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C3
A 59 year-old female was admitted to R.D.
Kandou Hospital at C3 ward on Monday, April
10th, 2017 at 17.20 wita
Habit history :
Alkoholism (-), Smoking (-)
Family History
• None experienced the same illness
General anamnesis ( review of system )
General :-
Skin :-
Head and neck : -
Eye :-
Ear :-
Nose :-
Mouth and throat: -
Respiratory : -
Chest : Tumors on right breast
Heart :-
Abdomen : Vomitting
Genitalia :-
Kidney :-
Hematology :-
Endocrine :-
Musculosceletal : -
Physical Examination
• GC: Moderate ill Sens : CM
• C3:BP: 120/80mmHg, PR 96x/m, RR 20x/m, T 36,5ºC SaO2 98%
• ER :BP: 120/80mmHg , N 88x/m, RR 18x/m, T 36,3 C SaO2 98%
• BW 58 kg, BH 158 cm, BMI 23.3 kg/m2
• Head : conj. anemic (+), scl. icteric(-),
• Neck : JVP 5+0 cmH20, lymph nodes enlargement (+) right axilla
• Thorax (breast):
– Right : tumors +.7x5cm Ireguler, hard, no mobile, pain(-), peau d orange (-)
• Heart :
– Insp : IC not visible
– Palp : IC not palpable,
– Perc : left border: ICS V 1cm lateral midclavicullar line
right border: ICS IV sternal line
– Ausc : SI-II regular, murmur (-), gallop (-)
Physical examination
• Lung : Insp : Symmetric
Palp : stem fremitus R = L
Perc : sonor +/+
Ausc : vesicular, ronchi -/-, wheezing -/-
• Abd :
Insp : Flat
Palp : Tender, epigastric pain (+),
Liver and spleen not enlarged
Perc : Tympanic in all regions, shifting dullness (-)
Ausc : Bowel sound (+) normal
• Waist : Pain on CVA exam (-/-)
• Extr : warm, edema (-/-), washer women hands (-)
ECG : Sinus rhythm, 90x/min
ECG INTERPRETATION
ECG components Interpretation Value
Rhythm Sinus Sinus Rhythm
Speed / HR (times/mnt) 94x/min 1500/R-R’
Axis Normal Normal / RAD / LAD
Morphology P wave 0,10 sec Lead II : Duration ≤0.10”, Height ≤2.5”
PR Interval 0,20 sec 0,12” – 0,20”
QRS complex duration 0,08 sec 0,05” – 0,11”``
ST segmen Normal Normal / Elevated / Depressed
T wave Normal Normal / abnormal
QT Interval 0,40 sec cQT = QT interval / vR-R’ Interval
U wave Absent Appear / not appear
CONCLUSION : Sinus rhythm, HR 90x/m
No Problem List Plan Dx Plan Tx Non pharm tx Plan Monitoring
1 Na,K,Cl control o
IVFD Ns0,9%→ •Educate the •Observation for
•Vomitting 20gtt/m family about the vital signs.
•Pain at the •Ranitidin 2x1 iv condition of the
epigastrium •Ondancentron 3 patient and plans •Observation for
x 1 iv ahead. abdominal pain.
•Sucralfate 4 x cth
II po •Educate not to
GC: Moderately ill. take spicy food
Sens : CM
Abdomen: •Educate about a
epigastric pain on diet
palpation +.
→ Dyspepsia
syndrome
No Problem List Plan Dx Plan Tx Non pharm tx Plan Monitoring
2. Conj. Anemic (+) •Blood smear
o
PRC transfusion 1
bag/d till Hb>=10
•Educate the
family about the
•Observation for
vital signs.
Hb: 5.1 •CBC gr/dl condition of the
patient and plans
MCH 27 •Reticulocyte ahead.
MCHC 35
MCV 80
Anemia ec
malignancy
3. • Tumors right •Lab : DL, Consult •Educate the Observation for vital
breast since 1 • Diff count haematology family about the signs.
year Ca153 division condition of the
•FNAB patient and plans
PF : •USG abdoment ahead.
•CT Scan
Right : Tumor 7x5 cm, Thoraks pro
hard, immobile, staging
ireguler, pain (+),
bloody (+)
Ca Mammae
dextra
No Problem List Plan Dx Plan Tx Plan Plan Monitoring
Education
4 Na : 132 Na urine IVFD NaCl 0.9% 20 Educate the • Vital sign
gtt family about • Na serum
Na needed : 0.6 x the condition
58 x 10 = 348 meq of the patient
and plans
ahead.
