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Urinary/Renal systems
Frequency of urination (1st and last trimester)
Bladder capacity increases
Kidney filtration rate increases as much as 50%
Presence of protein indicates possible renal disease or PIH
Red Blood Cells
Stimulation of the bone marrow leads to 20-
20% increase in RBC.
Plasma volume increase is greater than the
RBC increase which leads to hemodilution,
typically referred as physiologic anemia of
pregnancy (pseudoanemia)
Hematocrit is decreased by 7%
WBC – increase up to 25,000/cu mm during
labor and delivery.
Musculoskeletal System
Increase in the normal-lumbosacral curve leads to backward tilt
of the torso
Center of gravity is changed, which often leads to leg and back
strain and predisposition to falling.
Pelvis relaxes due to the effects of the hormone relaxin; leads
to the characteristics “duck waddling” gait.
Gastrointestinal System
Pregnancy gingivitis – gums reddened, swollen and bleed easily
Increased saliva (ptyalism); decreased gastric acidity.
Decreased tone and motility of smooth muscles;
decreased emptying time of stomach; slowed
peristalsis due to increased progesterone leads to
complaints of bloating, heartburn, and constipation.
Nausea and vomiting in 1st trimester due to rising
levels of HCG.
Cravings or desires for strange food combinations
may occur.
Emptying time for gallbladder may be prolonged;
increased incidence of gallstones.
Integumentary
Increased skin pigmentation in various areas of the
body: Chloasma, striae gravidarum, linea nigra
Appearance of vascular nevi on the neck, arms and legs.
Greater sweat and sebaceous gland activity.
Endocrine System
Pituitary: FSH & LH greatly decreased; oxytocin secreted
during labor and after delivery; prolactin responsible for
initiation and continuation of lactation
Progesterone secreted by corpus luteum until formation
of placenta.
Principal source of estrogen is placenta.
Ovaries secrete relaxin during
pregnancy
Slight increase in thyroid gland
Increase in aldosterone, which retains
sodium.
Psychological Changes
1st Trimester
Mother needs accurate diagnosis of pregnancy.
Ambivalence
Mother is self-centered, baby “part” of her
2nd Trimester
Mother demonstrates growing realization of baby as separate
and needing person
Fantasizes about unborn child
3rd Trimester
“Nesting activity appears as due date approaches.
Desire to be finished with pregnancy.
Anxiety over “safe passage” for self and baby through labor and
delivery.
Preparation for Siblings.