THIRD EDITION

HUMAN PHYSIOLOGY
AN INTEGRATED APPROACH Dee Unglaub Silverthorn, Ph.D.

Chapter 3, part B
Cells and Tissues

PowerPoint Lecture Slide Presentation by Dr. Howard D. Booth, Professor of Biology, Eastern Michigan University
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Golgi Apparatus

Protein packaging Secretory vesicles Secreted to E C F

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Golgi Apparatus

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-11: The Golgi apparatus

Cytoplasmic Vesicles
Lysosomes
Enzymes Intracellular digestion Peroxisomes Hydrogen peroxide Detoxification Fatty acid degradation
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-12: Lysosomes and peroxisomes

Nucleus
Nuclear envelope

Nuclear pore complex

Chromatin DNA form genes Nucleoli DNA concentrations

Control RNA synthesis

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Nucleus

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-13: The nucleus

Primary Tissue Types

Tissue defined:

Matrix
Tissue types Epithelial Connective Muscle

Nervous

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Junctions
Cell to cell

Gap junction
Tight junction Anchoring junction Cell to matrix Focal adhesions

Hemidesmosomes

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Junctions

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-14: Types of cell junctions

Key Junction Proteins: Connexin, cadherins, occludin & integrins

Figure 3-15: A map of cell junctions

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Epithelial Tissues

Defined:
Types: Exchange

Transport
Ciliated Protective

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Epithelial Tissues

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-17: Distribution of epithelia in the body

Exchange Epithelial Tissues

Leaky junctions Rapid transport Oxygen Carbon dioxide

Ions & fluids

Capillaries Lung alveoli
Figure 3-18a: Movement of substances across tight and leaky epithelia
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

More Epithelia
Transport epithelium Intestinal microvili Tight junctions Ciliated epithelium Trachea Sweep mucous out Protective epithelium Skin Multiple cell layers Prevent exchange
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-18b: Movement of substances across tight and leaky epithelia

More Epithelia

Ciliated epithelium Trachea Sweep mucous out Protective epithelium

Skin
Multiple cell layers Prevent exchange
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-19a: Ciliated epithelia

Secretory Epithelia

Exocrine tissues Mucous glands- goblet cells Sweat glands Secreted externally

Endocrine tissues
Hormones Secreted to ECF & blood
Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Secretory Epithelia

Figure 3-20: Goblet cells

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Secretory Epithelia

Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings Copyright 2004 Pearson Education, Inc., publishing as Benjamin Cummings

Figure 3-21: Development of endocrine and exocrine glands from epithelium