Toxocara Canis

Infection
IN A 1-MONTH-OLD PUPPY
Pharmacology report in Antiparasitic Drugs

• TOGMOY,DAMERSON A. • PA N A N G O N , K AY Z E E A .
• PO,RODOLF VINCENT B. • MANZON, BRIAN
• PASCUA, ERIC ROBERTO • A P I G O, J A C Q U E S G L E N
 CONTENTS

VII. Discussion
I. Signalment
a) General Information
II. Case Information b) Pharmacology and Mechanism of Action
III. Clinical History c) Indications and Clinical Use
d) Precautionary Information
IV. Physical Examination e) Adverse Reactions and Side Effects
V. Laboratory Examination f) Contradictions and Precautions
VI. Treatment, Management and
Outcomes/Response to Medication IIX. References
 SIGNALMENT
 Name: Puppy
 Species: Canine
 Sex: Male
 Age: 1.5 months
 Weight: 1.6 kgs
 Breed: Mongrel
 Color: White and Brown markings
 Vaccination and deworming: No history tracing from the mother
 Diet: mixed
 CASE INFORMATION

 Date of admission: February 9,2019

 Clinic: AR Veterinary Clinic
 Attending Veterinarian: Dr. Aijeleth Shamar C. Jovellanos
 CLINICAL HISTORY

A 1.5 month old puppy was brought by the owner to the AR

veterinary clinic experiencing decrease in appetite and decrease
in activeness.The patient was lethargic.
PHYSICAL EXAM RESULTS
 PHYSICAL EXAM

 Mucous membrane: pale

 Circulatory CRT: 2sec
 Respiratory: normal breathing
 Nose: dry
 Muscular skeletal system: thin or emaciated
Laboratory Examination
 LABORATORY
EXAMINATION

 Direct smear Fecalysis

-Toxocara canis++

 Tentative diagnosis
-Parasitism
 TREATMENT, MANAGEMENT AND
OUTCOMES/RESPONSE TO MEDICATION
 TREATMENT

 Pyrantel(5 mg/kg once PO; repeat in 7-10 days)

-Anthelmintic drug(Dewormer)
 Papi MVP
- Multivitamins and minerals
 Papi Livwell syrup
- liver protectant, multivitamins, and good for the brain and the
heart.
 Dextrose powder
 FINAL REMARKS

The attending doctor advised the owner to

comeback after 2 weeks for followup check-
up.
DISCUSSION
Vincristine (vin-kriss’teen sul’fate)
 PYRANTEL
PAMOATE
(PYE-RAN’TEL)

Pharmacology
Trade and other names: Nemex, Strongid, Priex, Pyran, and Pyr-A-Pam
Functional classification: Antiparasitic
Class: tetrahydropyrimidines.
 PYRANTEL
PAMOATE
(PYE-RAN’TEL)

Pharmacology
Metabolism and Excretion:
The absorbed pyrantel and morantel are rapidly metabolized
(hydroxylation and conjugation) and excreted, mostly via feces, but also,
via urine.
 PYRANTEL
PAMOATE
(PYE-RAN’TEL)

Mode of Action
Acts to interfere with ganglionic neurotransmission via blocking with
acetylcholine receptors and other sites.
 PYRANTEL
PAMOATE
(PYE-RAN’TEL)

Clinical uses:
In dogs and cats, it is used for treatment of nematodes, including
Ancylostoma spp and Toxocara cati, T. canis, and Toxascaris leonina.
 PYRANTEL
PAMOATE
(PYE-RAN’TEL)

Precautionary Information
Contraindications and Precautions
No contraindications in animals. It may be used in all ages and in lactating and
pregnant animals
 REFERENCES

 Papich, M. G. (2016). Saunders handbook of veterinary drugs: Small and

large animal (4th ed.). St. Louis, MO: Elsevier. Pp. 384-392

 Hsu, W. H. (2008). Handbook of veterinary pharmacology. Seoul,

Republic of Korea: Shinilbooks books.Pp.392
END OF REPORT