ACID-BASE REGULATION

PHYSIOLOGI REGULATION
Kidney
Kidneys may require several hours to several days to
arrange basa.ginjal acid disorders using a mechanism
to regulate ion concentration can hydrogen.ginjal
mengabsorsibikarbonat for an excess of acid and
excrete during an acid deficiencies.
Lungs
Lungs Physiological buffers in the body are the lungs
and kidney. Lung can adapt quickly to their acid
imbalance basa. In fact, the lungs can make an effort to
restore the pH to normal values ​before biological
buffers can do.
 BIOLOGY REGULATION
Biological buffers occur if the hydrogen ion diarbsobsi
or released by cells tubuh.Ion hydrogen has a positive
charge and must be exchanged with positively charged
ions, the ions often used is kalium.Pada excess acid
conditions, hydrogen ions enter the cell and potassium ions
leave then enters the cell ekstrasel.Cairan extracellular fluid
then becomes less acidic because hydrogen ion is reduced
Biological buffer mode to 2 are: hemoglobin system
oksihemoglobin.Karbon dioxide diffuses into HR and form
carbonic acid karbonat.Asam split into hydrogen ions and
hydrogen bikarbonat.Ion bound to hemoglobin and
bicarbonate ions can be used to buffer a way to exchange it
chlorides which are extracellular
 CHEMICAL REGULATION
Buffer chemical most widely in the extracellular Caira is the
system carbonic acid-bicarbonate buffer. System responds in a few
seconds to change the ph, the system sehingan become the fastest
buffer system. This system is a system that is adaptive and has the
effect of which is relatively short. This system can be presented in
the form of the following equation.
The second chemical buffer system involving plasma proteins
(albumin, fibrinogen, and protombin) and gamma-globin, which
membenyuk about 6% to 7% of blood plasma. This protein can
release hydrogen ions or associated with acidosis or
alkalosis.namun to improve the capacity of plasma proteins to
maintain the acid-alkaline balance of the extracellular fluid is
limited, and the protein was not able to fix the acid-base
ketidakkeseimbangan take place in the long term.