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Ion exchangers are insoluble macromolecules with ionisable groups, that have property to reversibly
exchange some of their ions to other ions coming from solution

Cationic resin : reversible exchange of cations. Its charge is negative

Resin-G- / X+ + cation+ <-> Resin-G- / cation+ + X+

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bounded to support

G- X+

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Affinity chromatography
Principle :
Stationnary phase is chemicaly inerte support, bounded to effector that has biologic affinity to
sample to analyze

1 - fixation 2 - purification 3 - elution

1 - Fixation step : the mixture of molecules containing component toisolate is loaded into column.
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3 - Elution step : purified molecule is “un-bounded” from comumn and transported by eluant

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LPLC 8% 4,5 % 2,9 % 0,4 %
Electrophoresis 1% 0,2 % 0,1 % /
Immuno-enzymo (fluorimetry) / / / 1,3 %
Immunologic(turbidimetry) 48 % 43 % 41 % 37,3 %

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Hemolytic ænemia
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Inform clinician

Evaluate glycemic balance with other


tests (fructosamines, glycemia)

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Breakfast
HbA1c
15
Fasting (nocturial period) Postprandial (daytime period)
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10

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10.0 8 - 8.9%
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8.4 7 - 7.9%
6 Morning 4.4 6.5 - 6.9%
period 0.7 < 6.5%
5
0 2 4 6 8 10 12 14 16 18 20 22 24

Diabetes
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  #   
#     6  # 
  
 0  
-
‘•–ƒ– Ž‘™—’•
:
 !
#    
 #
    
   
  
  %
     - /   % 
 
        
 

%
   6  
 % 
   
 
 
6  
    

 -
7 
   
      0  
# 
   
   #     
 
        #
   %
- * 
       


 %   
#    
 
 
  
  - $
   
!'&9:

5HI &$( S   


—’• 94.
 
     
# 
    
  
  
#    
    

#   -
‡…‹’”‘…ƒ–‹‰‹•–‘—’•
/     
   
     
  
# 
#- /  
4  0!
  
 
!# %% 6 %%- /      ,  

  
     
       
 
  0  
   
6
  
 
  -
Check valve ‹‰—”‡͚Ǥ͝ǣ…Š‡ƒ–‹…‘ˆ–Š‡”‡…‹’”‘…ƒ–‹‰
assy •‹‰Ž‡’‹•–‘’—’Ǥ
Cam ‹•’—•Š‹‰ƒ•ƒ’’Š‹”‡’‹•–‘„ƒ…ƒ†
ˆ‘”…‡ǤŠ‡–Š‡’‹•–‘‹•‘˜‹‰„ƒ…Ǧ
™ƒ”†•‹–•—…•–Š‡‡Ž—‡––Š”‘—‰Š–Š‡
‹Ž‡–…Š‡…˜ƒŽ˜‡ȋ‘–Š‡„‘––‘ȌǤŠ‡
•ƒ’’Š‹”‡„ƒŽŽ‹•Ž‹ˆ–‡†ƒ†‘’‡•–Š‡’ƒ–Š
ˆ‘”–Š‡‡Ž—‡–ǤŠ‡–Š‡’‹•–‘‘˜‡•
Saphire ball ˆ‘”™ƒ”†ǡ–Š‡Ž‹“—‹†’—•Š‡•–Š‡‹Ž‡–„ƒŽŽ
†‘™ƒ†…Ž‘•‡•–Š‡’ƒ–Šǡ„—––Š‡‘—–Ž‡–
Piston
„ƒŽŽ‹•Ž‹ˆ–‡†ƒ†‘’‡•–Š‡‘—–Ž‡–˜ƒŽ˜‡
Saphire ring (seat) ȋ—’’‡”ȌǤ

5HI &$( S   


—’• 94.
/   % 
   
    
  
 #   
 !
 
    -
21 D@+  #
  6  - / # 
  
 


