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CASE ANALYSIS
Objectives:
CASE ANALYSIS
P. B. Casuela, Jr.,MD
Case 1 :
1 cm
A B C D
A (forearm) B (elbow)
1. Characterize the following and correlate with the gross clinical
presentation demonstrated from the previous slide.
A B
9. State common
complication of
these lesions.
2. State readily available
diagnostic
procedure/s which
could be under-
taken in this case.
State principles.
3. Localize (layer of skin)and
characterize the following
skin lesions
and
which lesion is compatible
with the clinical
presentation.
B
4. Match and describe the microscopic
features of three diseases one
of which could be present in this
patient and relate it to com- A
mon clinical presentation. 4x
!. Herpes simplex infection
2. Bullous pemphigoid
3. Pemphigus vulgaris
B4x 40x C 4x
4.
1. Herpes simplex
-Intraepidermal vesicle with multinucleated giant cells echibiting the
“Moulding phenomenon”=nuclei deform each other and never ovarlap
one another.
2. Pepmphigus vulgaris
- intraepidermal, suprabasal cleft or blister containing acantholytic cells (inset)
3. Bullous pemphigoid
-non-acantholytic, subepidermal blister with prominent eosinophilic cell infiltrates
20x: A B
1cm
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