UPII Filing (E) - Version DCM MTG 070310

PART 1:
COMPLE
TE 1
Do you know?
DNA ，
is the secret of
youth ！
2
“DNA Skin Care”
- is the new skin care

trend for the 21st century
- is also an Anti-Aging
technology breakthrough
for the 21st century
3
Traditional anti-aging
replenishes nutrients to skin

cells,
repairs skin cells
However, this does not

solve skin aging at its
source
4
Care
penetrates into skin
layers, target skin aging
at the source (DNA)
DNA is being
revitalized ，
DNA activity is being
normalized.
A new generation of
high-powered skincare
5
DNA——
is the “Production Line” of
youth protein
6
3 main Youth
Proteins
Collagen Elastin Hyaluronic

Collagen is the Elastin fibers
Acid
connective tissue enable connecting
that gives our skin tissues to resume Hyaluronic Acids
structure, tone and their shape after enhance skin’s ability to
thickness stretching or retain moisture
contracting
7
When DNA production line becomes
less efficient ，
Youth Protein cannot be produced

effectively
that is the beginning of Skin Aging
8
Youth protein production line directly
impacts our Estrogen level
Youth protein
production line Skin aging
becomes less efficient
wrinkles
Estrogen Level DNA Collagen Skin texture is

Decreases compromised
damaged
Elastin pigmentation
Lost of skin
Hyaluronic radiance
acids
Dead skin cells
•Skin cells and its efficacy is directly impacted by our DNA

9
Beauty hormone (Estrogen)
Production
*Estrogen level of a womenofbegins
女性の一生と
Secretion to drop
女性ホルモ
Estrogen at age 25 and
ン分泌量
declines with by 40 years old, it
age
エストロゲン量（pg/ml）
drops even more drastically

25 years old
140
120
100
80
40 years old
30%
雌激素的生产
60
40 50 years old
20
0
70%
0 10 20 30 40 50 60 70 80 90 100
年龄年齢
Ref: creabeaux No. 39 (2004)

When
DNA Production Line
is healthy and complete ，
our skin will be healthy and

beautiful
11
Elysyle is presenting a technology breakthrough
anti-aging skin care range that fights aging at the
root cause - DNA
UPII Total Anti-Aging Skin Care
formulated with
14 natural ingredients
8 unique technology
providing you a complete range of anti-aging
skin care, you can enjoy anti-aging benefits
at every step of your skin care regimen!
12
A new generation of high-powered skin care that

fights aging at the root cause - DNA
13
USP(1)
more than 78 years of Skin
care research experiences
and 12 years of
Advanced Research on
Genesteine-S
14
USP(2)
14 Natural Ingredients
1) Simmondsia Chinensis (Jojoba) Seed Oil
2) Prunus Serrulata Flower Extract
3) Angelica Acutiloba Root Extract
4) Bidens Pilosa Extract
5) Coptis Japonica Root Extract
6) Rehmannia Glutinosa Root Extract
7) Glycine Soja (Soybean) Seed Extract
8) Lithospermum Officinale Extract
9) Coix Lacryma-Jobi Ma-Yuen Seed Extract
10) Oenothera Biennis (Evening Primrose) Seed Extract
11) Limnanthes Alba (Meadowfoam) Seed Oil
12) Clematis Chinensis Root Extract
13) Daucus Carota Sativa (Carrot) Root Extract
14) Saxifraga Sarmentosa Extract
15
USP(3)
8 Unique Technology
a) Anti-Aging Innovation: Genesteine-S
b) 16 types of amino acids (Bio-Amino Complex)
c) New HOC based Cleansing
d) Sense technology
e) Patented Technology with Oenothera biennis
extract
f) Using asparatic acid to maintain ideal skin pH level
g) Effectively tighten pores by Vitamin C derivatives
and Tannic acid
h) New Emulsifier Technology
16
Unique Technology (1)
1st to discover Anti-Aging Innovation: Genesteine-S
Delivering the latest

trend in DNA
Anti-Aging Skin Care
17
Genesteine-S
• First to discover that Genesteins-S is a natural and most powerful

