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PSYCHOTIC
DRUGS
Antipsychotic medicines are primarily used to manage
psychosis. The word “psychosis” is used to describe
conditions that affect the mind, and in which there has
been some loss of contact with reality, often including
delusions (false, fixed beliefs) or hallucinations
(hearing or seeing things that are not really there). –
NIMH
DIVISION OF ANTI-
PSYCHOTIC DRUGS
1.Conventional Antipsychotics
- are the neuroleptic medications which were initially used to
treat schizophrenia for many years, dating as far back as
1952 when Thorazine made its debut in the United States.
This group of medications is also often referred to as “first
generation antipsychotics”, “typical antipsychotics”, and
“major tranquilizers”.
ziprasidone D2, 5-HT2A, 5-HT1A, 5-HT1D, 5-HT2C, 5-HT7, D3, a1, NRI, SRI
loxapine D2, 5-HT2A, 5-HT6, 5-HT7, D1, D4, a1, M1, H1, NRI
REFERENCES:
https://psychopharmacologyinstitute.com/antipsychotics-
videos/mechanism-of-action-of-antipsychotic-agents/
https://www.nimh.nih.gov/health/publications/attention-
deficit-hyperactivity-disorder-adhd-the-basics/index.shtml