    
 -

5HI &$( S   


—’• 94.
͛͘͞’—’•
‹‰—”‡͚Ǥ͞ǣ‹‡™‘ˆƒ‹ˆ‘Ž†ǡ’—’•ƒ††‡‰ƒ••‡”•

Manifold
Buzzer

Reagent A
pump

Reagent
A degazer

Reagent
B pump

Reagent
B degazer ‹‰—”‡͚Ǥ͟ǣš’Ž‘†‡†˜‹‡™‘ˆ’—’

5HI &$( S   


—’• 94.
”‡••—”‡ƒ’‡”•
. 
%
     %   
 ;;
  
  - Coil

 
      % 4 
     % 


# ;;   
 
    
 

 0  
    !
 
    
- 1% 
 %  %
 


   - / 
   %
%     

 
#!

     #      ,
-
(   
6  
 4 
    
  
- / 

   
   
 
  0  #       
%   

# 
     
-
(
 % 

       #    <

OUT
 
  

#!
  
%   
  0! Diaphragm
  #  
4 #   - / 
    
  
  %  
# %
   +-F - /
     #    0   - :
   
    0! IN
   
 

  
  

    

 #   
%
 
  ++ P-
- 1       
21F  
  
-

5HI &$( S   


—’• 94.
Cams Piston Flow/ Pressure ‹‰—”‡͚Ǥ͠ǣ Ž‘™ƒ†’”‡••—”‡
Movement Profiles ’”‘ˆ‹Ž‡•ˆ‘”†‹ˆˆ‡”‡––›’‡•‘ˆ
Profile ’—’•ƒ†…ƒ•Šƒ’‡Ǥ
single piston
Š‡’‹•–‘‘˜‡‡–’”‘ˆ‹Ž‡
™Š‹…Š‹•—•‡†ˆ‘”‡™’—’•
‹••Š‘™ƒ„‘˜‡Ǥ ‹”•–•–ƒ‰‡ȋ͙Ȍ
+ dual piston Šƒ•ƒ•Šƒ”’•Ž‘’‡–‘…‘’‡Ǧ
•ƒ–‡Ž‹“—‹†…‘’”‡••‹„‹Ž‹–›Ǥ
Pressuring Sucking Š‡•‡…‘†•–ƒ‰‡ȋ͚Ȍ‹•–Š‡•‘ŽǦ
single piston (optimized cam) ˜‡–†‡Ž‹˜‡”‹‰•–‡’ƒ†‹–‹•
Delivering –Š‡Žƒ”‰‡•–‹–Š‡’—’‹‰
…›…Ž‡ǡ–Š‡–Š‹”†•–ƒ‰‡ȋ͛Ȍ‹•–Š‡
after dampening (0.5mL dampner) ˆ‹ŽŽ‹‰’”‘…‡†—”‡Ǣ–Š‹••–ƒ‰‡‹•
ƒ„‘—–͙Ȁ͘͝‘ˆ–‘–ƒŽ…›…Ž‡–‹‡Ǥ
Š‹•–›’‡‘ˆ…›…Ž‡‹•…‘–”‘ŽŽ‡†„›ƒ‹…”‘’”‘…‡••‘”ƒ††”‹˜‡„›ƒ•–‡’’‹‰‘–‘”Ǥ—Ž•ƒ–‹‘
’”‘ˆ‹Ž‡’”‘†—…‡†„›–Š‹•’—’‹••Š‘™ƒ„‘˜‡Ǥ•ƒŽŽ˜‘Ž—‡†‹ƒ’Š”ƒ‰†ƒ’‡”…‘„‹‡†
™‹–Š‡Ž‡…–”‘‹…’”‡••—”‡‰ƒ—‰‡‹•‘”‡–Šƒ‡‘—‰Š–‘…‘’‡•ƒ–‡ˆ‘”•Š‘”––‡”’”‡••—”‡
’‡ƒ•Ǥ

