NGUYỄN THỊ NGUYỆT NGUYỄN VĂN THÚC ĐỖ ĐĂNG TÂN TRẦN THỊ LÝ Bệnh nhân nữ 13 tuổi vào viện vì đau tức bụng vùng hạ vị 1 tuần nay. Tiền sử: -Chưa có tiền sử bệnh lí trước đây. -Chưa có kinh nguyệt. CTM SHM
TPT nước tiểu
=> Không thấy bất thường Siêu âm Dị dạng tử cung: tử cung có vách ngăn hoàn toàn với vách ngăn dọc âm đạo không thủng. after 6 weeks gestation, the absence of müllerian-inhibiting factor in the female fetus promotes bidirectional growth of the müllerian ducts 9 and 13 weeks gestation : paired müllerian ducts along the lateral aspect to form the primordium uterovaginal. 14 and 18 weeks gestation:the fused müllerian ducts undergo a process of reabsorption of the intervening uterovaginal septum 6-9w: uterine aplasia 9-13w: uterine duplications: a. Uterus didelphys (2 horn, 2 cervix). b. Bicornuate uterus (2 horn, 1cervix). 14-18w: septate uterus,arcuate uterus 5.5% in the general population 8% in infertile women 13.3% in women with a history of miscarriage 24.5% among women who have experienced miscarriage and infertility =>arcuate uterus was most common, affecting 3.9% of women. Majority are asymptomatic. Obstruction of the Müllerian duct: abdominal mass and dysmenorrhea. Recurrent miscarriages Infertility HSG allows evaluation of only the component of the uterine cavity cannot help to identify the type of MDA Ultrasound should be performed initially confirms any structural abnormalities of the genital tract sometimes cannot help to identify the type of MDA (especially on 2D imaging alone) MRI valuable noninvasive technique evaluation of the female pelvic anatomy accurate MDA classification Early developmental failure of the müllerian ducts results in agenesis or hypoplasia of the proximal two-thirds of the vagina, cervix, and uterus This anomaly is part of the Mayer- Rokitansky-Küster-Hauser syndrome 1/3 will have renal anomalies. absence of the cervix and uterus or rudimentary uterus vaginal atresia normal ovaries A unicornuate uterus results from normal development of one müllerian duct and near complete to complete arrested development of the contralateral duct Four subtypes: Uterus didelphys results from complete failure of müllerian duct fusion. Each duct develops fully with duplication of the uterine horns, cervix, and proximal vagina. Bicornuate uterus results from incomplete or partial fusion of the müllerian ducts Bicornuate uterus is characterized by the presence of a cleft (>1 cm in depth at MR imaging) in the external contour of the uterine fundus, similar to uterus didelphys. The septum is a result of complete or partial failure of reabsorption of the uterovaginal septum have a normal convex external fundal contour. • An arcuate uterus occurs with near reabsorption of the uterovaginal septum • have a normal convex external fundal contour DES-related anomaly of the uterus involves a hypoplastic or T-shaped uterus Features of a T-shaped uterus include: -a widened lower uterine segment -a small hypoplastic uterus -a narrowed fundal endometrial canal -irregular endometrial margins -intraluminal uterine filling defects Many patients are asymptomatic and require no treatment. However, where obstruction occurs, surgical intervention is usually required and may result in permanent infertility - counseling is required. • MDAs are a complex and broad spectrum of developmental anomalies that can manifest in a variety of both clinical and imaging scenarios. • US, MR imaging is currently the imaging modality of choice due to its reliability and accuracy • It is essential to accurately classify MDAs, as surgical planning often varies widely between MDA