Académique Documents
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1 -gera:6785/di/ra
ACUPUNCTURE ANAESTHESIA: A REVIEW.
SMALL TJ. american journal of acupuncture.1974,2(3), 147-3.
(eng). rf:33
Vrifiez :
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[AFFECTION SENSITIVE PROPAGEE LE LONG insomnie, langue rouge enduit fin). La douleur musculaire
DES MERIDIENS, RAPPORT CLINIQUE DE 80 CAS]. des extrmits est analyse comme un trouble du Qi et du
LIU CHENG ZHONG. chinese journal of integrated sang dans les mridiens. Le dsquilibre coeur Rein peut
traditional and western medicine. 1984;4(12):711 (chi*). donner des signes proches de l'insuffisance Yin du foie. Le
L'affection est caracterise par des sensations paroxystiques traitement de l'insuffisance du foie du Rein, de la
(paresthsies) progressant le long d'une zone particulire du transformation du Foie Yang du vent et du dsquilibre coeur
corps humain. La crise dbute au niveau d'un point fixe et se Rein : 20VB, 3F, 7C, 3Rn, 6Rt, 20VG, 21VG, 18VB. Le
propage sur une largeur de 10 40 mm. Le trajet correspond traitement ensuite des douleurs musculaires : 4GI, 11GI, 37E,
un mridien. Chaque crise dure 3 5 minutes laissant une 40VB, 41E. Traiter tous les jours 20 minutes. Aprs 5
zone hypoesthsique le long du mridien. Depuis 1959, 224 sances diminution des signes aprs 30 sances tremblements
cas ont t rapports en Chine. Le tableau clinique et douleurs des ? .
correspond celui de la "maladie se dveloppant
automatiquement dans les mridiens" dcrit dans la littrature 26- gera: 30581/di/ra
ancienne, et peut tre appel "pilepsie sensorielle [CLINICAL OBSERVATION ON TCM TREATMENT
propagation mridienne". OF PARKINSON'S DISEASE . ANALYSIS OF 35
CASES]. WANG YONGYAN ET AL. journal of tcm.
18- gera: 8819/di/cg 1986;27(8):22-4 (chi).
RESEARCH ON THE PROPAGATION OF SOUND
INFORMATION ALONG MERIDIANS (PSIM) IN 27- gera: 20781/di/el
PARAPLEGIC PATIENTS. SUN PINGSHENG ET AL. TRAITEMENT D'UN CAS DE PARALYSIE
second national symposium on acupuncture and TREMBLANTE ET PARALYTIQUE. ZHANG JIANQIU
moxibustion,beijing. 1984;:301 (eng). ET AL. in selection des theses de la revue d'acupuncture
de shanghai, shanghai. 1987;:59 (fra).
19- gera: 12638/di/ra Traitement d'un cas de Parkinson voluant depuis 10 ans et
[CAS DE TREMBLEMENTS DES MEMBRES rsistant aux traitements occidentaux ou aux plantes
INFERIEURS]. CHEN KENIAN. shaanxi journal of tcm. chinoises. 20VG, 11GI, 4GI, 3GE, point de paralysie (2cun
1984;5(3):25 (chi). au dessous de 36E, 34VB, 9Rte, 6Rte. 1 sance tous les deux
jours, srie de 10 sances. Aprs 2 sries, amlioration des
20- gera: 12639/di/ra tremblements. A la 3me srie, 20VG est remplac par Si
[CAPITIS TREMOR]. YANG NIEMI. journal of new Shen Cong (1 cm gauche, droite, arrire et avant du 20VG)
chinese medicine. 1984;12:16 (chi). et 20VB et 16VG ajouts. Le patient peut nouveau marcher.
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point prevalence for men and women of 16.9 / 10*5 and 12.4 63- gera: 38774/di/ra
/ 10*5, with the highest prevalence after the fifth decade of MECCANISMO D'AZIONE DELL'AGOPUNTURA
age. The disease was most prevalent in the southern part of NELLA SOPPRESSIONE DELLE CRISI
China, especially in Hunan and Guangxi provinces. The EPILETTICHE. WU DINGZONG. rivista italiana di
incidence was 1.5 / 10*5 / yr in 1986. Both the prevalence medicina tradizionale cinese. 1993;50(2):59-61 (ita).
and incidence of PD in China are lower than those in the
white race and 64- gera: 38870/di/ra
COMBINATION OF ACUPUNCTURE, QIGONG AND
53- gera: 35894/di/ra HERBS IN THE TREATMENT OF PARKINSONISM.