5HI &$( S   


—’• 94.
‹‰—”‡͚Ǥ͡ǣƒ’‡”…”‘•••‡…–‹‘
Š‡”‡ƒ”‡–™‘†ƒ’‡”•Ž‘…ƒ–‡†„‡–™‡‡
„‡–™‡‡ ’—’•ƒ†’—”‰‡•Ǥƒ’‡”•Š‘™
‘Ž‡ˆ–ˆ‹‰—”‡‹•‘”‡ƒ‰‡–Ž‹‡Ǥ’”‡••—”‡•‡Ǧ
•‘”‹•‹•–ƒŽŽ‡†‘‘–Š‡”†ƒ’‡”Ǥ

5HI &$( S   


—’• 94.
”‡••—”‡‡ƒ•—”‡‡–
& 

    9: 0     
  

 

   
  

   
 --  
 6- 2 
 <

!    
4  %     
- * 
    !     

    %     %
 #        
 
% - .  

    %  #   !
 
#! 
 !
    

 
    !
%
  
  
         

% 
6 
#! -
 . 21 D@+  
#  
    
6  

   

 
!
    F 
?F    ?+ -
 /


#    6
      - /

     

 
!
 
6-
 &  
   
- D@+ 
@F+ &1.   FE+-

5HI &$( S   


”‘„Ž‡•‹’—’‹‰Ž‹“—‹†• 94.

/ 


  
    
    
%    

!

   
   - :
                

 # 
  #   - / #

 
 
#%     -
‡‰ƒ••‹‰
( %

 #  
   
  4 %  #     
% 
  
   
     


  

  
 4 

 
     6- 1 6     

   #   
 
  
#   6   
 
 #    
    
!

    
   
   
 - /  
 
4

     
%  
 
%    #
.      
  

  

#  

   
 

 1,    0  
%
 :(3/.*" %     
    

 
  6N 

 %!# 6-
 '    0     
 
-
 &   
 
  0   
 
    
 
 -
 <     
   
   0 N      0    

5HI &$( S   


”‘„Ž‡•‹’—’‹‰Ž‹“—‹†• 94.

 

 

-
/   # 
     % 
 
%  
 
 F   #  0  !
      
       
-
‘Ž—–‹‘•—•‡†‹͛͘͞
. 21 D@+ %
  

  - )%          
%
  
 
!
      
 
 %- .   # 
   
   
  

 -

5HI &$( S   


”‘„Ž‡•‹’—’‹‰Ž‹“—‹†• 94.
- 7   

‹‰—”‡͚Ǥ͙͘ǣ‡ƒ‰‡–•’”‹‡
”‹‡‘ˆ”‡ƒ‰‡–•—•‡•˜ƒ…——Ǥƒ…Š”‡ƒ‰‡–’‘”–‹•
Ž‘…ƒ–‡†‹„‘––‘’ƒ”–‘ˆƒ‹ˆ‘Ž†ƒ•ƒ•’‹”ƒ–‹‘–—„‡
‹•‹—’’‡”’ƒ”–Ǥ–Š‡•‹†‡‘ˆƒ‹ˆ‘Ž†ǡ–Š‡”‡‹•ƒ
During „—œœ‡”Ǥ ‹‰Šˆ”‡“—‡…›˜‹„”ƒ–‹‘•‰‡‡”ƒ–‡††—”‹‰
prime, ’”‹‡ƒ‰‰”‡‰ƒ–‡•ƒŽŽ„—„„Ž‡•ǤŠ—•ǡ‡˜‡–—ƒŽ„—„Ǧ
any bubble
remaining in „Ž‡•’”‡•‡–‹”‡ƒ‰‡–Ž‹‡ƒ”‡‡˜ƒ…—ƒ–‡†–Š”‘—‰Š
that place is ˜ƒ…——Ž‹‡Ǥˆ…‘—”•‡”‡ƒ‰‡–ˆ‹––‹‰•„‡’‡”Ǧ
ˆ‡…––‘ƒ˜‘‹†ƒ›‡–”›‘ˆƒ‹”ǤŠ‹•ˆ‹”•–•–‡’‡Ž‹‹ƒ–‡•
aspirated by
vacuum. The
buzzer is used
to «extract»
ƒ›„—„Ž‡…‘‹‰ˆ”‘‘—–•‹†‡ȋ”‡ƒ‰‡–˜‹ƒŽ•ȌǤ
bubbles from
chamber
walls.

