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Skin Disorders
Made by alaa belal
Fungal Infections Hyperkeratosis
Canker sores
Disorders
Viral
Infections
Skin
Infestations Secondary bacterial
infections
Fungal Infections
Tinea
Types
Pedis
Corporis
Capitis
Unguium
Versicolor
1- Tinea pedis
Athletes foot
NOT just
athletes !!
But also:
Weak immune system
Older than 60
Diabetics
1- Tinea pedis
Athletes foot
Interdigital Moccasin Vesicular
Differences :
1)Occurs on arms, hands & feet
2)smaller
3)Middle part is not normal
4)Rare in patients under 20 years
Differential diagnosis
Tinea corporis Psoriasis
Immunological problem
Differences:
Not contagious
Red plaques covered with silvery-
white scales
Painful and sometimes crack &bleed
Similarities:
Itching Scaling
4- Tinea capitis
Ringworm of the scalp
Yeast
pitysporum orbiculare
Common in oily
surfaces
teenagers
Cosmetic concern
Not contagious
Differential diagnosis
Tinea versicolor Vitiligo
Water
Transmission of tinea
Prevention
Do not share
clothes, socks,
towels, nail
clippers
Indirect contact
Transmission of tinea
Prevention
Avoid contact
with infected
people or
animals
Direct contact
Transmission of tinea
Autoinfection
Treatment
Treatment of all fungal infections
Objective
Prevent
recurrence
Inhibit the
growth of fungus
Topical OTC
cream, solution, spray, powder
Scalp
Except Oral prescription
Nail
Oral prescription
Itraconazole
Oral prescription
Fluconazole
Oral prescription
Disadvantages
Nail Deficiency
Pregnancy
dystrophy diabetes
or breast in immune
or mellitus
destruction feeding system
Treatment of nail infection
(Tinea unguium)
Oral lamifen
Nail polish
Ticonazole
Surgically
Nail polish
Cleaning
Cutting
Apply
Oral prescription
Preventing reinfection
Shampoo
Commonly
comes back
after treatment
Treatment of tinea versicolor
Selenium sulfide
Sulfiselen Tinasel
Tinea capitis
Tinea unguium
Treatment
Azoles
Miconazole nitrate 2%
Thiocarbamates
Allylamines
Clioquinol
Undecylenic acid
Povidone iodine
Treatment
Azoles
Ketoconazole 2%
Thiocarbamates
Allylamines
Clioquinol
Undecylenic acid
Povidone iodine
Treatment
Azoles Available in all dosage
forms
Thiocarbamates Broad spectrum antifungal
Allylamines Apply twice daily
2 weeks for skin infection
Clioquinol 4 weeks for foot
6 weeks for scalp
Undecylenic acid few months for nail infection
Miconazole (Daktarin) safe
Povidone iodine in pregnancy
Treatment
Azoles Tolnaftate 1%
Thiocarbamates
Allylamines
Clioquinol
Undecylenic acid
Povidone iodine
Treatment
Azoles
Thiocarbamates Cream and
solution only
Allylamines Effective against most
Clioquinol dermatophytes not
only t.versicolor or
Undecylenic acid candidiasis
Povidone iodine
Treatment
Azoles
Terbinafine 1%
Thiocarbamates
Allylamines
Clioquinol
Undecylenic acid
Povidone iodine
Treatment
Azoles
Cream, solution, spray
Thiocarbamates tablets (but not otc)
Allylamines
Clioquinol
Undecylenic acid
Povidone iodine
Clioquinol + corticosteroid
Treatment
Azoles
Lotion, cream, ointment
Thiocarbamates
Side effects of clioquinol:
Allylamines May cause itching,
allergic contact
dermatitis
Clioquinol Interfere with thyroid
function
Undecylenic acid
Do not use <2 years
Povidone iodine
Treatment
Azoles
Thiocarbamates Undecylenic acid 10%
and 25%
Allylamines
Fungistatic
Clioquinol
Ointment at nighttime
Undecylenic acid
Powder at daytime
Povidone iodine
Treatment
Azoles Povidone iodine
Thiocarbamates 10%solution
(Betadaine)
Allylamines
Clioquinol
Undecylenic acid
Povidone iodine
Candidiasis
Candidiasis
Most common type of yeast infection
Symptoms
Thick, white lacy patches
on top of a red base
Where ??
Tongue
Palate
Or elsewhere
inside the mouth
Treatment
Topical oral antifungal
1- Miconazole
2- Nystatin
Treatment
1- Miconazole
area , as it adheres to the mucosal lining
Dose
spoonful spoonful
Infants Adults
Mundisal gel
Topical oral analgesic
BBC spray
Anti-inflammatory
Kenalog in orabase
Antiseptic and disinfectant agent
Self Healing
Patient counseling
Cause:
called
Microscopic mite Sarcoptes scabei
Scabies Symptoms
Itching
to appear in
Take from 4 to 8 weeks patients who have not been infected previously
to appear in
Take from 1 to 4 days Patients who have scabies before
Scabies
Transmission
Cause:
Small wingless parasitic insect
Pediculus humanus capitis
Head lice
Symptoms
Transmission
Pediculicides/scabicides Antipruritics
Piperonal
d-phenothrine
Treatment
Permethrin
Scabies Pediculosis
2.5-5% Permethrin Up to 1% Permethrin
d-phenothrine 0.4%
(Item shampoo)
Precautions
1- Avoid application to wounded skin or scalp to
avoid systemic absorption
Treatment
Pediculicides/scabicides Antipruritics
Piperonal
d-phenothrine
Treatment
Antipruritics
Helping provide relief of itching
HSV-1causes:
Herpetic labialis (cold sores)
Herpetic whitlow
Herpetic keratitis
HSV-2 causes:
Genital lesions
genital lesions and the virus is
never eliminated from the body
because The virus stays in the
ganglia in an inactive form.
Prevention
A vaccine called Zostavax to reduce the
risk of shingles in people ages 60 and over.
Acyclovir Zovirax
Penciclovir
Hypertrophy of the horny layer of the skin
Hyperkeratotic
(excessive development of keratin)
disorders
Callus
Skin lesions caused by
Excess friction
Over a broad
area of skin
Callus
Hand callus Feet callus
??
oozing
diabetes
mellitus
purulent
materials
Refer to a
dermatologist
peripheral rheumato-
circulatory id arthritis
disease
hemorrha- Hair
ging growth
Treatment
(keratolytic agent )
Mechanism of action :
It decreases ??
Salicylic acidadhesion
keratinocyte
It increases water binding ,which
leads to a hydration of keratin
Freezing method
Dimethyl ether (freezed)
Precautions
Avoid using salicylic acid, if you are
allergic to
NSAIDs
(aspirin, ibuprofen, .); or if you have any
other allergies
Secondary Bacterial Infection
SBI
Which bacteria causes SBI
Staphylococcus aureus
Streptococcus pyogenes
Staphylococcus aureus
Impetigo (school sores)
Staphylococcus aureus
Folliculitis
Staphylococcus aureus
Furunculosis (boils)
Which bacteria causes SBI
Staphylococcus aureus
Streptococcus pyogenes
Streptococcus pyogenes
Cellulitis
Streptococcus pyogenes
Erysipelas
Streptococcus pyogenes
Necrotising fasciitis
Treatment
Bacitracin Zinc
Neomycin
Polymyxin B Sulfate
Tetracycline
Fusidic acid
Tetracycline Fusidic acid
Terramycin Fucidin
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