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CPR in Microgravity
Basic Life Support
Simon N Evetts PhD
Thais Russomano MD PhD
John Ernsting MBBS PhD
Subhajit Sarkar MRCS
Lisa Evetts RGN
João Castro MD
Microgravity Laboratory, PUCRS, Porto Alegre, Brazil.
Human Physiology and Aerospace Medicine Group, King’s
College London.
Introduction
Non-terrestrial as opposed to microgravity.
Introduction
Non-terrestrial as opposed to microgravity.
Basic Life Support;
Introduction
Non-terrestrial as opposed to microgravity.
Basic Life Support;
– Cardiopulmonary Resuscitation without equipment
or other resources.
Introduction
Non-terrestrial as opposed to microgravity.
Basic Life Support;
– Cardiopulmonary Resuscitation without equipment
or other resources.
Introduction
Non-terrestrial as opposed to microgravity.
Basic Life Support;
– Cardiopulmonary Resuscitation without equipment
or other resources.
Single rescuer, not multiple care-giver.
Introduction
Non-terrestrial as opposed to microgravity.
Basic Life Support;
– Cardiopulmonary Resuscitation without equipment
or other resources.
Single rescuer, not multiple care-giver.
Emphasis on chest compression, mouth-to-
mouth ventilation secondary consideration.
The Space Environment
Space exploration is inherently dangerous.
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Significant Space Related
Medical Occurrences
Year Mission Nation Event
1967 Soyuz 1 USSR Spacecraft crashed – 1 death
1967 Apollo 1 US Command module fire – 3 deaths
1969 Apollo 11 US Type 1 decompression sickness
1970 Apollo 13 US Urinary tract infection
1971 Soyuz 11 USSR Depressurization – 3 deaths
1971 Apollo 15 US Arrhythmia during lunar EVA
1975 Apollo 18 US Nitrogen tetroxide pneumonitis
1985 Salyut 7 USSR Prostatis and sepsis
1985 Salyut 7 USSR Hypothermia
1986 Challenger US Spacecraft exploded - 7 deaths
1987 Mir Russia Arrhythmia requiring evacuation
1997 Mir Russia Depressurization after collision
1997 Mir Russia Toxic atmosphere after fire
2003 Columbia US Spacecraft disintegrated – 7 deaths
Pulseless victim
The Space Medicine Configuration Control Board of NASA
has approved a list of 442 medical conditions (the Patient
Condition Database) that appear possible during long
duration spaceflight on the ISS.
Pulseless victim
The Space Medicine Configuration Control Board of NASA
has approved a list of 442 medical conditions (the Patient
Condition Database) that appear possible during long
duration spaceflight on the ISS.
Of these conditions 106 (24 %) are classified as “critical”
requiring use of critical care procedures.
Pulseless victim
The Space Medicine Configuration Control Board of NASA
has approved a list of 442 medical conditions (the Patient
Condition Database) that appear possible during long
duration spaceflight on the ISS.
Of these conditions 106 (24 %) are classified as “critical”
requiring use of critical care procedures.
…including cardiac conditions (e.g. myocardial infarction,
ventricular fibrillation, ventricular tachycardia, and asystole),
Pulseless victim
The Space Medicine Configuration Control Board of NASA
has approved a list of 442 medical conditions (the Patient
Condition Database) that appear possible during long
duration spaceflight on the ISS.
Of these conditions 106 (24 %) are classified as “critical”
requiring use of critical care procedures.
…including cardiac conditions (e.g. myocardial infarction,
ventricular fibrillation, ventricular tachycardia, and asystole),
…and respiratory conditions (e.g. acute airway obstruction,
laryngeal oedema from anaphylaxis and inhalation injuries).
Pulseless victim
It has been estimated that the risk to an ISS crew member of
developing a serious medical condition requiring medical
evacuation is 6% per year*,
* Johnston, S. L., Marshburn, T. H., and Lindgren, K., 2000. Predicted Incidence of
Evacuation-Level Illness/Injury During Space Station Operation. 71st Annual Scientific
Meeting of the Aerospace Medical Association, Houston, Texas. May 2000.
Pulseless victim
It has been estimated that the risk to an ISS crew member of
developing a serious medical condition requiring medical
evacuation is 6% per year*,
… and 1% per year risk of a life-threatening condition*.
* Johnston, S. L., Marshburn, T. H., and Lindgren, K., 2000. Predicted Incidence of
Evacuation-Level Illness/Injury During Space Station Operation. 71st Annual Scientific
Meeting of the Aerospace Medical Association, Houston, Texas. May 2000.
Pulseless victim
It has been estimated that the risk to an ISS crew member of
developing a serious medical condition requiring medical
evacuation is 6% per year*,
… and 1% per year risk of a life-threatening condition*.
A figure of 0.15%/yr of CAD related event occurring in 35-
45 yr old flight personnel has been cited**.
* Johnston, S. L., Marshburn, T. H., and Lindgren, K., 2000. Predicted Incidence of
Evacuation-Level Illness/Injury During Space Station Operation. 71st Annual Scientific
Meeting of the Aerospace Medical Association, Houston, Texas. May 2000.