Phytoestrogen
• From Prunus Serrulata, a Sakura species from the Rose family, and
Genesteine-S is extracted when the plant is at its most active level
• Only blooms once a year, and its life span is only 7 days
• It is a phytoestrogen that stimulates DNA transcription in our skin
cells to produce new youth proteins, skin natural lipids and
healthy skin cells.
18
Genesteine-S is at least 150% more

powerful phytoestrogen than other
700
plants used in Skin Care
Alfalfa
Wild Purple Yam
Phytoestrogen content (pg/ml)
600 Shepherd's-purse
Common Teasel
500
150% Fenugreek
400
Oats
300 Caiapo
Yam
200
Sakura Extract
100 Aniseed
0 Common Hop
Sage
Control
Phytoestrogen is effective in anti-aging by stimulating DNA

transcription
New Youth Anti-aging
Protein
x
wrinkles
x
Genesteine-S stimulates Skin texture
Phytoestrogen Collagen problem
DNA
transcripti
on Elastin x
Pigmentation
Activate estrogen receptors

Hyaluronic
x
Lost of Skin
Radiance
Genesteine-S stops
skin aging
Acid
x cells
Dead skin
DNA in skin cells

Dermis Epidermis 20
Genesteine-S is tested and proven
efficacy as Phytoestrogen &
Anti-oxidant:
• Activate the synthesis of collagen, elastin and

hyaluronic acid to prevent wrinkles formation
and improves skin elasticity
Phytoestrogen
• Activating epidermal cells and promotes
melanin discharging to reveal brighter skin
• Powerful anti-oxidant that neutralizes free

radicals for immense anti-aging effect
Anti-oxidant
Excellent Crème
16 Amino Acids (Bio-Amino Complex)
Bio-Amino Complex
4 Times (4X) +
Genesteine-S (16 Amino =
Acids)
Geneisteine-S + Bio-Amino Complex (16 amino acids) dramatically increases
skin fibroblast in dermal cells to:
Strengthen youth protein network
Revitalize and energize skin cells to repair skin damages
22
SINGAPORE MAGAZINE: ELLE
1 Amino Acids
SGD$1,800
(RM4,300)
RM1,300 RM2,100
RM550 RM2,280 RM4,100 23

TAIWAN MAGAZINE RM1,450
RM1,360
RM950
RM1,260
RM4,100
24
Unique Technology (2) Excellent Crème
The functions of 16 Kinds of Amino Acids

Complex
NMF ingredients Revitalizer
Taurine
Lysine HCI/ tyrosine/ histidine HCI
phenylalanine/ threonine
Serine/ asparagine acid Na Valine

glutamic acid/ arginine
glycine/ alanine/ proline
Leucine
Isoleucine
Collagen ingredients Energizer

Excellent Crème
Proven Clinical :
Dramatic Increase of fibroblasts in dermal cells
after application of UPII Excellent Crème
Before After
Bio-Amino Complex = 16 Amino
Acids Strengthen youth protein network
Recover skin cell energy
Natural moisturizing factor: Intense Hydration
Excellent crème is able to maintain natural moisturizing factor
more than 17% through 8 hours.
•1.4
Excellent creme
•1.3
Brand S
Hydration
•1.2
Brand N
•1.1
•After 1hour •After 4 hours •After 8 hours
Excellence Crème (RM395)
Japanese Popular Skin Care Brand S (RM1866)
Japanese Popular Skin Care Brand N (RM3731)
Double cleansing
Improved Micro HOC Base Technology:

retain skin moisture
New HOC base
Moist
ingredient Lather
keeping
ingredients
Washing ingredients
Moisture keeping power Double cleansing
After cleansing for 15 minutes, UPII’s moisture