PARKINSON'S DISEASE TREATED WITH WANG XUECHENG. international journal of clinical
TRADITIONAL CHINESE MEDICINE. SAN HONG acupuncture. 1993;4(1):1-7 (eng).
HWANG. international journal of oriental medicine.
1992;17(2):106-7 (eng). 65- gera: 48632/di/ra
[TREATING 11 CASES OF PARKINSONISM WITH
54- gera: 36153/di/ra "DING ZHEN WAN"]. LI HUAI-SHENG. zhejiang
[THE EFFECT OF ELECTROACUPUNCTURE journal of traditional chinese medicine. 1993;28(4):186
THERAPY ON HEART RATE OF PARKINSON (chi).
DISEASE]. X. journal of the japan society of
acupuncture. 1992;42(1):86. (jap). 66- gera: 57195/di/ra
ACUPUNCTURE TREATMENT OF TREMOR IN
55- gera: 36205/di/ra ALCOHOL WITHDRAWAL SYNDROME. MILANOV I
[ORT RESPONSIVE ROUTE TO SUBSTANTIA ET AL. american journal of acupuncture. 1993;21(4):319-
NIGRA AND PARKINSONISM]. X. journal of the japan 22 (eng).
society of acupuncture. 1992;42(1):138. (jap). The aim of this investigation was to establish the efficacy of
acupuncture treatment during the withdrawal period after
56- gera: 39272/di/ra chronic alcohol intake. Twenty five patients who met the
[CLINICAL ANALYSIS ON 50 CASES OF criteria for chronic alcoholism were evaluated by
PARALYSIS AGITANS TREATED WITH TCM electromyography (EMO) for the pattern, frequency and
MAINLY]. LI GENHE. shanghai journal of traditional amplitude of tremor before and after treatment. Patients were
chinese medicine. 1992;2:12 (chi). treated with acupuncture for three weeks and no medication
or alcohol were ingested during this period. After treatment a
57- gera: 42807/di/ra decrease of tremor amplitude and disappearance of tremor in
[TCM CRITERION OF DIAGNOSIS AND some patients were found. However, as revealed by EMG,
THERAPEUTIC EFFECT FOR SENILE TREMOR most patients have a significant reduction of tremor
SYNDROME (FOR TRIAL IMPLEMENTATION)]. amplitude without any change of the tremor frequency. Most
SOCIETY OF GERONTOLOGY CATCM. journal of of the other symptoms of alcoholic withdrawal syndrome
beijing college of traditional chinese medicine. were improved. Spontaneous improvement was ruled out. In
1992;15(4):39 (chi). conclusion acupuncture is effective for treatment of alco-
hohc withdrawal symptoms
58- gera: 42898/di/ra
[A CLINICAL REPORT ON TREATMENT OF 67- gera: 2658/nd/me
CHOREA WITH ACUPUNCTURE : 11 CASES]. XU ETUDE COMPARATIVE DE LA
XIN-HUA ET AL. zhejiang journal of traditional chinese MORPHOTYPOLOGIE DE LA MAIN DE 30 SUJETS
medicine. 1992;27(7):324 (chi). PARKINSONIENS EN MEDECINE
TRADITIONNELLE CHINOISE. LI FOON CHEONG K.
59- gera: 44670/di/ra memoire d'acupuncture, bordeaux ii. 1994;: (fra).
[OBSERVATION ON EFFECTS OF 8 CASES OF Cette tude cas-tmoins propose de comparer la
CEREBELLAR ATAXIA BY SCALP- morphotypologie de la main de 30 parkinsoniens selon les
ACUPUNCTURE]. LI QIAO-JU ET AL. shanxi journal of principes des 5 lments de la Mdecine Traditionnelle
traditional chinese medicine. 1992;8(6):37 (chi). Chinoise. On retrouve chez les parkinsoniens gs avec
hypertonie extrapyramidale une plus grande frquence de
60- gera: 37888/di/ra typologie METAL-BOIS.
[TREATING 11 CASES OF PARKINSONISM WITH
"DING ZHEN WAN"]. LI HUAI-SHENG. zhejiang 68- gera: 3047/di/ra
journal of traditional chinese medicine. 1993;28(4):186 NEUROSTIMULATION IN THE TREATMENT OF
(chi). THE SYMPTOMS OF PARKINSON DISEASE,
PARTICULARY DEPRESSION, PAIN SYMPTOMS,
61- gera: 38193/di/ra HYPOKINESION AND RIGIDITY. THE PL.
[ELECTRICAL ACUPUNCTURE COMBINED WITH acupunctuur. 1994;17(5):15-6 (eng).