** Ball, C.G., Hamilton, D.R. and Kirkpatrick, A. 2004. Primary prevention approach to
mitigating cardiac risk in astronauts. 75th Annual Scientific Meeting of the Aerospace
Medical Association, Houston, Anchorage. May 2004.
Pulseless victim
As has the figure of 0.06 persons/year with regards to the risk
of a healthy astronaut receiving a significant injury or
developing a significant medical condition in space*.
* Mukai, C. and Charles, J. B. 2004. Psychological and medical challenges for Mars
crew composition as considered against similar challenges faced by the Lewis and Clark
Expedition. 75th Annual Scientific Meeting of the Aerospace Medical Association,
Houston, Anchorage. May 2004.
Pulseless victim
As has the figure of 0.06 persons/year with regards to the risk
of a healthy astronaut receiving a significant injury or
developing a significant medical condition in space*.
The potential for a serious medical incident resulting in a
pulseless apneic state requiring intervention, therefore is real.
* Mukai, C. and Charles, J. B. 2004. Psychological and medical challenges for Mars
crew composition as considered against similar challenges faced by the Lewis and Clark
Expedition. 75th Annual Scientific Meeting of the Aerospace Medical Association,
Houston, Anchorage. May 2004.
Recent and current CPR
guidelines (+1Gz)
European Resuscitation Council 1998:
– Mouth-to-mouth ventilation requiring tidal volumes of
400 – 600 ml.
– Chest compression depth of 40 – 50 mm.
– Chest compression rate of ~ 100 compressions.min-1.
Recent and current CPR
guidelines (+1Gz)
European Resuscitation Council 1998:
– Mouth-to-mouth ventilation requiring tidal volumes of
400 – 600 ml.
– Chest compression depth of 40 – 50 mm.
– Chest compression rate of ~ 100 compressions.min-1.
European Resuscitation Council 2001:
– Tidal volumes of 700 – 1000 ml.
– Chest compression depth of 40 – 50 mm.
– Chest compression rate in excess of 100 min-1.
+1Gz - Earth
Chest Compression Depth
According to Rescuer Body Weight
Earth
Earth GravityGravity
(9.8 ms-2)
Big patient/low 9.8 m.s-1
β +2 s.d., β +1s.d.,
Average
Mean compliance chest
β -1s.d.,
1000
compliance chest γ +2 s.d. γ +1s.d. γ -1s.d.
700
6.1 76 kg person
600 Min required
(N)
Force (N)
500
depth
Force
Compression
Com pression Depth
depth (cm )(cm)
+0.16 Gz - The Moon
+0.16 Gz - The Moon
Chest Compression Depth
According to Rescuer Body Weight
Lunar Gravity (1.62 ms-2)
Lunar Gravity
β +2 s.d., β +1s.d., β -1s.d.,
Mean
1000
γ +2 s.d.
Average compliance chest
γ +1s.d. γ -1s.d.
900
800
700
600
(N)
Force (N)
500
Force
γ -2 s.d.
Minimum required
200
depth (3.8 cm) 93 kg
2.0
1.7 76 kg
100
1.0
0 41 kg
0 1 2 3 4 5 6 7 8 9 10 11
900
800
700
600
(N)
(N)
Small patient/high
Force
400
3.7 93 kg
300 3.2
β -2
76 kg
s.d.,
200 γ -2 s.d..
2.0
Minimum 41 kg
100
required depth
0
0 1 2 3 4 5 6 7 8 9 10 11
Com pression depth (cm )
Compression Depth (cm)
Mean Mass Rescuer – Mean Chest
Compliance Patient
76 kg provider - Mean compliance chest - Different gravities
1000 76 kg Rescuer
900
800
6.1
On Earth
700
600
Force (N)
Force (N)
500
400
0
0 1 2 3 4 5 6 7 8 9 10 11
Com pression depth (cm )
Compression Depth (cm)
What can be done about off
planet BLS?
Assisted CPR.
– Using a restraint system.
What can be done about off
planet BLS?
Assisted CPR.
– Using a restraint system.
What can be done about off
planet BLS?
Assisted CPR.
– Using a restraint system.
– Using assistance devices.
What can be done about off
planet BLS?
Assisted CPR.
– Using a restraint system.
– Using assistance devices.
– Multiple person CPR.
What can be done about off
planet BLS?
Technique of Equipment Description
compression
Chest Comp Rate 80.2 ± 3.4 98.3 ± 6.3 89.3 ± 4.1 ~ 100
(per min)
Chest Comp Rate 80.2 ± 3.4 98.3 ± 6.3 89.3 ± 4.1 ~ 100
(per min)
Chest Comp Rate 80.2 ± 3.4 98.3 ± 6.3 89.3 ± 4.1 ~ 100
(per min)
Chest Comp Rate 80.2 ± 3.4 98.3 ± 6.3 89.3 ± 4.1 ~ 100
(per min)
Chest Comp Rate 80.2 ± 3.4 98.3 ± 6.3 89.3 ± 4.1 ~ 100
(per min)
Chest Comp Rate 80.2 ± 3.4 98.3 ± 6.3 89.3 ± 4.1 ~ 100
(per min)
Any questions?
E-mail address
simon.n.evetts@kcl.ac.uk