Académique Documents
Professionnel Documents
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By
Prof. J.T. Anim
Department of Pathology
Lecture I
Topics
Nomenclature
Definitions
Classification of neoplasms
Benign vs. malignant neoplasms
Characteristics of neoplasms
Grading of malignant neoplasms
Neoplasia - Terminology
neo = new, plasia = growth
Tumour = swelling
Cancer = ‘crab’
Desmoplasia = stimulation of
excessive connective tissue (collagen)
formation by parenchyma cells
Neoplasia - Nomenclature
Benign neoplasms = ….oma eg. fibroma, lipoma, adenoma
(exceptions: melanoma, seminoma, lymphoma)
Malignant neoplsms
Mesenchymal: …..sarcoma
Epithelial: …..carcinoma
Divergent differentiation of parenchymal cells – mixed
tumour eg. pleomorphic adenoma of salivary gland.
Neoplasm from more than one germ layer – teratoma
Combination
Morphological pattern of
tumour growth
Progressive impairment of
differentiation leads to carcinoma in
situ