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2 " 4
= ϕ6 θ7 2" " 4
θ " 3 2 " "
/ 16 7 ?

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H :$$$ 4 4
@H :$$$ 4
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! 2 " "
4 " "
$

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:
δ "
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6:;7
=:

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$

8 " "
6R" $ ;AA&7 2" " " +
1 " $

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6θ θ #7 =
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" " 4 2 " " " / <2 " 4 4 "

4 8 / " 4 " 4 " 05
4 $ 2 " 4 6 8 6:7+6(77$
<" " " 05 9
D 6 9D7 " 4 6 /
7 D ! " 6D! 7
60 $ :));7 " " " 4 6 8 6'7+ x 10
-4 Estimated and Real Specific production kinetics
8
6G77? Estimated Output
7 Real Output

:$ P 6AT
6
4 7$

Specific production kinetics

;$ P 2 " ;(AT " 4 5

4/ (T " 4
4 $
3

<" " 4 62 " 2

/ 4 7 A$A: 6 F 7$
1

$, 0

-1
/ " " " 0 100 200 300 400 500 600 700 800 900 1000
Time (Min)
4 " / 2 4
" 2 $ / " 4 4 2 " '? ! 6 7 6
" 4 6C7 7 $
" 2" " 2 > ($
4 " " " $-
4 6 U A$))7$ "
4 4 $ <" 4 4/ 4 " 4 6
" 1 " / 4 7 8 3/ 4/ " 05
4 6 &7 " 2 < 4 $ 2 (T " 2
4/ " " $ <" ;(AT "
4 " " 2 /
" 2 " 4 / "
" "
" "
/ $ " 2 B
G )$ <" 4 3 "
3 E" 4

>? ! 6 7 6
7 4

B? ! 6 7 6
7 4

(? ! 6 7 6
7 2" $
 1δ
Estimated and Real Specific growth kinetics "
0.14 < 4 " / " 2
Estimated Output
Real Output
" E" D; D; $
µ
0.12
4 " " &$

0.1
Specific growth kinetics

1δ
"
< 4 ;? ! /
0.08
4 $
0.06

0.04
δ "
µ β
A$AA;A A
0.02 ;
A$AA:; A
;
0
0 100 200 300 400 500 600 700 800 900 1000
Time (Min)
A A$:&::
&

G? ! 6 7 6
7 2" $ ! " "
4 " 2 :A :: :;$ <"
x 10
-4 Estimated and Real Specific production kinetics " " 4
8
:AA >AA 6 7 2" " "
Estimated Output
7 Real Output
4 2 "$
6 -3
x 10 Parameter Sensitivity for CO2 output
Specific production kinetics

6
5
mu parameter
beta parameter
4
5

3
4
Sensitivity Functions

1
3

0
2
-1
0 100 200 300 400 500 600 700 800 900 1000
Time (Min)
1
)? ! 6 7 6
7 $
0
0 100 200 300 400 500 600 700 800 900 1000
Time (Min)

+ &$"."/"
'"$) & ') " :A? P / D; $

" / 1 " "

-3
" 2 x 10 Parameter Sensitivity for O2 output
3.5
" 2 1 ? mu parameter
beta parameter
3

∂ 6 θ + ∆θ 7 − 6 θ 7
≈ 6:&7 2.5
∂θ ∆θ
Sensitivity Functions

" 4 ∆θ 2 2

" 1.5

1 $ <"
1
2 / ; ; & "
3 S E$ # " / 12 0.5
" ?
0
0 100 200 300 400 500 600 700 800 900 1000
Time (Min)

∂ ; ∂ ; ∂ ; ∂ ; ∂ & ∂ & ::? P / D; $

6:>7
∂µ ∂β ∂µ ∂β ∂µ ∂β
 Parameter Sensitivity for GA3 output
0.25
mu parameter
3 2 ? <" " 2 3 3 2
beta parameter " " 6 D5 % L<+
0.2 :A>A;AG7$
Sensitivity Functions

0.15

$ 4 $ <" 4 W$ M %$ :)))
" < /+0 1 5 5 2 3
0.1
" % ! ;&?(':+('>$
0 !$ W 0 " !$ :)); X9
2 3 2 "
0.05
/ / Y W
((6:7?:)&+;;>$
0
0 P$Z=[" $Z! #$P$Z @ O $ P " 9$
0 100 200 300 400 500 600 700 800 900 1000 ;AA;$ X9 4 / ! ; +
Time (Min)
/ 4 Y$ O
:;? P / & $ P " &'6:'7?>::&+>:;B$
$ 9 + P$ %$ ;AA; X
8 2 / " 2 2" & +
< 4 6 7$ Y9 0 " / &B6)7?:A&&+:A>A$
# 3 =$ ! " 4 $ O" #$ :)G) X /
2 2 3 1 Y 5
< 4 &? 4 2 5 2 3 ;?&()+&''$
$ 9 " $ M$ :)); #/4 "
1 / 4 $ 0
6θ θ #7 µ β % ;;? (>B+(('$
P " 9$ " 9$ ;AA:$ X 4 /
µ : +A$G((> / / " 8 / $: 6P\ :7Y$
β +A$G((> : O ! < " >&6B7?&;)+&&G$
<" 4 W $ 9] + P$ W 8 #$ 9$
%$ ;AAA X "/4 "
4 " " 2 4 " 1 / 4 Y 0
14 2 " 4 6V A$)(7 2 " % ;;6'7?(>B+(('$
4 8 / 8 / <" $ = $ :))> " 9
$ 9 = 2 5 5 2 3 ^
" % >A?:&;G+:&>A$
# 0 3 #$ 44 !$ # $ M /4 =$
# @ W$ :))' / "
%1 9 ! /+0 1 "%
05 " 2 @ >>? :AB:+:AG)$
2" " " 4 3 2 R" R$ $Z $M$ O $ $O $ $ ;AA&$ X%
1 / $ "/ 1
05 / " "/ F " " 8 Y$ R W$ ;?;A:*;::$
2 " " 3 2 "
3 2 " " 2 4
+ / 2 3 " 4
/ " 4 / 1 1
" 4 4 $

" 2 3 4 " "

4 $ " 05
2 " 4 "
4 " 2 $ @
2 " 4 " 3
2 $ # 2 "
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/ $ 4 / "
" 4 " 8
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" 2" 3 S "
3 E 4 " " "
4 / 4
/ 4 6 &7$