Mycobacterium tuberculosis which is usually

transmitted through inhalation of saliva "droplets

from one individual to another, and forms
colonization in bronchioules or alveoli. Germs can
also enter the body through the digestive tract,
through ingestion of unpasteurized tainted milk,
or sometimes through skin lesions.
The main infectious agent, tuberculosis
microbacteria is an acid-resistant money-growing
aerobic stem that is slow and sensitive to heat
and ultraviolet light. Microbacterium bovis and
microbacterium avium once, in the event of 8
people, were associated with tuberculosis

infection .
• The entry of tuberculosis germs is the
respiratory tract, digestion, and open
wounds on the skin. However, most
infections occur through the air
through inhalation of droplets
containing tubercle bacilli bacteria
from infected people.
A. Primary tuberculosis

Primary tuberculosis is a 1B bacterial infection of patients

who do not have a specific reaction to bacteria TB. If TB
bacteria are inhaled from the air through the respiratory
tract and reach the alveoli or the terminal part of the
respiratory tract, the bacteria will be captured and
destroyed by the macrophages in the alveoli. if in this
process, bacteria are captured by weak macrophages, the
bacteria will multiply in the body of the weak macrophage
and destroy the macrophage
B. Secondary tuberculosis
• After resolution of the primary infection, a
small number of TB bacteria still live in a
dormant state in the scar tissue. As many as
90% of them do not experience recurrence.
Reactivation of TB disease occurs when the
immune system decreases, alcoholism,
malignancy, silicosis, diabetes mellitus, AIDS.
• In many individuals infected with
tuberculosis it is asymptomatic. in other
individuals, symptoms develop gradually
so that the symptoms are not recognized
until the disease has entered the
advanced stage.
• Severe illness can cause severe sepsis, respiratory failure, and
death. 1B which is resistant to drugs can occur. Possible other lines
that are drug resistant can occur. (Corwin Elizabeth. Pocket Book
Pathophysiology.Jakarta: Buku Kedokteran: egc TB disease; can
cause complications, namely attacking several vital organs of the
body, including:

1. Bone

2. Intestine

3. Brain

4. Kidney
• Ziehl Neelsen
• Sputum culture.
• Mantoux Skin test
• Chest X-ray
• Pulmonary tissue needle biopsy
• AGD
• pulmonary function examination
1. Shut your mouth when coughing and sneezing.

2. Spit should be at a certain place that has been given disinfectant (soapy
water).

3. BGC immunization is given to infants aged 3-14 months. 4. Avoid cold air.

4. Try to get enough sunlight and fresh air into the bed.

5. Drying mattresses, pillows and beds, especially in the morning.

6. All items used by sufferers must be separate as well as wash them and
may not be used by other people.

7. Food must be high in carbohydrates and high in protein.

The treatment for indicidu with active tuberculosis takes
a long time because the bacillus is resistant to most
antibiotics and mutates quickly when antibiotics are
still sensitive. At present, therapy for individuals with
active infection is a combination of four drugs and for
at least nine months or longer. if the patient does not
respond to these drugs, medication and other
treatment protocols will be sought.