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The Weeks Clinic for Corrective Medicine and Psychiatry 2011
www.weeksmd.com md@weeksmd.com
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Cancer Defined
DNA Damage
Toxic exposure Radiation Heavy metals Pesticides Synthetic hormones
CAT scan 1980 = 3 million people CAT scan 2007 = 70 million people Ionizing radiation meets living tissues => reactive oxygen and nitrogen species Remedy: Antioxidant & Anti-inflammation (water soluble and fat soluble)
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Anuploidy
Aneuploidy is probably the only mutation that can explain all aspects of carcinogenesis . On this basis we can now offer a coherent two-stage mechanism of carcinogenesis. In stage one, carcinogens cause aneuploidy which destabilizes the karyotype, and in stage two, aneuploidy evolves autocatalytically generating ever new and eventually tumorigenic karyotypes, ie. "genetic instability" . Thus cancer cells derive their unique and complex phenotypes from random chromosome number mutation, a process that is similar to regrouping assembly lines of a car factory and also to speciation. References: http://mcb.berkeley.edu/labs/duesberg/research.html http://barnesworld.blogs.com/barnes_world/2007/04/p ewter_duesberg.html
#1: Vitamin C is a protector against external radiation Pretreatment with Ascorbic Acid Prevents Lethal Gastrointestinal Syndrome in Mice Receiving a Massive Amount of Radiation.
From National Defense Medical College & Ground Self- Defense Force in Japan Yamamoto et al. J Radiat Res 2010;51:145-15.
A nuclear power plant accident occurred in 1999 in Japan. Patients who were exposed to high doses of radiation developed severe bone marrow failure, and thereafter underwent stem cell transplantation. However, they developed severe GI damage with diarrhea and bleeding, and eventually died from multiple organ failure.
Official Statement of JCIT about environmental radioactivity and health issued in March 29, 2011.
Atsuo Yanagisawa M.D. Masashi Uwabu, M.D. Burton E. Burkson, M.D. Bradford S. Weeks, M.D. Ronald Hunninghake, M.D. Steven Hickey, Ph.D. Thomas Levy, M.D. It is our strongest recommendation that those living in the
effected areas regularly take antioxidant supplements such as vitamin C to counteract the negative consequences of long-term low dose radiation exposure as well as to protect the health of coming generations. It is further recommended that those working in environments that require exposure to highconcentrations of radiation should immediately undergo ultra high dose vitamin C therapy along with a vigorous antioxidant supplementation program.
Orthomolecular approach #1
If environmental radioactivity became two-fold higher than usual, women with child bearing age should take the following basic anti-oxidative supplements to keep optimal anti-oxidative reserve.
Vitamin C 1-2 g 3-4 times a day Alpha-lipoic acid 100-200 mg Selenium 50-100g twice a day Vitamin E 100-200 mg twice a day with other essential vitamins and minerals. Liposomal Vitamin C 1 g twice a day twice a day
Orthomolecular approach #2
If environmental radioactivity became two-fold higher than usual, women with child bearing age should take the following basic anti-oxidative supplements to keep optimal anti-oxidative reserve. 2-4 g 3-4 times a day (increase to bowel Vitamin C
tolerance) OR Liposomal Vitamin C 3 g twice a day Alpha-lipoic acid 300 mg twice a day Selenium 200g twice a day Vitamin E 200 mg twice a day with other essential vitamins and minerals.
Orthomolecular approaches for people who works at radiation-contaminated area in the Fukishima Plant.
(1) I.V. Vitamin C 25g before and after work at radiation-contaminated area.
Sterile water 250mL with 50% vitamin C 50mL with 20% Mg chloride 5ml with 1% B12 1ml with B-complex 100 1ml with 10% B6 1mL with 25%Dexpanthenol 1mL - delivered 1 gm/min
(2) Daily supplements at work Liposomal Vitamin C 2 g three times a day Alpha-lipoic acid 300 mg twice a day
Corrective Supplements
NAC MOA = produces glutathione; Rx 1800mg Glutathione MOA = 1) radio protection, 2) produces cytokines which protect bone marrow from radiation; 200-600mg IM, IVP, IV, Neb S-Adenosylmethionine (SAMe) MOA= methyl group donor to enhance levels of glutathione; DNA protection from ionizing radiation; Rx 1,200mg a day
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Also worrisome
Modern Romance
He grasped me firmly, but gently, just above my elbow and guided me into a room, his room. Then he quietly shut the door and we were alone. He approached me soundlessly, from behind, and spoke in a low, reassuring voice close to my ear: "Just relax. Without warning, he reached down and I felt his strong, calloused hands start at my ankles, gently probing, and moving upward along my calves, slowly but steadily. My breath caught in my throat. I knew I should be afraid, but somehow I didn't care. His touch was so experienced, so sure. When his hands moved up onto my thighs, I gave a slight shudder and partly closed my eyes. My pulse was pounding.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Modern Romance
(cont.)