POINT INJECTION THERAPY TO TREAT 25 CASES The purpose of this method is to reduce intake of medication
OF BRACHIAL PLEXUS PARALYSIS]. ZENG (anti-Parkinsonian medication). Most Parkinson patients,
ZHAOJIE. hubei journal of traditional medicine. above 60 years, are afflicted with heart disease or
1993;1:37 (chi). cerebrovascular diseases. Due to side effects, anti-
Parkinsonian medication is mostly contra-indicated with
62- gera: 38531/di/ra cardiac diseases. But a new method, namely the
[METHOD OF WARMING KIDNEY AND neurostimulation or electrical stimulation of the central
TONIFYING SPLEEN FOR 20 CASES OF nervous system can reduce the amount of medication to treat
CEREBELLAR ATAXIA]. LI RUKUI. shanghai journal the symptoms of the disease. In the 70s and 80s Douyon and
of traditional chinese medicine. 1993;2:14 (chi). Serby already published in the "Archive of Neurology" about
this method. They noticed that there is an obvious changing
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dopamine had significant positive correlation with the TUINA AND ACUPUNCTURE IN ACCORD WITH AN
numbers of rotation. These findings suggest that point EVOLVING HYPOTHESIS OF ITS CAUSE FROM
injection at experimental Parkinson' s disease had significant THE PERSPECTIVE OF CHINESE TRADITIONAL
correlation with dopamine, and related to serotonin and MEDICINE- PART 2. WALTON-HADLOCK J. american
harmony of neurotransmitters in striatum. journal of acupuncture. 1999;27(1-2):31-49 (eng ).
In Part II of this series, the author continues the discussion of
96- gera: 69108/di/ra a hypothesis based on acupuncture channel theory regarding
[SURVEY OF TREATMENT OF PARKINSON'S the cause of Parkinson's disease (PD). A system of Yin-type
DISEASE WITH ACUPUNCTURE AND Tuina, termed FSR (forceless spontaneous response) evolved
MOXIBUSTION]. HUANG WENYAN ET AL. chinese from this theory; its clinical application has resulted in
acupuncture and moxibustion. 1998;18(4):252 (chi). various degrees of relief from PD symptoms, (e.g., tremor,
rigidity, decreased dyskinesia; improved balance, circulation)
97- gera: 69218/di/ra regardless of the stage of the disease, and in several cases
PRIMARY PARKINSON'S DISEASE: THE USE OF enabled a reduction of conventional medication. This
TUINA AND ACUPUNCTURE IN ACCORD WITH AN installment includes basic instruction in the technique, and a
EVOLVING HYPOTHESIS OF ITS CAUSE FROM discussion of the dyskinesia which occurs during restoration
THE PERSPECTIVE OF TCM. WALTON-HADLOCK J. of Qi to the Large Intestine and Stomach channels during
american journal of acupuncture. 1998;26(2-3):163-177 treatment. A case study chronicles the weekly changes in
(eng). symptoms
The author presents a hypothesis based on acupuncture
channel theory regarding the cause of Parkinson's disease 101- gera: 59881/nd/re
(PD). Following clinical experience with PD patients TRADITIONAL AND COMPLEMENTARY
suggesting a similar history of energetic trauma, a THERAPIES IN PARKINSON'S DISEASE. MANYAM
preliminary observation was conducted to investigate its BV ET AL. adv neurol. 1999;80:565-74 (eng).
prevalence in subjects with PD and in non-PD controls. A Parkinson's disease has existed in different parts of the world
system of Yin-type Tuina, termed FSR (forceless since ancient times. The first clear description is found in the
spontaneous release), was used to locate and assess the ancient Indian medical system of Ayurveda under the name
injury. Results indicated that all observed PD subjects and Kampavata. Traditional therapies in the form of herbal
only one of the control subjects shared such similar injury. preparations containing anticholinergics, levodopa, and
The PD subjects were then treated with a combination of FSR monoamine oxidase inhibitors were used in the treatment of
and acupuncture, resulting in various degrees of relief from PD in India, China, and the Amazon basin. Scientific
their symptoms, (e.g., tremor, rigidity, decreased dyskinesia; reevaluation of these therapies may be valuable, as shown in
improved balance, circulation) regardless of the stage of the the case of Mucuna pruriens and Banisteria caapi.
disease, and in several cases enabled a reduction of Complementary therapies such as massage therapy,
conventional medication. Based on these findings, the author biofeedback, and acupuncture may have beneficial effects for
proposes a hypotheses in which rebellious (retrograde) qi patients and deserve further study.
flow, beginning at the site of injury, could set in motion the
cascade of changes in Qi flow that precipitate the symptoms 102- gera: 59942/di/ra
and neurologic damage found in PD. It is proposed that [CLINICAL AND EXPERIMENTAL STUDIES ON
decreased dopamine is not the cause of PD, but is a side ACUPUNCTURE TREATMENT OF PARKINSONISM].
effect of this cascade of changes. Included REN XIAOQUN ET AL. chinese acupuncture and
moxibustion. 1999;19(10):617 (chi*).