content amount is 24% more than others.
110.0
100 is the amount of moisture just after wash
　 moistUP!
100.0
Moisture content ( ％ )
90.0
80.0
70.0
60.0
50.0
40.0
UPII UP Brand K
Brand S
Double cleansing
4. “Sense” Technology: remove dirt effectively
moisture dirt
• Automatically differentiates between facial dirt & moisture to remove

dirt while effectively retains skin moisture.
Deep care conc.
5 (a)Normalizes horny cells alignment creates a strong

barrier function for restoring skin moisture to maintain skin
moisture
Oenothera Biennis Extract
　 Immature CE
　 Mature CE
(Cornified cell envelope ）
Horny cells
　 Horny cells
horny
layer
epidermis
layer
Deep care conc.
5 (b) Oenothera Biennis Extract: Tested & proven results

As a mild exfoliator to enhance skin’s moisture keeping power and horny cells alignment
Before After
Balancing Lotion
6. New Asparatic Acid Technology:
maintain ideal skin pH level for self defense against skin aging
7.5
7
6.5 Only washing
pH H
6
肌のｐ
UP
5.5
Skin
Ideal pH balance UPII Only washing

5 洗顔のみ
MJ DL
UP
4.5 新MJ
UPII
4
洗顔前
Before 洗顔後
After ５分後
After 5 10分後
After 10 15分後
After 15
cleansing cleansing minutes minutes minutes
Balancing Lotion
7. Effectively tighten pores by Vitamin C

derivatives and Tannic Acid
Before After
Unique Technology 8
Essence crème lotion
8 (a) New Emulsifier technology ： Effectively delivers
the moisturizing and nutritious ingredients into skin dermal cells
to firms skin and enhanced skin elasticity
Normal Emulsifier New Emulsifier
Moisture
Effective
Lipophilic (oil base) ingredients
Hydrophilic (water base)

8 (b)Prolonged moisturizing effect
UPII has 29% more moisturizing effect after apply essence crème
lotion for 1 hour, 60% more after 3 hours and 100% more from 4th
hour onwards.
100.0
80.0
UPII
Moisture content
60.0
Brand B
40.0
20.0
0.0
0 1 2 3 4 5 6 7 8
To ensure maximum anti-aging action and results, use
UPII total anti-aging skin care range:
Daily:
•Step 1: UPII Double Cleansing Foam
(cleanse make-up & impurities while retaining skin
moisture)
•Step 2: UPII Deep Care Conc.
(Gentle skin exfoliation to improve skin metabolism)
•Step 3: UPII Balancing Lotion
(Brings skin to ideal pH level for skin protection)
•Step 4: UPII Essence Crème Lotion
(Moisturizes and nourishes skin, leaving skin soft and
skin does not feel oily)
Night: Repeat Step 1-3

UPII Excellent Crème
(With Bio-Amino complex that enhances skin fibroblast
during kin renewal process at night
Tested and Proven on Asian Skin
1. Visible wrinkle reduction – 91%
2. Skin is firmer – 82%
3. Smoother skin – 82%
4. Improved skin tone and radiance – 64%
* Consumer assessment - 30 subjects aged between 35- 55 years
- 8 weeks
USP (4)
Quality Assurance
39
USP (5)
5 “No”s
√ NO SLS* / SLES*
√ NO ARTIFICIAL FRAGRANCE
√ NO ANIMAL DERIVATIVES
√ NO ARTIFICIAL COLOURING
√ NO MINERAL OIL
40
Skin Care
begin from
“DNA” ，
Daily Skin Care

begin with “UPII” 41
With UPII Total Anti-Aging Skin
Care ，
We could look and feel better

than how we were yesterday!
Having our skin stay youthful

and beautiful
42
UPII Total
Anti-Aging
Skin Care
reveals youthful
and younger
looking skin 43
PART 2:
ANALYSI
S 44
Do you know?
DNA ，
is the secret of
youth ！
45
“DNA Skin Care”

