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Hubungan Ilmu Biomedik Dasar dan

Ilmu Kedokteran Klinik

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Biomedical sciences are a set of applied sciences applying
portions of natural sciences or formal science, or both, to
develop knowledge, interventions, or technology that are of use
in health care or public health. Such disciplines as medical
microbiology,, clinical virology,,clinical epidemiology,, genetic
epidemiology,, and biomedical engineering are medical
sciences. In explaining physiological mechanisms operating in
pathological processes, however,pathophysiology can be
regarded as basic science..

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PENGORGANISASIAN SEL DALAM
TUBUH

SISTEM ORGAN

ORGAN ORGAN

JARINGAN JARINGAN JARINGAN

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SISTEM DALAM TUBUH
ORGANISME

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Penegakan Diagnosis

Penyakit yang disandang seseorang yang perlu ditolong


perlu ditegakkan disgnosisnya.
Bagaimana menegakkan suatu Penyakit?
 Perlu Pengetahuan: Patofisiologi & Patogenesis suatu Penyakit

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PATHOPHYSIOLOGY

1. The scientific study of the functional changes associated


with or resulting from disease or injury
2. The study of the biological and physical disturbances.
3. The pathophysiology does not deal directly with the
treatment of disease. Rather it explains the processes
within the body that results in the signs and symptoms of a
desease.
4. The study of structural and functional changes in the tissue
and organs that lead to diseases.

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PATHOPHYSIOLOGY OF RESPIRATORY SYSTEM

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LEARNING CONCEPTS

CORE CLINICAL PATHOPHYSIOLOGY SCIENTIFIC


SYSTEM CONCEPT
PROBLEM

haematology anemia Cell turn over


Chest pain Receptor
cardiovascular Growth Factor

Abdominal respiraory hypoxemia O2 transport


pain O2 transfer

Headache

Rash

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PATHOGENESIS
1. Pathogenesis is the development of disease, from the initial appearance of disease all
the way to its end stages. The study of pathogenesis is important for medical
professionals, as it helps them identify and treat diseases. It is also part of the work of
laboratory sciences who work on cures and treatments for diseases, as each stage of
development represents a potential possibility for interrupting the progression of the
disease.
2. The term “pathogenesis” comes from the Greek words for “disease” and “beginning.”
The origins of disease are the first step in pathogenesis, as are the progressive
changes which occur in the body as the disease takes hold and begins to act on the
body. For example, when someone is cut and the wound is colonized by
Staphylococcus bacteria, the bacteria cause inflammation ias they start to spread,
ultimately leading to infection. Each step from cut to full-blown infection is part of
the development.
3. There are a number of uses for the study of pathogenesis. In the case of individual
patients, it allows to a doctor to determine what caused a disease, and how the
disease can be treated. Being able to identify the stage which a disease has reached
can also be important for a doctor providing medical treatment, as in the case of an
oncologist who wants to determine the level of severity of a cancer.
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KESIMPULAN

Baik patofisiologi maupun patogenesis merupakan


pengetahuan yang diperlukan untuk menegakkan
diagnosis suatu penyakit, berkaitan erat dengan
struktur dan fungsi suatu organ yang tercakup dalam
suatu sistem organ.
Pengetahuan Biomedik dasar sangat diperlukan
sebagai pengetahuan untuk menegakkan diagnosis
suatu penyakit.

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