pharmacy for an exchange and/or refund.
Syringe Reuse
Reusing syringes may help you cut costs, avoid buying
large supplies of syringes, and reduce waste. However,
talk with your doctor or nurse before you begin reusing.
They can help you decide whether it would be a safe
choice for you. If you are ill, have open wounds on your
hands, or have poor resistance to infection, you should
not risk insulin syringe reuse. Syringe makers will not
guarantee the sterility of syringes that are reused.
Here are some tips to keep in mind when reusing
syringes:
Keep the needle clean by keeping it capped when you're
not using it.
Never let the needle touch anything but clean skin and
the top of the insulin bottle.
Never let anyone use a syringe you've already used, and
don't use anyone else's syringe.
Cleaning it with alcohol removes the coating that helps
the needle slide into the skin easily.
Syringe Disposal
It's time to dispose of an insulin syringe when the needle is
dull or bent or has come in contact with anything other than
clean skin.
If you can do it safely, clip the needles off the syringes so no
one can use them. It's best to buy a device that clips, catches,
and contains the needle. Do not use scissors to clip off
needles the flying needle could hurt someone or become
lost.
If you don't destroy your needles, recap them. Place the
needle or entire syringe in an opaque (not clear) heavy-duty
plastic bottle with a screw cap or a plastic or metal box that
closes firmly. Do not use a container that will allow the needle
to break through, and do not recycle your syringe container.
Your area may have rules for getting rid of medical waste
such as used syringes. Ask your refuse company or city or
county waste authority what method meets their rules. The
CDC has more information about safe needle disposal in your
area.
When traveling, bring your used syringes home. Pack them in
a heavy-duty holder, such as a hard plastic pencil box, for
transport.
Other Injectable Medications
Pramlintide
Pramlintide (brand name Symlin) is a synthetic form of the hormone
amylin, which is produced along with insulin by the beta cells in the
pancreas. Amylin, insulin, and another hormone, glucagon, work in
an interrelated fashion to maintain normal blood glucose levels.
Pramlintide injections taken with meals have been shown to
modestly improve A1C levels without causing increased
hypoglycemia or weight gain and even promote modest weight loss.
The primary side effect is nausea, which tends to improve over time
and as an individual patient determines his or her optimal dose.
Because of differences in chemistry, pramlintide cannot be
combined in the same vial or syringe with insulin and must be
injected separately. Pramlintide has been approved for people with
type 1 diabetes who are not achieving their goal A1C levels and for
people with type 2 diabetes who are using insulin and are not
achieving their A1C goals.
Exenatide
Exenatide (brand name Byetta) is the first in a new class of drugs for the
treatment of type 2 diabetes called incretin mimetics. Exenatide is a
synthetic version of exendin-4, a naturally-occurring hormone that was first
isolated from the saliva of the lizard known as a Gila monster.
Exenatide works to lower blood glucose levels primarily by increasing
insulin secretion. Because it only has this effect in the presence of elevated
blood glucose levels, it does not tend to increase the risk of hypoglycemia
on its own, although hypoglycemia can occur if taken in conjunction with a
sulfonylurea. The primary side effect is nausea, which tends to improve over
time.
Like pramlintide, exenatide is injected with meals and, as with pramlintide,
patients using exenatide have generally experienced modest weight loss as
well as improved glycemic control. Exenatide has been approved for use by
people with type 2 diabetes who have not achieved their target A1C levels
using metformin, a sulfonylurea, or a combination of metformin and a
sulfonylurea.
Aspirin