I felt his knowing fingers caress my abdomen, my ribcage. And then, as he cupped my firm, full breasts in his hands, I inhaled sharply. Probing, searching, knowing what he wanted, he brought his hands to my shoulders, slid them down my tingling spine and into my panties. Although I knew nothing about this man, I felt oddly trusting and expectant. This is a man, I thought. A man used to taking charge. A man not used to taking 'No' for an answer. A man who would tell me what he wanted. A man who would look into my soul and say: "Okay ma'am, you can board your flight now."
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Airport scanners
Invasion of the Body Scanners: Airport Security May Not Work, But It Does Cause Cancer
http://weeksmd.com/2010/11/travel-safe-and-avoid-the-scanners/
http://weeksmd.com/2010/11/airport-x-ray-scanners-i-recommend-avoiding-th
Day 2
Day 4
Day 6
Day 7
Day 9
Day 14
Day 17
The Tumor
Electrical Pollution
Where does it come from? What are the effects on electrical equipment? What are the effects on humans and animals? What has to be done to control it? What can we do?
BioElectric Smog
The Plague of st The 21 Century
The new environmental hazard Electrical Smog Measurable Preventable and Treatable!
My Medical Office
(before electriclearing)
8
TOXIC ! Computer On BioElectric Smog Count = (30X above upper limit if safety!)
1513
Resources: www.safalab.com (search filter) www.weeksmd.com (search electric) www.emrpolicy.org www.electricalpollution.com Further Reading: Becker, Robert The Body Electric Becker Robert Cross Currents Brodeur, Paul Currents of Death and articles in The New Yorker Magazine
A Brief History
1972 oil embargo forced U.S. to become more energy efficient Equipment was designed to operate using short pulses of current instead of continuous current Variable speed frequency drives, HID lighting, dimmer switches, computers, TVs, and most other modern electronic devices are energy efficient
Linear Loads
Prior to 1972, most electrical loads were linear; that is, they operated on normal utility supplied 60-Hertz sine waves Linear loads include devices such as motors and incandescent light bulbs With linear loads, higher voltage potential means higher current draw, and vice versa
Non-linear Loads
Non-linear loads use short pulses of current Therefore, load current is NOT proportional to the voltage applied When load current & voltage are NOT proportional entities, harmonics are generated and flow on the power
Electrical Pollution
Power Quality Definition: Anything that deviates from a normal sinusoid Contributors to Electrical Pollution:
1. 2. 3. 4. Harmonics Transients Sags Swells
2Enertech
. . . the absolute (as well as modest) level of contact current surfaces. This ``open circuit voltage'' (V(18 cause ``contact current'' to flow in a person electric fields in tissue modeled ) will uA) produces average who touches the appliance and completes an electrical circuit to ground. This paper presents data along its path that exceed 1 mV/m. At and above this level, suggesting that contact current due to V is an exposure that may explain the reported associations of residential magnetic fields with childhood leukemia. Our analysis is based on a computer model the NIEHS Working Group [1998] accepts that biological of a 40 house (single-unit, detached dwelling) neighborhood with electrical service that is effects relevant motivated by recent research suggesting representative of US grounding practices. The analysis was to cancer have been reported in that the physical location of power lines in the backyard, in contrast to the street, may be relevant to numerous well-programmed studies. a relationship of power lines with childhood leukemia. In the model, the highest magnetic field
Residential electrical wiring safety practices in the US result in the possibility of a small voltage (up to a few tenths of a volt) on appliance surfaces with respect to water pipes or other grounded
OC OC
levels and VOCs were both associated with backyard lines, and the highest VOCs were also associated with long ground paths in the residence. Across the entire neighborhood, magnetic field exposure was highly correlated with VOC (r0.93). Dosimetric modeling indicates that, compared to a very high residential level of a uniform horizontal magnetic field (10 mT) or a vertical electric field (100 V/m), a modest level of contact current (18 mA) leads to considerably greater induced
Ground Current
1960s: Linear Loads 100 amps current on phase conductors 100% returned via ground
100
on phase conductors
70% returned via ground
700
Cherry Report
This review cites a great deal of internationally published peerreviewed scientific evidence from laboratories and universities around the world, sourced from reports from reputable institutions and in internationally published papers from peer-reviewed journals. This shows compelling evidence of athermal biological changes in cells and in animals, which relate to brain function change, sleep disruption, chronic fatigue, reproductive problems and adverse health problems such as immune system impairment and cancers of many organs. Epidemiological studies have identified statistically significant increases of the incidence of most of these symptoms and diseases associated with above average exposure to radio-frequency and microwave (RF/MW) exposure.