Prime
Aspiration

5HI &$( S   


”‘„Ž‡•‹’—’‹‰Ž‹“—‹†• 94.
- 2
7
%     
       !

From manifold

 
     
%  - 2 
Membrane
 #    
     
     -@- 5    
 
   
 
   
%  0    % N  
Vacuum
 % 
  
    
      -
To vacuum

To SSI pump
reservoir

Gases dissolved in reagent


diffuse through membrane

5HI &$( S   


”‘„Ž‡•‹’—’‹‰Ž‹“—‹†• 94.
D- &
/ #
        

%   
%   

- <3/  
            
#   
 
  
% - $
      
#      4  /-

&                 !


 - 5     
#     


 4  

  - 5  

     -
.     #
 #   
 



6-

5HI &$( S   


‹š‹‰ƒ†‹Œ‡…–‹‘ 94.

‹š‹‰
/   (   <      4  /- /  %  
  %  
#  %
4   
#   % 

  4 
  #


 

‹‰—”‡͚Ǥ͙͙ǣ‹”–—ƒŽ˜‹‡™‘ˆ˜‘”–‡šƒ†‡‡•‡…–‹‘˜‹‡™

5HI &$( S   


‹š‹‰ƒ†‹Œ‡…–‹‘ 94.
Œ‡…–‹‘
&

 ,
 
4     
      4 ( P
<      I ?+ - (    %%   

  
   
   #       7
 -
to column to column to column

Lo

Lo

Lo
1 1 1
o

o
2 2 2
p

p
From preparation 6 From pumps From 6 From From 6 From
chamber 3 (Tee) chamber 3 (Tee) chamber 3 (Tee)
5 5 5
4 4 4

① To waste ② To waste
③ To waste

- .     %%  


 
(    

 D     # 

D   ?  
 
#-
- B%   

 
<    

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FP 

     # 


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#-
D- B%   
(- "
#  FP9         
 @ 



 
5HI &$( S   
‹š‹‰ƒ†‹Œ‡…–‹‘ 94.

   


 
   - / 

 
    #     
 

 #  
 #   6
 
 
# ' 
 
-

5HI &$( S   


‘Ž— 94.

‹‡ ‹Ž–‡”•
(     
   #      !
 ,
 
%    
 
   
!
 - &

      %   

 


  P     
   N

#% +-FP 

       #  
 

   + P   - /
   
% 
 
%  %

      
  -
‹‰—”‡͚Ǥ͙͚ǣ‹‡™‘ˆ͛͘͞ˆ”‹–
”‹–Šƒ•–‘„‡…Šƒ‰‡†‡˜‡”›͚͘͝–‡•–•ȋ‘‹•–”—‡–
”‡“—‡•–ȌǤ
 ‹•‘—–‹‰ƒ›„‡Šƒ”†
ȋ‘ǯ”‹‰˜‡”›–‹‰Š–‡ȌǣƒŽ™ƒ›•Šƒ˜‡ƒ
”‡’Žƒ…‡‡–ˆ”‹–Š‘Ž†‡”‹–‘‘Ž„‘šǤ
‘Ž—
- .
!4  


$
 
  
  
   .
!4  

-

5HI &$( S   


‘Ž— 94.
.
!4  

 .:  
 
 
# 

  
   
  
 
 - .

     4- /

4!
  
