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Outline
Tissues, organs, organ systems
4 types of tissues Organs consist of multiple tissue types Organ systems are groups of organs that function together
Thermoregulation
Feedback loops
4 Types of Tissues
When cells with the same characteristics or specializations are grouped together, they form a type of tissue
Epithelial Connective Muscle Nervous
Epithelial Tissue
Covers the body and lines organs Sheets of densely packed, tightly connected cells that cover surfaces Comprise the skin and line hollow organs (gut) Some epithelial cells are secretory (hormones, mucus, sweat, digestive enzymes)
Connective Tissue
Support and reinforce other tissues Dispersed populations of cells embedded in an extracellular matrix comprised of proteins
Collagen (25% total body protein) Elastin (wrinkles with aging)
Adipose Tissue
Stored energy
Blood
Muscle Tissue
Contract and cause movement Elongated cells Most abundant tissue type When active (contracting) use most of the energy produced by the body
Nervous Tissue
Process information Neurons communicate via electrical and chemical signals Glial cells support neurons (outnumber them too)
Organs
Consist of multiple tissue types Ex. Wall of stomach
Inner surface lined with epithelial cells that secreted mucus and digestive enzymes Connective tissue underneath epithelial lining Muscle tissue (smooth) allows stomach to contract Neurons control contractions and secretions
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Organ Systems
Controlled and regulated to achieve constancy in the internal environment of the organism.
Nervous Endocrine Muscles Skeletal Reproductive Digestive Respiratory Circulatory Lymphatic Immune Skin Excretory
Pancreas
Adrenal cortex Adrenal medulla Kidney Silverthorn, Human Physiology, 3rd edition Figure 7-2 Skin Gonads
Homeostasis
Single-celled organisms meet all of their needs by direct exchange with the external environment Evolution of an internal environment, distinct from external environment, made multi-cellular organisms feasible Homeostasis allows for conditions of internal (intracellular) environment to remain constant and optimal even when the external environment fluctuates
Intracellular fluid
Intracellular fluid
Protective cells
ECF is the interface between the external environment and the cells
Stratton with permission
Homeostasis cont.
Homeostasis depends on the ability to regulate the activities of organs and organ systems to keep the internal environment constant Generally, activities of organs/organ systems are controlled by the nervous and endocrine systems
Claude Bernard
He recognized that an animals independence from changing external conditions is related to its capacity to maintain a relatively constant Internal environment.
Silverthorn,
3rd
ed.
Walter Cannon
Recognized that the key to maintaining a relatively stable internal environment is the presence of regulatory mechanisms in the body.
He coined the term homeostasis to describe the maintenance of this stable internal environment. homeo = similar, stasis = state
Walter Bradford Cannon (1871 - 1945)
Temperature
External temps vary enormously Living cells can function over a narrow (tolerable) range of temps (0-45C) Q10 is a measure of temp sensitivity
Q10 = RT/RT-10
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Energy Budgets
Both ectotherms and endotherms can alter their body temperature by altering 4 characteristics of heat exchange b/t their bodies and the environment
Radiation Conduction Convection Evaporation
Heatin
Metabolism + Rabs
Heatout
Response Loops
Stimulus
Sensor
Afferent Path
Integrating Center
Efferent Path
Effector
Response
Sensor
Afferent Path
Integrating Center
Efferent Path
Effector
Response
Thermoregulation in Endoderms
Thermoneutral zones and basal metabolic rates Basal metabolic rates are related to body size Endotherms respond to cold by producing heat
Shivering heat production Nonshivering heat production
Shivering
Depends on contractile machinery of skeletal muscles to consume ATP Tremor results Conversion of ATP to ADP results in heat production
Regulatory Thermostat
Controls thermoregulatory adaptations and mechanisms (shivering) Integrative center is in hypothalamus, which establishes a temperature set point and receives feedback information Temperature of external environment is sensed by skin sensors (feedforward)
Hypothalamus
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