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Case 2 FBS 1

Harrivcha W.S. Cika T.N.I. Anita K.


Bistamy M.N. Athayya N.S. Andini S. S.
Annisa N. Tasya E. Sarah L. A.
Annisa A. Hilmi A. Apridya N.
Annisa P. L. Arlo A.
BSCM
OCM
FCM
Learning Issues
Anatomy of Pancreas
Pancreas Secretion

Exocrine

1. Lipase
● Digest triglycerides
● Break TGA into fatty acids and monoglycerides
1. Amylase
● Hydrolysis polysaccharides into disaccharide and hyrdolysis disaccharide into
monosaccharide
1. Trypsin, chemotrypsin, and carboxypolipeptidase
● Trypsin and chemotrypsin break protein into small polipeptide
● Carboxypolupeptidase split amino acids

Endocrine

1. Langerhans cell produce glukagon and insulin for blood sugar balance
Physiology of Pancreas
1. Definition
2. Structure
3. Classification
4. Mechanism
Enzyme 5. Characteristics
6. Function
7. Inhibitor & Activator
Definition

Anita
Structure of Enzyme
Classification

Chhabra, N..; Classification of Enzymes, 2012, http://www.namrata.co/classification-of-enzymes/


Mechanism
Rodwell, V., Bender, D., Botham, K., Kennelly, P., Weil, P. ;Harper’s
Illustrated Biochemistry (2015), McGraw-Hill Education.

Mechanism
1 Catalysis by Proximity 2 Catalysis by Strain

3 Acid-Base Catalysis 4 Covalent Catalysis


Mechanism
Uji
(How to seperate the product )

1. Sequenced reaction
2. Double displacement reaction

Chang, Raymond. 2005. Physical Chemistry for the


Biosciences. Sausalito (CA): University Science
Books. p. 372-377.
Mechanism Cleland, Wallace. "Derivation of Rate Equations for Multisite Ping-
Pong Mechanisms with Ping-Pong Reactions at One or More Sites."
Journal of Biological Chemistry 248.24 (1973): 8353-355. Print.
Garrett, R., and Charles M. Grisham. "Gluconeogenesis, Glycogen
Metabolism, and the Pentose Phosphate Pathway." Biochemistry.
(How to seperate the product ) Belmont, CA: Brooks/Cole, Cengage Learning, 2010. 664-66. Print

1. Sequenced reaction
2. Double displacement reaction
Sarah
Hilmi
characteristic

Athayya
Cika

enzyme’s role
Inhibitor of Enzyme
Andin
Enzyme Activator

Definition: chemical compounds that increase a velocity of enzymatic reaction.


Tasya