Cherry Report
very low, non-thermal levels of RF/MW radiation alters the basic biochemistry of cells which have a potential to cause altered brain function, carcinogenesis and impaired immune system functioning. Animal experiments show that these effects occur in living animals, including DNA breakage, cancer at many body sites, behavioural alteration, EEG change and ocular damage. Many epidemiological studies show increased risks of cancer and many other health effects with increase RF/MW exposure.
Cherry Report
Epidemiologists should look for other possible changes, including psychological depression, fatigue, sleep inefficiency, chronic feelings of jet lag, endocrine disturbances and other symptoms; all these may result from a chronically low melatonin rhythm.
EPA Reports
some degree of increased risk of childhood leukemia, adult brain cancer, Lou Gehrigs Disease, and miscarriage.
Sacramento Bee
(2002)
California's female teachers have sharply higher rates of a host of cancers, including breast, endometrial female teachers found: Study findings: A study of cancer in California'sand ovarian cancer, than women of the same age and race statewide, scientists will announce today.
* 72 percent higher rate of endometrial cancer than women of comparable age and race. * 59 percent higher rate of melanoma. * 51 percent higher rate of breast cancer. * 47 percent higher rate of lymphoma. * 47 percent lower rate of cervical cancer. * 34 percent lower rate of lung cancer. * 28 percent higher rate of ovarian cancer. * 28 percent higher rate of leukemia. Source: California teachers' cancer study
Human cancer cells grow at a rate of 1600% and become more malignant.
clean
dirty
incandescent lights
(~80%)
MODELING OF INDUCED CURRENT INTO THE HUMAN BODY BY L.F. MAGNETIC FIELD FROM EXPERIMENTAL DATA
R. Scorretti Ecole Centrale de Lyon, 36 av. Guy de Collongues, 69134 Ecully, France URL : http://cegely.ce-lyon.fr
Research
Research
Dave Stetzer, Power Quality Expert, Stetzer Electric, Wisconsin Dr. Martin Graham, Professor Emeritus, U.C. Berkeley, California Dr. Donald Hillman, Professor Emeritus, Michigan State University Dr. Magda Havas, Professor Trent University, Peterborough,
Canada
Dr. Art Hughes, Ph.D., Electrical Engineering, Texas Dr. Yuri Gregoriev, Ph.D., M.D., Moscow, Russia Dr. NikitinaValentina, Doctor of Medicine, Saint Petersburg,
Russia
Dr. Vitaly Resnik, Ph.D., Republic of Kazakhstan have spearheaded worldwide research with numerous researchers on the effects of electrical pollution on humans
Solutions
Five-Wire Solution
50% lower
40% lower
hot wires
neutral
hot wires
neutral
Side View
Front View
The Health Department of the Republic of Kazakhstan has stated that any reading on this meter exceeding 50 is unacceptable and steps must be taken to lower such readings.
Unfiltered Environment
Here a woman is standing near a wall. The electric component measures 3 V/m. No Graham-Stetzer Filter is plugged in.
A Filtered Environment
A Graham-Stetzer Filter is plugged into the wall The electric component immediately dropped to 2 V/m Shortly, the electric component read 0 V/m
Unfiltered Homes
Filtered Homes
56 mV 1.7 kHz
39 mV 0.8 kHz
Filtered Schools
Etobicoke School of the Arts in Toronto
36 mV 12.5 kHz
9 mV 1 kHz
Several Graham-Stetzer filters were plugged-in nearby PCs in the library at the time. The reading on the Microsurge meter was 28 GS Units.
Cooperative Effort
1. The solution to this problem requires a cooperative effort. Utilities need to update their outdated distribution systems to meet todays technological loads. Consumers need to reduce the amount of RF they are putting on electrical wires.