46

cells,
repairs skin cells

source
47
Care
at the source (DNA)
DNA is being
revitalized ，
normalized.
A new generation of
48
DNA——
is the “Production Line” of
youth protein
49
3 main Youth
Proteins
Collagen Elastin Hyaluronic

Collagen is the Elastin fibers
Acid
connective tissue enable connecting
that gives our skin tissues to resume Hyaluronic Acids
structure, tone and their shape after enhance skin’s ability to
thickness stretching or retain moisture
contracting
50
When DNA production line becomes
less efficient ，
Youth Protein cannot be produced

effectively
that is the beginning of Skin Aging
51
Youth protein
wrinkles

damaged
Lost of skin
Hyaluronic radiance
acids
Dead skin cells

52
Production
女性の一生と
Secretion to drop
女性ホルモ
ン分泌量
age

25 years old
140
120
100
80
40 years old
30%
雌激素的生产
60
40 50 years old
20
0
70%
0 10 20 30 40 50 60 70 80 90 100
年龄年齢

When
DNA Production Line
is healthy and complete ，
our skin will be healthy and

beautiful
54
Elysyle is presenting a technology breakthrough
anti-aging skin care range that fights aging at the
root cause - DNA
formulated with
14 natural ingredients
8 unique technology
providing you a complete range of anti-aging
skin care, you can enjoy anti-aging benefits
at every step of your skin care regimen!
55
A new generation of high-powered skin care that

fights aging at the root cause - DNA
56
USP(1)
more than 78 years of Skin
care research experiences
and 12 years of
Advanced Research on
Genesteine-S
57
USP(2)
14 Natural Ingredients
1) Simmondsia Chinensis (Jojoba) Seed Oil
2) Prunus Serrulata Flower Extract
3) Angelica Acutiloba Root Extract
4) Bidens Pilosa Extract
5) Coptis Japonica Root Extract
6) Rehmannia Glutinosa Root Extract
7) Glycine Soja (Soybean) Seed Extract
8) Lithospermum Officinale Extract
9) Coix Lacryma-Jobi Ma-Yuen Seed Extract
10) Oenothera Biennis (Evening Primrose) Seed Extract
11) Limnanthes Alba (Meadowfoam) Seed Oil
12) Clematis Chinensis Root Extract
13) Daucus Carota Sativa (Carrot) Root Extract
14) Saxifraga Sarmentosa Extract
58
USP(3)
8 Unique Technology
a) Anti-Aging Innovation: Genesteine-S
b) 16 types of amino acids (Bio-Amino Complex)
c) New HOC based Cleansing
d) Sense technology
e) Patented Technology with Oenothera biennis
extract
f) Using asparatic acid to maintain ideal skin pH level
g) Effectively tighten pores by Vitamin C derivatives
and Tannic acid
h) New Emulsifier Technology
59
1st to discover Anti-Aging Innovation: Genesteine-S
Delivering the latest

trend in DNA
Anti-Aging Skin Care
60
Genesteine-S

Phytoestrogen
healthy skin cells.
61

700
Alfalfa
Wild Purple Yam
Common Teasel
500
150% Fenugreek
400
Oats
300 Caiapo
Yam
200
Sakura Extract
100 Aniseed
0 Common Hop
Sage
Control

transcription
Protein
x
wrinkles
x
DNA
transcripti
on Elastin x
Pigmentation

Hyaluronic
x
Lost of Skin
Radiance
Genesteine-S stops
skin aging
Acid
x cells
Dead skin
DNA in skin cells

Dermis Epidermis 63
Genesteine-S is tested and proven
efficacy as Phytoestrogen &
Anti-oxidant:
• Activate the synthesis of collagen, elastin and

hyaluronic acid to prevent wrinkles formation
and improves skin elasticity
Phytoestrogen
• Activating epidermal cells and promotes
melanin discharging to reveal brighter skin
• Powerful anti-oxidant that neutralizes free

radicals for immense anti-aging effect
Anti-oxidant
Excellent Crème
Bio-Amino Complex
4 Times (4X) +
Acids)
65
1 Amino Acids
SGD$1,800
(RM4,300)
RM1,300 RM2,100
RM550 RM2,280 RM4,100 66

