Bacterial Infection of

Cardiovascular system
 Bacterial Infection of CVS

1. Bacteraemia
Presence of organisms not permanent. •
Organisms not multiplying. •
Patient asymptomatic. •
Important means of spread for other diseases. •
 Bacterial Infection of CVS
Causes of Bacteraemia
Group B streptococcus •
Escherichia coli (and other enteric Gram negative •
bacilli)
Listeria monocytogenes •
Streptococcus pneumoniae •
Haemophilus influenzae •
Staphylococcus aureus •
Neisseria meningitides •
Salmonella spp •
 Cardiovascular system (CVS)

2. Septicaemia
Septicaemia is a potentially life-threatening infection
in which large amounts of multiplying bacteria are
present in the blood. It is commonly referred to as
blood poisoning.
 Bacterial Infection of CVS

Septicaemia

Organisms actively multiplying. •

Patient acutely symptomatic. •
 Bacterial Infection of CVS
Causes
Septicaemia usually arises as a result of localised
infection in the body. The primary site of infection may
occur in the:
Respiratory system •
Skin •
The gastrointestinal system •
Genitourinary system. •
Bacteria usually spill over from the primary infection site
into the blood and are carried throughout the body
thereby spreading infection to various systems of the
body.
 Bacterial Infection of CVS

Symptoms
Fevers .1
Chills .2
Rash .3
 Bacterial Infection of CVS

Mortality
Very high even with prompt therapy. .1
Gram positive 10 – 20% .2
Gram negatuve 25 – 40% .3
Septic shock 40 – 90% .4
 Bacterial Infection of CVS

Endocarditis
 Bacterial Infection of CVS

3. Endocarditis
Viridans Streptococci
Streptococcus pneumoniae
Staphylococcus aureus
CoN Staphylococci
Stomatococcus species
Enterococcus species
 Bacterial Infection of CVS

3. Endocarditis (Cont.)
HACEK group
Bartonella species
Rickettsia burnetii
Brucella species
Erysipelothrix rhusiopathiae
Enterobacteriaceae
Ps. aeruginosa,
Corynebacterium sp.
Propionibacterium sp.
 Bacterial Infection of CVS

Myocarditis
 Bacterial Infection of CVS

4. Myocarditis
Cory.diphtheriae
Clostridium perfringens
group A Streptococcus
Borrelia burgdorferi
Neisseria meningitidis
Staphylococcus aureus
 Bacterial Infection of CVS

4. Myocarditis (Cont.)
Mycoplasma pneumoniae
Chlamydia pneumoniae
Chlamydia psittaci
Rickettsia rickettsii
Rickettsia tsutsugamushi
 Bacterial Infection of CVS

Pericarditis
 Bacterial Infection of CVS

5. Pericarditis
Streptococcus pneumoniae
Staphylococcus aureus
Neisseria gonorrhoeae
Neisseria meningitidis
Mycoplasma pneumoniae
Mycobacterium tuberculosis
 Bacterial Infection of CVS
Lab. Diagnosis
Microscopy
Gram stain
To detect:
Gram positive .1
2. Gram negative .2
 Bacterial Infection of CVS
Lab. Diagnosis
Blood culture:
To isolate the causative
agent (s).
 Bacterial Infection of CVS

Treatment
After performing
sensitivity test.