Hyponatremia
Lab Result
9/4/2017
• Leucocyte 7300
• RBC 2.13
• Hb 5.1
• Ht 15.7
• Platelet 302,000
• MCH 27
• MCHC 35
• MCV 80
• RBS 129
• Ureum 21
• Creatinin 0.7
• Natrium 132
• Kalium 3.3
• Chloride 107
Problem List
No CM : 45.20.99 Age : 59 y.o
1. Main complain:
Vomitting
2. Anamnesis:
Epigastric pain
Tumors on right breast
3. Physical examination:
• GC: Moderate ill Sens : CM
C3:BP: 120/80mmHg, PR 88x/m, RR 20x/m
• Thorax (breast):
– Right : tumors +.7x5 cm. Ireguler, hard, no mobile, pain(-), peau d orange (+), bloody
(+)
Prognosis
• Ad Vitam : Dubia
• Ad Functionam : Dubia
• Ad Sanationam : Dubia
Conclusion
• Has been reported A 59 year-old woman
admitted to R.D. Kandou Hospital at C3 ward
on April 10th, 2017 at 17.20 with main
complain vomitting, from anamnesis, physical
examination an laboratory diagnosed with
Dyspepsia syndrome. Ca Mammae dextra.
Anemia ec malignancy. Hyponatremia.
Thank You
Definisi
• Dispepsia adalah kumpulan gejala nyeri
atau rasa tidak enak di abdomen atas
yang episodik atau persisten, kronik atau
rekuren yang disebabkan oleh berbagai
faktor
• Dikenal juga sebagai overlap syndromes
(sindroma tumpang tindih)
Etiologi
• Disebabkan oleh berbagai faktor
• Sekitar 50 – 60 % Pasien termasuk
kategori dispepsia fungsional
• Sekitar 40 % disebabkan oleh gangguan
struktur / organ
Tabel 1. Diagnosis Banding Penyebab Dispepsia
Kategori diagnostik Prevalensi
Dispepsia fungsional Sampai 60 %
Dispepsia karena penyakit struktural atau biokimia
Tukak peptik 15 – 25 %
Esofagitis refluks 5 – 15 %
Kanker lambung atau esofagus <2%
Penyakit saluran bilier Jarang
Gastroparesis Jarang
Pankreatitis Jarang
Malabsorbsi karbohidrate (laktose, sorbitol, fruktose, mannitol) Jarang
Obat – obatan Jarang
Penyakit infiltratif lambung (Penyakit Crohn, sarcoidosis) Jarang
Gangguan metabolik (hiperkalsemia, hiperkalemia) Jarang
Hepatoma Jarang
Penyakit usus iskemik Jarang
Penyakit sistemik (diabetes melitus, penyakit tiroid, and Jarang
paratiroid, penyakit jaringan ikat)
Parasit usus (Giardia, Strongyloides) Jarang
Kanker abdomen, terutama kanker pankreas Jarang
Patogenesis
• Ketidak seimbangan antara faktor agresif
dan faktor defensif
• Bila faktor agresif lebih kuat atau faktor
defensif lebih lemah maka akan terjadi
kerusakan mukosa gaster
DISPEPSIA
Investigasi
+ -
3. Sitoproteksi
a. Sucralfate d. Prostaglandin
b. Cetraxate e. Teprenone
c. Colloidal Bismuth subcitrate
4. Anti Free radical – Anti Inflamasi
a. Rebamipide
5. Eradikasi kuman H. pylori
DISPEPSIA
Tanda bahaya ;
Dispepsia (+)
Muntah hebat
Demam
Hematemesis
Serologi (tervadilasi lokal)
Anemia
Ikterus
Berat badan menurun
Hasil (+) Hasil (-)
Endoskopi
UBT / HpSA
Indeks retikulosit < 10% Indeks retikulosit 10-15% Indeks retikulosit > 15%
Anemia
MCV < 80fl & MCHC < 30g/dl
Indeks retikulosit < 10% Indeks retikulosit 10-15% Indeks retikulosit > 15%
Mielodisplasia
ACD
Algoritme Diagnosis Anemia Normositik Normokrom
Anemia
MCV 80-100fl & MCHC > 30g/dl
Indeks retikulosit < 10% Indeks retikulosit 10-15% Indeks retikulosit > 15%
Hipoplasia SSTL
Tes coombs, C3/C4 Negatif Positif Hb/
Cincin sideroblastik ? Anti DsDNA hemosiderin