98- gera: 70317/di/ra In the present study, 41 patients of Parkinsonism were
PARKINSONISM. DONGYUN LIANG ET AL. journal treated with acupuncture and 27 case with western medicine
of chinese medicine. 1998;58:21-3 (eng). as control. Results indicated that 9 cases were markedly
effective,24 effective and 8 ineffective,with an effective rate
99- gera: 72915/di/ra of 80.49% in the acupuncture group; One eases was effective,
PROGRESSI NELLA TERAPIA DELLA PARALISI 14 effective and 12 ineffective, with an effective rate of 55 .
AGITANTE MEDIANTE LA MTC. ZHANG YUNLING 56 % in the control group. The therapeutie effect in the
ET AL. rivista italiana di medicina tradizionale cinese. acupuncture group was superior to that in the control group
1998;72(2):81-5 (ita). (P<0.05) . Biochemical study indicated that acupuncture
Clinicamente, la paralisi agitante caratterizzata could raise the content of superoxide dismutase in red blood
principalmente da tremore alle estremit, rigidit muscolare e cells of the patient, and animal experimence showed that
ridotti movimenti muscolari. La malattia esordisce acupuncture increased activities of tyrosine hydroxylase in
lentamente, va gradualmente intesificandosi e generalmente substantia nigra of the midbrain and adrenal medulla in the
si manifesta in et geriatrica o presenile. Essa anche nota rat of
come morbo o sindrome di Parkinson a eziologia ignota,
generalmente trattata con terapia sostitutiva di levodopa che 103- gera: 59957/di/ra
d effetti terapeutici solo a breve termine, ma non in grado ACUPUNCTURE AND HERBS IN THE TREATMENT
di prevenire l'evoluzione naturale della malattia e presenta OF NEURODEGENERATIVE DISORDERS:
importanti effetti collaterali. La ricerca clinica pi recente in ALZHEIMER'S DISEASE, STROKE, AND
MTC ha subordinato la conoscenza delltetiopatogenesi di PARKINSON'S DISEASE. CHEN JK. medical
questa malattia al trattamento differenziato basato sull'analisi acupuncture. 1999;11(1):10-2 (eng ).
dei sintomi e dei segni, ha accresciuto la sua efficacia Neurodegenerative disorders (such as Alzheimer's disease,
terapeutica, ha rallenatto l'evoluzione della malattia e ha sequelae of stroke, and Parkinson's disease) plague a sizable
ridotto notevolmente gli effetti collaterali determinati dai portion of the geriatric population. They are poorly
farmaci di recognized due to low public visibility and social isolation of
those affected. Although neurodegenerative disorders include
100- gera: 59184/di/ra a vast number of illness, this article focuses on Alzheimer's
PRIMARY PARKINSON'S DISEASE: THE USE OF disease, stroke sequelae, and Parkinson's disease.
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lesioned side striatum and prevent D2 receptor up-regulation disturbances in muscular movement according to TCM
in rats with experimental hemiparkinsonism. theory. Of the 10 herbs contained in kami-shoyo-san, we
believe the abovementioned ones are particularly effective in
118- gera: 72578/di/ra helping to reduce the tremor associated with parkinsonism.
[PROBE INTO TREATMENT OF HEREDOATAXIA
WITH SUPPLEMENT QI]. LU MING ET AL. zhejiang 126- gera: 87349/di/ra
journal of tcm. 2000;35(3):107 (chi). [EXPERIENCE ON CLINICAL APPLICATION OF
HEAD ACUPUNCTURE THERAPY]. SU RE LIANG ET
119- gera: 77171/di/ra AL. journal of liaoning college of tcm. 2000;2(2):136
[CLINICAL ANALYSIS OF INTEGRATION OF TCM (chi*).