 &
    Q / 
# 
  6 #      
   -
'  
  6  #%  #    0  
     

%  % -
 :
   4
4   Q / 
  
     
#
     6     
 
 
-
 :

!
 
 

   
.  
4  %
    


        -
(  
 
#   
  
 
   
 
 
 
 - (  '    
  
4  #   
'    
  
4 -
/  

 

  #    

#   
 #   
 
!
 

  

    !4  


!4  



 
   !' 
!4  


 
  
 
   

-

5HI &$( S   


‘Ž— 94.
- <
  


/  

  
  
 

 

   %   


      %  
4- / 


  
4 %
%  !
  

 


 
    B  5 
 
 

  
! 
 
 

  
    
 
- (
    
   
  
     
   
 

 %

 
  
      -
)%     
  21 D@+ 
4  

- )4 
 
 %   
 -

5HI &$( S   


‘Ž— 94.
/ #  

 


  
!
  
   
 - $
 
 
  
     '&9: #  
‹‰—”‡͚Ǥ͙͛ǣ‘Ž—Š‘Ž†‡”˜‹‡™
‘Ž—‹•‡’–ƒ–…‘•–ƒ––‡’‡”ƒ–—”‡ȋ͘͜λγ
͙͘͜λ ȌǤŠ‡ˆ”‘–ƒŽ—‹‹—†‘‘”‹•‘–•Š‘™‘
•…Š‡ƒ–‹…•Ǥ
‹‰—”‡͚Ǥ͙͜ǣ –‡”ƒŽ˜‹‡™‘ˆ…‘Ž—
Column packing
Nut Stainless steel tube

Filters

‘Ž—‹•”‡˜‡”•‡†‡˜‡”›͘͘͝–‡•–•ȋ‘‹•–”—Ǧ
‡–”‡“—‡•–Ȍ

5HI &$( S   


‡–‡…–‘” 94.

/    


 %  
 '&9:- 7 
 0  

 
 


 
-
OD reference ‹‰—”‡͚Ǥ͙͝ǣ‡–‡…–‘”˜‹‡™
OD measure Column ͛͘͞ǡ†‡–‡…–‘”‹•ƒ
Ǽ„Žƒ…„‘šǽ™‹–Š‘’‘••‹Ǧ
Lamp
„Ž‡‹–‡”˜‡–‹‘‹–Š‡ˆ‹‡Ž†
power ȋ‡š…‡’–…‘’Ž‡–‡
supply ‡š…Šƒ‰‡ȌǤŠ‹•‹•ƒ…‘Ž‘Ǧ
”‹‡–‡”™‹–Š‡ƒ•—”‡ƒ–
͙͜͝ƒ†ƒ”‡ˆ‡”‡…‡
To waste Flow cell …Šƒ‡ŽǤƒ’Ž‡’ƒ••‡•
–Š”‘—‰ŠƒˆŽ‘™…‡ŽŽ
†‡•‹‰‡†–‘ƒ˜‘‹†•‹†‡
‡ˆˆ‡…–•ƒ”–‡ˆƒ…–•Ǥ
100 PSI pressure
ƒ’Ž‡‹•†”ƒ‹‡†–‘™ƒ•–‡
regulator –Š”‘—‰Š͙͘͘ ’”‡••—”‡
”‡‰—Žƒ–‘”Ǥ

5HI &$( S   


‹––‹‰•ƒ†–—„‹‰• 94.

5      '&9:        % 


 - (  6   !
    
   

  - .   

 6   %
   #    
   


    6
   
  -
ˆˆ‹––‹‰•Ž‡ƒ
- :6 
6  
     
- 5      /)     !
  


   %  
 
         - .   
    
        %     

      


  
 


   %  
   !     - "
 & 
R !
   #       
%       %
     
 -
- /    
     
- 1       0   #  

   %   - $      
0   

  N 
#%

R   #     



 
      -
D- S
     
    - 6  
          

  #  
   #   

 
 
 - /
%
   


5HI &$( S   


‹––‹‰•ƒ†–—„‹‰• 94.
    