RM1,360
RM950
RM1,260
RM4,100
67
The functions of 16 Kinds of Amino Acids

Complex
NMF ingredients Revitalizer
Taurine
Lysine HCI/ tyrosine/ histidine HCI
phenylalanine/ threonine
Serine/ asparagine acid Na Valine

glutamic acid/ arginine
glycine/ alanine/ proline
Leucine
Isoleucine
Collagen ingredients Energizer

Excellent Crème
Proven Clinical :
Before After
•1.4
Excellent creme
•1.3
Brand S
Hydration
•1.2
Brand N
•1.1
Double cleansing

New HOC base
Moist
ingredient Lather
keeping
ingredients
Washing ingredients

110.0
　 moistUP!
100.0
90.0
80.0
70.0
60.0
50.0
40.0
UPII UP Brand K
Brand S
Double cleansing
moisture dirt

Deep care conc.

moisture
　 Immature CE
　 Mature CE
Horny cells
　 Horny cells
horny
layer
epidermis
layer
Deep care conc.

Before After
Balancing Lotion
7.5
7
6.5 Only washing
pH H
6
肌のｐ
UP
5.5
Skin

5 洗顔のみ
MJ DL
UP
4.5 新MJ
UPII
4
洗顔前
Before 洗顔後
After ５分後
After 5 10分後
After 10 15分後
After 15
Balancing Lotion

Before After
Unique Technology 8
Moisture
Effective

hour onwards.
100.0
80.0
UPII
Moisture content
60.0
Brand B
40.0
20.0
0.0
0 1 2 3 4 5 6 7 8
Daily:
moisture)

- 8 weeks
USP (4)
Quality Assurance
82
USP (5)
5 “No”s
√ NO SLS* / SLES*
√ NO MINERAL OIL
83
Skin Care
begin from
“DNA” ，
Daily Skin Care

Care ，


and beautiful
85
UPII Total
Anti-Aging
Skin Care
reveals youthful
and younger
looking skin 86
PART 3:
EXPRES
S 87
Do you know?
DNA ，
is the secret of
youth ！
88
“DNA Skin Care”

89

cells,
repairs skin cells

source
90
Care
at the source (DNA)
DNA is being
revitalized ，
normalized.
A new generation of
91
Youth protein
wrinkles

damaged
Lost of skin
Hyaluronic radiance
acids
Dead skin cells

92
Production
女性の一生と
Secretion to drop
女性ホルモ
ン分泌量
age

25 years old
140
120
100
80
40 years old
30%
雌激素的生产
60
40 50 years old
20
0
70%
0 10 20 30 40 50 60 70 80 90 100
年龄年齢

Genesteine-S

Phytoestrogen
healthy skin cells.
94

700
Alfalfa
Wild Purple Yam
Common Teasel
500
150% Fenugreek
400
Oats
300 Caiapo
Yam
200
Sakura Extract
100 Aniseed
0 Common Hop
Sage
Control

transcription
Protein
x
wrinkles
x
DNA
transcripti
on Elastin x
Pigmentation

Hyaluronic
x
Lost of Skin
Radiance
Genesteine-S stops
skin aging
Acid
x cells
Dead skin
DNA in skin cells

Dermis Epidermis 96
Excellent Crème
Bio-Amino Complex
4 Times (4X) +
Acids)
97
1 Amino Acids
SGD$1,800
(RM4,300)
RM1,300 RM2,100
RM550 RM2,280 RM4,100 98

RM1,360
RM950
RM1,260
RM4,100
99
Excellent Crème
Proven Clinical :
Before After
•1.4
Excellent creme
•1.3
Brand S
Hydration
•1.2
Brand N
•1.1
Double cleansing

New HOC base
Moist
ingredient Lather
keeping
ingredients
Washing ingredients

110.0
　 moistUP!
100.0
90.0
80.0
70.0
60.0
50.0
40.0
UPII UP Brand K
Brand S
Double cleansing
moisture dirt

Deep care conc.

moisture
　 Immature CE
　 Mature CE
Horny cells
　 Horny cells
horny
layer
epidermis
layer
Deep care conc.