AND WESTERN MEDICINE ON TREMBLING The head acupuncture treatment has remarkable effect on
PALSY]. LAO GUOPING. hebei journal of tcm. nerve system diseases. The efficiency is 93.3% in 781 cases
2000;22(10):777 (chi*). of sequelae of apoplexy, 77.4% in 53 cases of paralysis
agitans, 89.8% in 98 cases of epilepsy, 92% in 388 cases of
120- gera: 77254/di/ra neurasthenia , 96% in 100 cases of insomnia and 94% in 52
[TREATMENT OF 30 CASES OF PARKINSON'S cases of lumbago and leg aching. It is also effective to such a
DISEASE BY ZHEN CHAN SHU CAPSULE]. FENG difficult and complicated case as diabetes, especially to
GUANGKUI. shaanxi journal of traditional chinese pattern II diabetes. After twenty courses of treatment, the
medicine. 2000;21(11):481 (chi). blood sugar of 156 diabetics have dropped down to normal
level with the efficiency of 90.5%. The head acupuncture is
121- gera: 77268/di/ra based on the theory of Chinese traditional medicine, which is
[REVIEWS AND PROSPECTS ON TCM RESEARCH directed by four methods of examination and eight principal
ON SENILE TREMOR (PARKINSON'S DISEASE)]. Syndromes, is supported by viscera and meridian and
LONG CHENGXIANG. chinese journal of information on combines syndrome-
tcm. 2000;7(10):10 (chi).
127- gera: 87565/di/ra
122- gera: 77649/di/ra [TREATMENT OF PARKINSON'S DISEASE BY
[AN ANALYSIS OF EFFECT OF ACUPUNCTURE IN ACUPUNCTURE COMBINED WITH LASER PRICK
INDUCING BRAINSTERM EVOKED POTENTIAL IN AND ANALYSIS ON DA IN URINE]. ZHANG QIN ET
PATIENTS WITH PARKINSON' S DISEASE]. ZHU AL. chinese journal of information on tcm. 2000;7(12):78
LILI. jiangsu journal of tcm. 2000;21(5):42 (chi). (chi).
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signs with exposure to sunlight, and improvement of clinical dopaminergic neuron degeneration or increase the gene
signs at night. Treatment with antihistamines, nonsteroidal expression of GDNF and BDNF in the dopaminergic
anti-inflammatory drugs, corticosteroids, antimicrobials, fly neurons. The main findings are. (1) Transection of the MFB
control, chiropractic, and acupuncture had limited success. with a wire knife resulted in abnormal ipsilateral rotational
Sixty-one horses had been treated with cyproheptadine; 43 behavior of rats induced by amphetamine and reduction of
had moderate to substantial improvement. CONCLUSIONS DA in the striatum to about 50 % two weeks after the
AND CLINICAL RELEVANCE: Headshaking may have transection. 0 Both chronic low (2 Hz) and high (100 Hz)
many causes. A large subset of horses have similar clinical frequency EA stimulation were effective in attenuating the
signs including shaking the head in a vertical plane, acting as rotational behavior within 2 weeks of MFB transection. The
if an insect were flying up the nostrils, and rubbing the same effect could last for at least 4 weeks in the animals
muzzle on objects. Seasonality and worsening of clinical stimulated with high frequency EA but not low frequency
signs with exposure to light are also common features of this EA. (I The content of DA in the striatum was increased
syndrome. Geldings and Thoroughbreds appear to be significantly in the unlesioned side of both the low and high
overrepresented. Cyproheptadine treatment was beneficial in frequency EA stimulated rats. No increase had been found in
more than two thirds of treated horses. the lesioned side. 9) High frequency EA could increase the
gene expression of GDNF on the unlesioned side of
146- gera: 99777/di/ra substantia nigra reticular (SNr) region, and both sides of the
[EXPERIMENTAL STUDY ON THE PROTECTIVE globus pallidus, while low frequency EA was effective in
EFFECT OF PINGCHAN DECOCTION AND ITS increasing gene expression of GDNF in the unlesioned side
COMPOSITIONS ON FREE RADICAL INJURY IN of globus pallidus. 0 High frequency EA could attenuate the
RAT WITH PARKINSON DISEASE]. LI RU KUI ET AL. degeneration of dopaminergic neurons in the SNC. The low
chinese journal of traditional medical science and frequency EA had no effect. (3) High frequency EA, but not
technology. 2001;8(6):346 (chi*). the low frequency, could increase the gene expression of
BDNF in the SNC and the ventral tegmental area (VTA) of
147- gera: 99960/di/ra the lesioned side of rats after MFB transection, indicating that
[DIAGNOSIS AND TREATMENT OF high frequency EA stimulation could be more effective than
HYPERKINETIC SYNDROME OF CHILDHOOD the low frequency EA in accelerating the synthesis of
WITH TRADITIONAL CHINESE MEDICINE endogenous. neurotrophic factors and in attenuating the
COMBINED WITH WESTERN MEDICINE]. ZHANG degeneration of dopaminergic neurons.