          - <   

    #



         
%  
%  
 -
?- :6  
 

     - (         # 
 
 
 
 

   
      #
   
6- (# 6  4 
       
    


    0 6   %
   
#  -
F- :6   %  
 
 - 1
   6  


    


#        #    %  
- &
  %       
# 
      
- :6   %  
 
 %   

      -
)%   
   - 3     
     
  #  
 
 
    #
   6  #     -

5HI &$( S   


 

/     21 D@+     %  #


  
#    %
    

         
, # !   ,,,   
, 6   ,, 
$ 
," 
   ,," 
!!
, ) %!  
,, )
 $ 
," ) %! !  
, 
! %

5HI &$( S  


‘’‘‡–• 94.

Cleaner pump
Needle assembly High pressure
Dilutor

V7
NO
A

c
NO
O nc
c
no
V6
V8 Pulse dampers

NO
V9
Sample pump
Pump heads
Rheodyne
Sample valve (4ways)
POS: B 6
5

4 1

2
Detector
e
3

Degasserss
D
Heated
ate
t
Column
cuvette
e and frits
V10 Waste
NC
NO
O
NC
NO
reservoir
V3
C V11 C
c nc

c c c
nc nc nc
V12
V V13
V V14
4
Reagent
manifold

Vacuum pump
assembly

C A B D W

5HI &$( S   


Ž—‹†‹…• 94.
Ž—‹†‹…•
Dilutor Cleaner Pump
High Pressure
V4
Prime Valve

V7 Sample
NO valve
Sink Front A

c
NO nc
no
V6
V8
Sink Back
High Pressure
Sample Line Blood Sensor Prime Valve
NO Dampners
Flow Separator
V9
Mixing Motor Peri
V2 Pump Sample
V1 Injection
High Pressure
Valve
pumps
DSJ-0005-001
POS: B 6 041-3866-768
5

4 1
Heated Cuvette Frits
2
T 430 Warming
3 Tube
T 430 Pressure
Sensor
Column
Check Heater
valve Assembly
V10
NC
Vaccum NC
Vacuum
Column Detector
reservoir
NO NO V3
C V11 C Degasers
Pressure c nc

Check Drain
valve
c c c
nc nc nc
V12 V13 V14
100 psi

Manifold Vibrator
V5

Vacuum Pump Assembly Cleaner Reagent Reagent Reagent


Rear Panel Detector Detector Detector Detector

WASTE C A B D W
5HI &$( S   
‹‰Š’”‡••—”‡ˆŽ—‹†‹…• 94.

‹‰—”‡͛Ǥ͙ǣƒ‹ˆ‘Ž†–‘†‡‰ƒ••‡”•ƒ†’—’•

To V6
c (dilutor)
no
o

Reagent A
pump

POS: B 6
5
Reagent A 4 1
degasser 2
3

Reagent B
pump

c c c
Reagent B nc
V12
nc
V13
nc
V14
degasser

C A B D W
5HI &$( S   
‹‰Š’”‡••—”‡ˆŽ—‹†‹…• 94.
‹‰—”‡͛Ǥ͚ǣ ”‘’—’•–‘‹š‡”ƒ†”Š‡‘†›‡
24 cm

V7
NO 16 cm
A

c
53 cm
NO nc
c
no
V6
V8

NO
V9

22 cm

27 cm
POS: B 6
5

4 1

2
From transfer
3
peripump 18.5 cm

To column
V10 prefilter 18 cm
NC NC
NO
O NO V3 21 cm
C V11 C
c nc
To waste
25 cm
c c c
nc nc nc
V12 V13 V14

53 cm

5HI &$( S   


‹‰Š’”‡••—”‡ˆŽ—‹†‹…• 94.
‹‰—”‡͛Ǥ͛ǣ ”‘”Š‡‘†›‡–‘…‘Ž—ƒ††‡–‡…–‘”
V7
NO
A

c
NO nc
c
no
V6
V8

NO
V9

POS: B 6
/


5

 4 1


$

   2

 
3


 

$
 


 

V10  
NC NC 

NO
O NO V3
C V11 C
c nc

& 


5HI &$( S   


ƒ…——ˆŽ—‹†‹…• 94.