Before After
Balancing Lotion
7.5
7
6.5 Only washing
pH H
6
肌のｐ
UP
5.5
Skin

5 洗顔のみ
MJ DL
UP
4.5 新MJ
UPII
4
洗顔前
Before 洗顔後
After ５分後
After 5 10分後
After 10 15分後
After 15
Balancing Lotion

Before After
Unique Technology 8
Moisture
Effective

hour onwards.
100.0
80.0
UPII
Moisture content
60.0
Brand B
40.0
20.0
0.0
0 1 2 3 4 5 6 7 8
Daily:
moisture)

- 8 weeks
USP (4)
Quality Assurance
113
USP (5)
5 “No”s
√ NO SLS* / SLES*
√ NO MINERAL OIL
114
Skin Care
begin from
“DNA” ，
Daily Skin Care

Care ，


and beautiful
116

UPII Filing (E) - Version DCM MTG 070310

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UPII Filing (E) - Version DCM MTG 070310

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Formats disponibles

PART 1:

- is the new skin care

replenishes nutrients to skin

However, this does not

Collagen Elastin Hyaluronic

Youth Protein cannot be produced

that is the beginning of Skin Aging

Estrogen Level DNA Collagen Skin texture is

•Skin cells and its efficacy is directly impacted by our DNA

drops even more drastically

Ref: creabeaux No. 39 (2004)

our skin will be healthy and

A new generation of high-powered skin care that

1st to discover Anti-Aging Innovation: Genesteine-S

Delivering the latest

• First to discover that Genesteins-S is a natural and most powerful

Genesteine-S is at least 150% more

Phytoestrogen is effective in anti-aging by stimulating DNA

Activate estrogen receptors

DNA in skin cells

• Activate the synthesis of collagen, elastin and

• Powerful anti-oxidant that neutralizes free

16 Amino Acids (Bio-Amino Complex)

RM550 RM2,280 RM4,100 23

The functions of 16 Kinds of Amino Acids

NMF ingredients Revitalizer

Serine/ asparagine acid Na Valine

Collagen ingredients Energizer

Improved Micro HOC Base Technology:

New HOC base

Moisture keeping power Double cleansing

After cleansing for 15 minutes, UPII’s moisture

4. “Sense” Technology: remove dirt effectively

• Automatically differentiates between facial dirt & moisture to remove

5 (a)Normalizes horny cells alignment creates a strong

5 (b) Oenothera Biennis Extract: Tested & proven results

Ideal pH balance UPII Only washing

7. Effectively tighten pores by Vitamin C

Normal Emulsifier New Emulsifier

Hydrophilic (water base)

•Step 4: UPII Essence Crème Lotion

Daily Skin Care

We could look and feel better

Having our skin stay youthful

- is the new skin care

replenishes nutrients to skin

However, this does not

Collagen Elastin Hyaluronic

Youth Protein cannot be produced

that is the beginning of Skin Aging

Estrogen Level DNA Collagen Skin texture is

•Skin cells and its efficacy is directly impacted by our DNA

drops even more drastically

Ref: creabeaux No. 39 (2004)

our skin will be healthy and

A new generation of high-powered skin care that

1st to discover Anti-Aging Innovation: Genesteine-S

Delivering the latest

• First to discover that Genesteins-S is a natural and most powerful

Genesteine-S is at least 150% more

Phytoestrogen is effective in anti-aging by stimulating DNA

Activate estrogen receptors