BIAO. jiangsu journal of traditional chinese medicine.
2001;22(12):55 (chi). 152- gera: 112601/di/ra
REFLEXOTHERAPY IN PARKINSONISM.
148- gera: 104412/di/ra WIKTOROWNA ET AL. deutsche zeitschrift fur
[EFFECTS OF ACUPUNCTURE TREATMENT ON akupunktur. 2001;44(2a):262 (deu).
BLOOD LPO AND SOD CONTENTS IN
PARKINSONISM PATIENTS]. DONG XIAOTONG, 153- gera: 115592/di/ra
WANG SHUANGKUN, REN XIAOQUN, ET A. REFLEXOTHERAPY IN PARKINSONISM .
acupuncture research. 2001;26(1):28 (chi*). WIKTOROWNA ET AL. deutsche zeitschrift fur
akupunktur. 2001;44(2a):262 (deu).
149- gera: 104438/di/ra The objective : The analysis of clinical forms of
[TREATMENT OF 86 CASES OF GILLES DE LA parkinsonism . parkinsonism in our region, the efficiency .
TOURETTE'S SYNDROME BASED ON TCM treatment of disease by a method of reflexotherapy in
SYNDROME DIFFERENTIATION]. SUN XIAODENG, combination with hyperbaric oxygenation. Methods:
QIU WENJING. journal of traditional chinese medicine. Revealing of clinical forms of parkinsonism was followed by
2001;42(7):425 (eng). clinico-electrophysiologic characteristics of 262 patients at
the age of from 20 - 85 years. The treatment with
150- gera: 104640/di/ra antiparkinsonic preparations in combination with hyperbaric
[CLINICAL OBSERVATION ON TREATMENT OF oxygenation and acupuncture was carried out under the
MULTIPLE TOURETTE'S SYNDROME WITH SCALP electromyograph control. The main method was scalp therapy
ACUPUNCTURE.]. SHAN YONGHUA, YAO WEIJU. with the effect on the zone of extrapyramidal system and
chinese acupuncture and moxibustion. 2001;21(6):331 frontoparietal triangle in addition to the stimulation on the
(chi*). points of the canal of kidneys. Procedures were carried on
every day. The course of treatment made up 7-10 procedures
151- gera: 111305/di/ra of acupuncture and hyperbaric oxygenation. Results: The
[A MECHANISM STUDY ON THE EFFECT OF distribution of parkinsonism in the Amur Region made up
ELECTROACUPUNCTURE ON A PARTIALLY 43,4: 100000 of the population, in the town 97: 100000. The
LESIONNED RAT MODEL OF PARKINSON'S correlation of the men and women was 1: 1,5. The disease
DISEASE]. LIANG XIBIN, LIU XIANYU, LI FENGQIAO, began more often at he age of 50-59 (34,9 % of the patients)
ET AL. acupuncture research. 2001;26(3):210 (chi*). and 60-69 (30,5 %) years. All patients had the syndrome of
Acupuncture has been applied in the treatment of Parkinson's insufficiency of kidneys. The decrease of hyperkinesis,
Disease (PD) in China for over decades. Clinical practice rigidity after the treatment was confirmed by the decrease of
revealed that it could relieve the sufferings of PD patients and the pear activity on electromyogram in all patients.
improve their life quality. Besides, acupuncture is also Conclusion : Among nosologic forms the Parkinson's disease
effective for other neurological disorders such as optic nerve proceeding as a syndrome of insufficiency of kidneys
atrophy, spinal cord injury and brain dysplasia. But the prevailed. The therapeutic effect was higher in combined
mechanism underlying the phenomenon is still unknown. In treatment with the daily procedures of scalpotherapy. The
the present study, we gave high and low frequency efficiency of this treatment can be controlled with the help of
electroacupuncture (EA) stimulation to the medial forebrain electromyography.
bundle (MFB) transected rats in order to find whether EA
could attenuate the abnormal rotational behavior and 154- gera: 152110/di/el
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effective rate was 74. 19%. The improvements of the 169- gera: 111722/di/ra
symptoms were as follows: To tremor, the effective rate was [TREATMENT OF 36 CASES OF PARKINSONIAN
86. 67% to rigidity of limbs was 70. OO%, to constipation SYNDROME WITH TCM COMBINED WITH
was 7 2. 7 2 % and to insomnia was 2 8. 5 7 % The Webster WESTERN MEDICINE]. LI XIAN. jiangsu journal of
points decreased averagely 6. 4 7 after the treatment, the tcm. 2003;24(1):14 (chi).
difference was significant (P<O. 01). This had suggested that
ZD had good effect on Parkinson's disease. 170- gera: 112389/di/ra
EFFETTO DELL'AGOPUNTURA SUL POTENZIALE
162- gera: 106570/di/ra EVOCATO UDITIVO DEL TRONCO CEREBRALE
[CLINICAL OBSERVATION ON TREATMENT OF 30 NEL MORBO DI PARKINSON. WANG LINGLING ED
CASES OF PARKINSONIAN SYNDROME WITH ALTRI. rivista italiana di medicina tradizionale cinese.