2.
3.
Questions
Can we enjoy the benefits of electricity? Can we use it safely?
Is the technology available to accomplish this? Can we achieve it with minimum expense?
YES
Healthy Stem Cells are not Cancer Stem Cells Successful Cancer Treatment requires an understanding of Stem Cells
The problem is, when we treat cancer cells with chemotherapy, the cancer stem cells are being stimulated to grow too. When we take mesenchymal stem cells and mix them with tumor cells, the tumors grow much more quickly in animals.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Max Wicha hopes cancer treatments can avoid general chemo altogether and just use targeted therapies against the stem cells. Max Wicha is coming to Pittsburgh today to deliver a startling message. Standard cancer treatments not only often fail to eradicate cancer, but can make it worse. That argument isn't coming from a fringe proponent of alternative medicine, but from the founder of the University of Michigan's Comprehensive Cancer Center and a pioneer in research on why cancers recur and spread to other parts of the body.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Adult stem cells exist in most tissues, and go into action to repair damage from wounds or infections. In cancer, they can mutate and no longer obey normal bodily signals to stop growing, Dr. Wicha said. He and other researchers say that even when chemotherapy and radiation cause tumors to shrink dramatically, these stem cells can stay alive, living under the radar until they are once again spurred into action.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Retraction
(cont.)
Our work does suggest that the resistance of a small population of tumor cells to these treatments may account for some of their limitations. Based on this, we are working to develop new approaches to target this specific cell population -- treatments that could augment chemotherapy and radiation therapy. New treatments based on this theory are in their early testing stages. Only through the conduct of rigorous clinical trials will we be able to determine whether addition of these new therapies improves the outcome for patients with cancer. In the meantime, patients diagnosed with cancer need to follow their doctors' recommendations for treatment according to the current standards of care and inquire whether they are eligible for a clinical trial. MAX WICHA, M.D. Distinguished Professor of Oncology Director, University of Michigan Comprehensive Cancer Center Ann Arbor, Mich.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Chemotherapy increases numbers of dangerous cancer STEM cells by increasing cytokines like IL-8 so that cancer stem cell cannot differentiate *, which cause treatment resistance. The Goal is to combine chemotherapy with adjunctive therapies which prevent increase of cytokines (like IL-8) when tumors are attacked with chemotherapy or radiation (and IPT). BUT: If they would differentiate, they would become susceptible to chemotherapy again. THEREFORE: The highest goal of Corrective Cancer Care is to re-educate the cancer STEM cells so they redifferentiate and stop creating cancer TUMOR cells.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
What is Cancer?
Cancer is understood to be unregulated cells proliferating autonomously within the human being either in humoral or tumorous form. (Query: Are these aggressive or confused cells?)
What is a Tumor?
A tumor, benign or malignant, is a proliferation of cells of which, in the case of a malignant cancer, less
Is attacking cancer the best strategy? The ideal strategy whereby one could win without fighting, accomplish the most by doing the least, bears the characteristic stamp of Taoism.
- note by Thomas Cleary, translator, of Sun Tzus The Art of War
Similarly, usually less than 1% of primary tumor cells cultured in vitro can give rise to colonies.
Diehn, M Therapeutic Implications of the Cancer Stem Cell Hypothesis Semin Radiat Oncol. 2009 April; 19(2): 7886.
What metastasizes?
Stem cells!
tumor cells are heterogeneous in their capacity to give rise to tumors upon transplantation or to form colonies in culture assays. For in vivo tumor transplantation, this is reflected in the large numbers of tumor cells that must usually be transplanted to form a tumor. For primary human and mouse tumors, this number often resides in the thousands or millions. (ibid Diehn et al)
Chemotherapy and Radiation is only effective in non-aggressive cancer cells (tumor cells, not cancer stem cells).
Invasive Carcinoma
Chemo-Therapy Radiation
Linheng Li and William B. Neaves Cancer Res 2006; 66: (9). May 1, 2006
Resistence!
Normal cell
Example of Chemotherapy Worsening Cancer: Cytokines which inhibit Stem Cell Differentiation are increased by doxorubicin inH460 tumor cells, In vitro
Int J Cancer, 2009, NIHPA
Levina et al. Chemothera peutic drugs and human tumor cells cytokine network. Int J Cancer. 2008
Going Forward
Assessing the efficacy of such treatments will require the advent of new approaches to assessing CSC frequency and viability within tumors. Furthermore, classic mechanisms of treatment resistance, such as clonal selection and the tumor microenvironment, will continue to present obstacles for achieving cure. It is therefore likely that combinations of cytotoxic, biologic, and CSC-directed therapies will ultimately allow the largest possible improvements in patient outcomes.
