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• 2. B cells go through a
process of producing a
clone of plasma cells
(antibody producing
cells) and memory cells.
• An individual may
recognize about 1015
different antigens
determined by their
genetic makeup.
V. B Cells and Humoral Immunity
• B. Antigen-Antibody Binding and its results
– Agglutination, Opsonization, Neutralization,
Complement activation, Inflammation, Antibody-
dependent cell-mediated cytotoxicity
Figure 17.14 - Overview
V. B Cells and Humoral Immunity
• C. Immunological Memory
– 1. Primary: gradual, several
days with no antibody, then
IgM, then IgG. Peak titers at
10-17 days.
– 2. Secondary Immune
Response: quick via memory
cells that persist for years,
primarily IgG. Some antibod y
already present followed by
peak in 2-7 days.
– 3. T cell memory is similar
and necessary for self vs
nonself recognition
The primary and secondary immune response to an antigen
Figure 17.15
VI.
T Cells and
Cell-
Mediated
Immunity