WESTERN MEDICINES COMBINED WITH 2003;91(1):33 (ita*).
DINGCHAN LIQUID]. GU XI-ZHEN. journal of nanjing
university of traditional chinese medicine. 2002;18(5):275 171- gera: 113121/di/ra
(chi). [ETIOPATHOLOGY AND TREATMENT BASED ON
SYNDROME DIFFERENTIATION OF
163- gera: 107667/di/ra EPILEPTICISM]. HUANG PEIXIN, ET AL. chinese
[EFFECT OF XIFENG JINGNING DECOCTION ON archives of tcm. 2003;21(2):176 (chi).
THE LEVELS OF PLASMA DOPAMINE AND AMINO
ACID IN THE CHILDREN WITH GILLES DE LA 172- gera: 113918/di/ra
TOURETTE SYNDROME]. LIU CHUSHENG ET AL. [CLINICAL STUDY ON HEAD POINT-THROUGH-
chinese journal of information on traditional chinese POINT ELECTROACUPUNCTURE FOR
medicine. 2002;9(5):19 (chi*). TREATMENT OF PARKINSON'S DISEASE]. WANG
SHUN, ZHOU ZHENKUN, HU BINGCHENG, ET AL.
164- gera: 107723/di/ra chinese acupuncture and moxibustion. 2003;23(3):129
[CONTRAST CLINICAL OBSERVATION IN THE (chi*).
TREATMENT OF PARKINSON'S DISEASE WITH
YICHAN DECOCTION]. YANG MING HUI, DOU 173- gera: 114713/di/ra
YONG-QI, LIU YI, ET AL. chinese journal of integrated [TREATMENT OF 36 CASES OF PARKINSONIAN
traditional and western medicine in intensive and criti. SYNDROME WITH TCM COMBINED WITH
2002;9(5):256 (chi*). WESTERN MEDICINE]. LI XIAN. jiangsu journal of
tcm. 2003;24(1):14 (chi).
165- gera: 108087/di/ra
[DISCUSSION ON PATHOGENESIS OF 174- gera: 115380/di/ra
PARKINSON'S DISEASE TREATED WITH EFFETTO DELL'AGOPUNTURA SUL POTENZIALE
METHODS OF TONIFYING THE KIDNEY AND EVOCATO UDITIVO DEL TRONCO CEREBRALE
REMOVING TOXIC SUBSTANCES]. WANG JIE-MIN, NEL MORBO DI PARKINSON. WANG LINGLING ED
WANG YA-LI. shandong journal of tcm. 2002;21(10):581 ALTRI. rivista italiana di medicina tradizionale cinese.
(chi). 2003;91(1):33 (ita*).
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acupuncture and tuina science. 2005;3(4):52 (eng). authors of this article as the result of a Qi deficiency in the
spleen functional system (depletio of o. lienalis, pixu). This
240- gera: 142604/di/ra deficiency has an influ-ence on both the kidney functional
[INFLUENCE OF ELECTROACUPUNCTURE ON system (o. renais, shen) and the liver functional system (o.
