Genitourinary

Pathology
Robert Pistey MD
Boston Medical Center
 QuickTime™ and a
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are needed to see this picture.
 Thyroid
“Thyroidization” of
kidney
Fibrosed
Gl.
Adult Polycystic
Kidney Disease
Chronic Renal
Dialysis
 Urothelial
(Transitional Cell)
Carcinoma
Tumor Normal
Renal Cell Carcinoma
Wilm’s Tumor
Metastatic Disease
Glomerular Diseases
Urinary Bladder
High grade dysplasia
/
Carcinoma-in-situ
Papillary Urothelial
Lesions of Bladder
Prostate
It’s Prostate
NOT
Prostrate!
Normal
Inflammation
Atrophy
Metaplasia
Hyperplasia
PIN
Adenocarcinoma
Benign mimics
ASAP
Special

Normal
Normal
Inflammation
Atrophy
Metaplasia
Hyperplasia
PIN
Adenocarcinoma
Benign mimics
ASAP
Special

Hyperplasia
Normal
Inflammation
Atrophy
Metaplasia
Hyperplasia
PIN
Adenocarcinoma
Benign mimics
ASAP
Special

Prostatic Intraepithelial
Neoplasia
(PIN)
Nelson, W. G. et al. N Engl J Med 2003;349:366-381
Normal
Inflammation
Atrophy
Metaplasia
Hyperplasia
PIN
Adenocarcinoma
Benign mimics
ASAP
Special

Adenocarcinoma
Nelson, W. G. et al. N Engl J Med 2003;349:366-381
 Gleason Score

Grade (1-5) + Grade (1-5) = Score (2-10)

Primary pattern Secondary pattern

Architecture only !
If pure (single) pattern use single grade x 2
 T1a = tumor incidentally found (<5% of
sample)
T1b = tumor incidentally found (>5% of
sample)
T1c = nonpalpable tumor found on core biopsy
pT2a pT2b pT2c

pT3a pT3b pT4