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When you breathe in, oxygen enters your lungs and is absorbed
into your blood which is pumped around your body by your heart.
The oxygenated blood allows the cells within your body to use
energy to help you exercise so the muscles can produce
movement.
When your cells produce energy and the muscles use the oxygen
up, a waste product called carbon dioxide is produced.
In the tissues of other organs a typical PO2 is 40 mmHg here haemoglobin has a
lower affinity for O2 and releases some but not all of its O2 to the tissues. When
haemoglobin leaves the tissues it is still 75% saturated.
Lungs at sea level: Lungs at high
PO2 of 100mmHg elevations: PO2
haemoglobin is 98% of 80mmHg,
SATURATED haemoglobin 95
% saturated
BLOOD TEMPERATURE
increased blood temperature
reduces haemoglobin affinity for O2
hence more O2 is delivered to
warmed-up tissue
BLOOD Ph
• lowering of blood pH (making blood
more acidic)
• caused by presence of H+ ions from lactic
acid or carbonic acid
• reduces affinity of Hb for O2
• and more O2 is delivered to acidic sites
which are working harder