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Physiological Jaundice
Physiological Jaundice
Why ?
EXCLUSION CRITERIA
• Decreased uptake
• Decreased conjugation
Pathological Jaundice
Pathological Jaundice
Pathological Jaundice
Secondary to
Hemolysis due to
Hereditary spherocytosis
Scenario 4
Physiological Jaundice
Pathological Jaundice
Secondary to
Cephalhematoma
OTHER CAUSES OF UNCONJUGATED
HYPERBILIRUBINEMIA
• Interventions
– Intensive Phototherapy
– Exchange transfusion
Phototherapy
• Mechanism of action
• Technique
– Light source
• Lamps, spotlights, fiber optic blankets,
• Blue light
• Wave length: 420-500nm
• Irritability or lethargy
• Skin rashes
• Overheating
• Retinal injury
Exchange Transfusion
Bilirubin Encephalopathy
• Deposition of unconjugated bilirubin in the basal
ganglia and brainstem nuclei causing neurotoxic
effects