‹‰—”‡͛Ǥ͜ǣ
‡‡”ƒŽ˜‹‡™
W\JRQ,':  )7/%  
W\JRQ,'2'  5HJXODWRU36,  
7   &KHFNYDOYH  
7   9  
9  
V7 99  
NO

;/   'HJDVVHU


A
 '6-
c

/  
041-3866-736 V8
O
NO
5HDJHQWPDQLIROG nc
c
no 
V6
'6-
1   9DFXXPUHVHUYRLU  '6-
NO

07//   V9 .1)SXPS 

POS: B 6
001 - 43 cm, 17" 5

from flow separator 4 1

001 - 15 cm, 6"


2
001- 66 cm, 26" to Sampler PCB 001- 10 cm, 4" 001 - 41 cm, 16" 3
Check
T 430 T 430
valve 1/8
001- 41 cm, 16"
001 - 5 cm, 2"

from injector valve n°3


003 - 25.4 cm, 10"
V10 001 - 7.5 cm, 3"
NC NC
from SSI pump degazer
001 - 69cm, 27"
NO NO V3
to red luer (air exaust)
C V11 C
001 - 13 cm, 5"

c nc
001 - 11.5 cm, 4 1/2"
Check valve 1/8 001 - 61 cm, 24"
003 - 10 cm, 4" Regulator from yellow luer
001 - 6.4 cm, 2 1/2" 001 - 11.5 cm, 4 1/2" From detector (cleaner) c c c
001 - 2.5 cm, 1" 100 PSI nc nc nc
T 430 T 220-230
V12 V13 V14
T 430
001 - 20 cm, 8"
to reagent manifold assy
001 - 15 cm, 6"

001 - 2.5 cm, 1"


to waste

C A B D W
5HI &$( S   
ƒ…——ˆŽ—‹†‹…• 94.
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001 - 61 cm, 24"
from yellow luer
(cleaner) 001 - 69cm, 27"
to red luer (air exaust)
001 - 20 cm, 8"
To V7/V8 to assy reagent manifold
Check valve (reagent degazer)
T 430
2x Reagent manifold
MTLL 230
To V9 +
FTLB 230

2 x XL 230
001 - 7.5 cm, 3"
001 - 10 cm, 4" from SSI pump degazer 001 - 6.4 cm, 2 1/2"
T 430
001 - 5 cm, 2"
001 - 15 cm, 6" 001 - 2.5 cm, 1"
001 - 66 cm, 26" T 430
001 - 11.5 cm, 4 1/2"

001 - 43 cm, 17" Check valve 001 - 2.5 cm, 1"


from flow separator to waste
(blood aspiration T 430
and needle cleaning)
001 - 11.5 cm, 4 1/2"

Cleaner peripump

001 - 15 cm, 6" 003 - 10 cm, 4"


N 430-410 From detector
T 220-230
Check valve
003 - 25.4 cm, 10"
001 - 13 cm, 5" from injector valve n°3
001 - 41 cm, 16"
V10 (NO) from V3 (C)
V10 (NC) 001 - 7.5 cm, 3"
001 - 41cm, 16" from SSI pump degazer
T 430 to check valve and vacuum
001 - 2cm, 1" reservoir
V11 (NO)
V 230-220
V11 (NC) MTLP
To pressure sensor
(sampler PCB) L 230

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V12 V13 V14
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2"

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V12 V13 V14
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5HI &$( S   


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5HI &$( S   

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