PRESENTING

Alzheimer’s
Diseases
 SABUGA-A

LIVE

Alzheimer’s Diseases

Is a type of dementia that cause

problem with
memory,thinking and behavior

CONTENTS. 1 Contents
Dr.Alois Alzheimer
The condition usually affects
people above 60 yrs old.in some
cases ,early onset of the disease
occurs when the patients are in
their 30s or 40s. Women are
more likely to develop
alzheimer’s compered to men
HEALTHY
Alzheimers
Brain
NORMAL BRAIN AND HAVING ALZHEIMER
 Cause of having
Alzheimers
■PAST HEAD TRAUMA

People who've had a severe head trauma have a greater

risk of Alzheimer's disease.
• ■DOWN SYNDROME
• Many people with Down
syndrome develop Alzheimer's
disease. This is likely related to
having three copies of
chromosome 21 — and
subsequently three copies of the
gene for the protein that leads to
the creation of beta-amyloid.
Signs and symptoms of
Alzheimer's tend to appear 10 to
20 years earlier in people with
Down syndrome than they do for
the general population.
 Principle of stem cell therapy of Alzheimer

Stem cell therapy is one of the new-age therapeutic

approaches being explored for the treatment of Alzheimer's.
The plaques and tangles in the brain of an Alzheimer's
patient affect two essential proteins: ‘amyloid beta’ and ‘tau’.
Due to the damage to brain tissues, neutrophins are
produced in lesser quantities compared to a normal brain.
Stem Cell Research

• Scientists use different types of stem cells for this

purpose:
• Neural stem cells (NSCs)
• Mesenchymal stem cells (MSCs)
• Embryonic stem cells (ESCs)
• Induced pluripotent stem cells (iPSCs)
 Neural stem cells (NSCs)
Mesenchymal stem
cells (MSCs)
• Embryonic stem cells (ESCs)
•  Induced pluripotent
stem cells (iPSCs)
also, because the stem cell transplant
will only replace the damaged cells,
but will not cure the genetic cause of
alzheimer's, there could be chances of
relapses at least in some cases if not
in all.
stem cell therapy offers a new and
promising way to treat alzheimer's
disease, which is still an untreatable
disease today. around 5 million
americans are living with the disease,
and it’s dubbed as the 6th leading
cause of death in the united states.