But.
IPT, being chemotherapy (albeit low dose and targeted kinder and gentler) nevertheless still worsening cancer prognosis since it still kills ONLY cancer tumor cells (not the cancer stem cells): the resulting IL-8 SOS signal still goes out to muster reinforcements from the mesenchymal stem cells which increase the number and virulence of cancer stem cells.
King Lear
and his loving loyal 3rd daughter
Cordelia
(cont.)
The goal of the Cordelia Effect (Corrective Cancer Care) is to control the variables including the local tumor environment so as to shift the cancer stem cells metabolism away from proliferation and towards differentiation, in order to decrease tumor size, growth and virulence.
Proteolytics Enzymes
Tumors are wounds, that do not heal. Every cancer medication should improve wound healing.
- Rudolph Virchow, 1865
Today we know that cytokines (inflammation) inhibit cell differentiation and wound healing.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Anti-Inflammatory Agents
Goal: To interrupt the IL-8 cytokine SOS and allow differentiation of cancer stem cells
Reprotaxin -CXCR1 receptor blocker- (Wicha) Oxygen (hypoxemia stimulates CSCs) Tumeric, Resveratrol, Brown Seaweed, MEBO Gastro Intestinal Complex (GIC) Fermented Soy (Haelan 951)
In leukemic Children increases a) transplant efficiency and b) reduces hospital stay of children
4 month with Conventional transplantatio n 1 1/2 month if treated with Dramatic increase of fermented soy Hospital Stay of Children cell differentiation!
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Serum TNF-a
(pg/ml)
50 40 30 20 10 0
Nach Einnahme
-5
10
15
20
25 Zeit (Wochen)
ote: in the Blood Circulating Tumor Cells are more aggressive than the primary tumor : Less Differentiated !!!!!
Rohr et al 2010
facher Anstieg
Single cases
100 100
0 0 0 0
1,5 1,5
3 3
Single Cases
Single Cases
Ovary Ca
untreated With fermented soy
Cachexia kills Cancer Patients BUT Fermented Soy saves Cancer Patients
N= 164 N= 78
Chemotherapy + Placebo
Fermented Soy transforms Resistant Cancer Stem Cells into differentiated cancer cells which can then be treated with Chemo or Radiation therapy.
Cancer Stem Cell Differentiating
Primary
Invasive Carcinoma
Mets
Chemotherapy
Radiation
Fermented soy transformed circulating cancer stem cells (in vivo, human) into more differentiated and therefore more targetable treatable cancer tumor cells. This mechanism may be the reason for dramatic increase in survival we see in clinic. An example of the Cordelia Effect
Greater Celandine
- an important component
The anti-tumor properties of extracts from the wart plant were first recorded in a medicinal herb book in 1536.
(cont.)
6) IPT, while kinder and gentler, must not be given unless adjunctive care is taken to minimize cancer stem cell stimulation 7) Adjunctive treatment modalities represent a significant improvement over traditional IPT.
8) This is a therapeutic message which our patients, as well as our oncology colleagues, are ready to hear.
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
Sirens sang from Science rocks and caught my ear, despite the plug nestled deep of orthodox which churches plant, so proud and smug. Orphans each adrift we are; homeless, steering course by star. The winds would change, time was short. The moment asked of me resolve. So digging deep within my heart, I chose, swung prow, intent to solve the only question man must ask; the only truly human task
For the rest of the epic poem, see Appendix and http://weeksmd.com/?p=5456
The Weeks Clinic for Corrective Medicine and Psychiatry 2011
The Standard of Care is subtherapeutic. Only 10% of conventional oncologists say they would take the medication they prescribe if they had cancer. In contrast, 100% of IPT doctors would take their own medicine!
BSW (c) 2011
The longest continuous cancer chemotherapeutic protocol in the western hemisphere (1926-present)
BSW (c) 2011
insulin-sensitive receptors on human cancer cells causes predominance of insulin effect in cancer cells, sparing normal host tissues = INCREASED SAFETY
Synergy of insulins membrane and metabolic effects enhances anticancer drug action in cancer cells BSW (c) 2011 = INCREASED EFFICACY