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Learning Objectives
Participants will be able to
Describe normal cardiac function Describe and differentiate types of shock Discuss the significance of cardiac rate and pressure parameters Discuss appropriate medical and surgical management of the patient in shock
John
50 year old traffic accident victim
Awake, moderate distress, c/o chest pain & SOB PMH: Hypertension, diabetes. SH: ppd cigarettes, taxi driver Exam: HR 120, BP 80/40. PERRLA. Lips cut. Heart irregular. Chest has wet crackles. Abdomen tender.
What is the clinical syndrome? What could be the underlying diagnoses? Why? What do you do? Why?
Shock
Insufficient circulation of oxygenated blood to meet metabolic demands.
Shock
Hypovolemic Cardiogenic
Obstructive
Distributive
Shock
Hypovolemic
Hemorrhage Aortic dissection Anemia
Cardiogenic
Decompensated CHF Acute coronary syndrome Dysrhythmia
Bradycardia Tachycardia Fibrillation
Obstructive
Aortic valve stenosis
Distributive
Sepsis Thyrotoxicosis Shunt syndromes
Typical 70 kg adult
70cc/cycle X 70 cycles/min 4900 cc/minute
Afterload
Due to systemic vascular resistance (SVR)
Contractility (inotropy)
Blood pressures
CVP
Central venous pressure Right ventricular preload
Blood pressures
PAOP
Pulmonary artery occlusion pressure RV output LV preload
Left Ventricular End Diastolic Pressure (LVEDP)
Blood pressures
MAP
Mean Arterial Pressure MAP =DBP +(PP/3) MAP = CO x SVR
?
?
Preload
Inotropy
Shock
MAP = (SV x HR) x SVR
Afterload
?
What types of shock will affect each of the cardiac parameters?
Hypovolemic Hemorrhage Anemia Cardiogenic CHF ACS Dysrhythmia Valve Dz Cardiac tamponade Distributive Sepsis Thyrotoxicosis Shunt syndromes Obstructive Aortic valve stenosis
Preload
Inotropy
Shock
MAP = (SV x HR) x SVR
Afterload
Hypovolemic Cardiogenic Low CVP Low CO High SVR High CVP Low CO High SVR Distributive Obstructive Low CVP HIgh CO Low SVR Low CVP Low CO +/- SVR
Quadrad 4:
Temperature , HR, BP, Respirations
Quadrad 5:
Tank (volume) Tank (resistance) Pump (inotropy) Rate
Quadrad 3:
Oxygen, IV, Monitor, Fluids
Acute shock
Volume
Pump
Resistance
Rate
Bradycardia? Tachycardia?
Hypovolemic shock
Dehydration
Emesis and diarrhea Environmental losses (perspiration)
Hemorrhage
Traumatic
External, Internal
Gastrointestinal malignancy, ulcer, varices Obstetric or gynecologic previa, ectopic, cyst Vascular rupture of AAA Pulmonary PE, cavitary tuberculosis
Classification of hemorrhage
Class Parameter I II III IV
<750 <15%
7501500 1530%
<100
>100
>120
>140
Normal Decreased Decreased Decreased 1420 >30 2030 2030 3040 515 Confused >35 Negligible Lethargic
Normal Anxious
Volume restoration
IV crystalloid
Saline Ringers lactate
Transfusion
If no response to 2 Liters of crystalloid If Class III hemorrhage Critically ill pt with Hb < 8
If no T&C available
O pos males O neg females
Cardiogenic shock
Causes
Acute coronary syndrome Myocarditis Acute valve disease Pulmonary embolism Pericardial tamponade Dysrhythmia
Bradycardia Tachycardia
Killip stages
I. No heart failure, no signs of decompensation II. Heart failure, rales, S3 gallop, pulmonary venous hypertension III. Severe heart failure, frank pulmonary edema, rales throughout lung fields IV. Cardiogenic shock, hypotension (SBP <90mmHg), peripheral vasoconstriction with as oliguria, cyanosis and diaphoresis
PA catheterization?
PAC not needed to dx heart failure or shock
PAC may help differentiate cardiogenic vs non-cardiogenic shock
Pulmonary Edema?
Volume Problem?
Administer Fluids Transfuions? Cause-specific interventions Vasopressors (?)
Pump Problem?
Rate Problem?
Norepinephrine
Dopamine
Dobutamine
Nitroglycerin OR Nitroprusside
Adapted from: ALCS Resource Text. Dallas, TX: American Heart Association, 2008.
Distributive shock
High-output heart failure
CO unable to match systemic demand
Thyrotoxicosis Anemia
Obstructive Shock
Resistance to cardiac outflow
afterload, but SVR and MAP
Obstructive Shock
Aortic stenosis
Angina, DOE, exertional syncope SEM initially, softens w/ progressive stenosis Diagnosis suspected on exam, ECG, CXR Echo vital for definitive diagnosis
Management
Avoid reductions in MAP (avoid hypotension) Correction requires surgery
MAP = (SV x HR) x SVR
In conclusion
Systematic approach (ABCs, 5 quadrads) 4 classes
Hypovolemic Cardiogenic Obstructive Distributive
Preload
Inotropy
Afterload
Resources
Executive summary of the guidelines on the diagnosis and treatment of acute heart failure. Eur Heart J. 2005 Feb;26(4):384. (http://eurheartj.oxfordjournals.org/cgi/content/full/26/4/384) Rogers J. Cardiovascular Physiology. Updates in Anaesthesia. 1999 (Issue 10): 1-4. (http://www.nda.ox.ac.uk/wfsa/html/u10/u1002_01.htm) (accessed 8 December 2008) ALCS Resource Text. Dallas, TX: American Heart Association, 2008. Gutierrez G, Reines HD, Wulf-Gutierrez ME. Clinical review: hemorrhagic shock. Crit Care. 2004 Oct;8(5):373-81. Epub 2004 Apr 2. PMID: 15469601 Committee on Trauma. Advanced Trauma Life Support Manual. Chicago. American College of Surgeons, 1997: 103 112. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease. J Am Coll Cardiol. 2006 Aug 1;48(3):e1-148. (http://content.onlinejacc.org/cgi/content/full/48/3/e1)
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