THE APOPTOSIS OF SUBSTANTIA NIGRA hepaticus, gan) which, in turn, causes blockages of phlegm
DOPARNINERGIC NEURONS IN A RAT MODEL OF (pituita, tan) and Xue stases. The article describes the precise
PARKINSON' S DISEASE]. MA J, ZHU SX, WANG mecha-nisms of the disease, explains how the typicaL
YC;AL. shanghai journal of acupuncture and symptoms arise and provides the reasons for the increased
moxibustion. 2005;24(10):36 (chi*). incidence of Parkinson's disease. The authors recommend
Objective To investigate the influence of electroacupuncture that ther-apy should first of all concentrate on strengthening
on the apoptosis of substantia nigra dopaminergic neurons in the spleen functional system (o. lienalis, pi), transforming the
parkinsonism rats. Methods A rat model of unilateral phlegm (pituita, tan), clearing the reticular channels
suBstantia nigra-destroyed Parkinson's disease was made by (reticulares, luo) and removing wind (ventus, feng). Tak-ing
injecting 6-OHDA into the right mesencephalic substantia a case study as an example, the authors demonstrate their
nigra. The rat model was treated with electroacupuncture. approach and indicate the prescription they use. By adopting
The number of substantia nigra apop-totic dopaminergic the approach described, they were able to
neurons was determined By a TH and TUNEL double
labeling method in the normal, sham operation, model and 243- gera: 143058/di/ra
electroacupuncture groups. Results The number of apoptotic L'ESPERIENZA DEL DR. SHI YANQING NEL
dopaminergic neurons was significantly larger on the TRATTAMENTO MEDIANTE AGOPUNTURA
destroyed sicle in parkinsonism rats than in the normal group DELLA PARALISI AGITANS. SHI XIAOWEN. rivista
(P < 0.01) and on the undestroyed side (P < 0.01). italiana di medicina tradizionale cinese. 2005;101(3):43
Electroacupuncture could effectively decrease the number of (ita).
apoptotic dopaminergic neurons in parkinsonism rats (P < 0. Dr. Shi Yanqing, a chief physician of traditional chinese
05). Conclusion The apoptosis of dopaminergic neurons may medicine, is an expert using warm-needling therapy to treat
be involved in the occurrence of Parkinson's disease. obstinate and miscellaneous diseases. In his long years of
clinical practice, Dr. Shi has treated several tens of paralysis
241- gera: 142981/di/ra agitans cases, and obtained quite good therapeutic effects as
[A CASE OF ACUPUNCTURE TREATMENT FOR is introduced in the following.
INDEFINITE COMPLAINTS ACCOMPANYING
WALLENBERG SYNDROME]. KINUTA AKIRA. 244- gera: 143138/di/ra
journal of the japan society of acupuncture and ATTUALE SITUAZIONE E PROSPETTIVE DEL
moxibustion. 2005;55(4):73 (chi). TRATTAMENTO SECONDO LA MTC DELLA
[Objective] For objective investigation of symptomatic MALATTIA DI PARKINSON. HE LINCHENG. rivista
changes in indefinite complaints accompanying Wallenberg italiana di medicina tradizionale cinese. 2005;102(4):74
syndrome, efficacy of acupuncture treatrnent was (ita).
investigated following seven acupuncture treat-ments using Parkinson's disease (PD) is a chronic degenerative disease of
charts on indefinite complaints developed by Yasuzo Kurono, the nervous system marked by tremor, muscle rigidity,
the chief of the hidefmite Com-plaint Section in the Japan hypokinesis , abnormal posture, and pathologically, selective
Society of Acupuncture and Moxibustion, Research loss of dopaminergic neurons in the substantia nigra of the
Conunittee. [Design] A case report providing descriptive midbrain and obvious decrease of dopamine content in the
research [Methods] Single acupuncture was administered by striatum. It is encountered mostly in the middle- aged and old
zuishou therapy (therapy based on the symptoms), taikyoku persons and is one of main causes inducing their deformity.
therapy (basic meridian points for total body adjustment The morbidity of this disease tends to increase with gradual
according to the Kurono style) and topical therapy, using 30- aging of the population. In recent years, TCM treatment of
mm 16-guage needles. The charts on indefinite complaints this disease has obtained gratifying achievements. A review
were used for assessment, and the treat-ment period was 52- follows.
days, from May 20 to July 10, 2003 (seven times). [Results]
Improvement of the indefinite complaints was observed, and 245- gera: 144109/di/ra
effect assessment using the charts on indefinite complaints CLINICAL ANALYSIS ON TREATMENT OF
showed marked improvement. Improvement of symptoms PARKINSON'S DISEASE BY ACUPUNCTURE OF
associating Wallenberg syn-drome was also observed. THE MAIN POINTS ON THE GOVERNOR VESSEL
[Conclusions] Efficacy of acupuncture treatment for the MERIDIAN. LI XIAOJUN. european journal of
indefinite complaints accompanying Wallenberg syn-drome integrated eastern and western medicine. 2005;13(3):23
was suggested by the improvement of symptoms associated (eng).
with Wallenberg syndrome. The patient subsequently Parkinson's disease, also called shaking palsy, is a
retumed to work, indicated the potential of acupuncture commonly seen degenerative disease of the nervous system
treatment as QOL. in e middle-aged and elderly, clinically characterized mainly
by static tremor, bradykinesia and an increase of uscular
242- gera: 143004/di/ra tension. At present, there is no therapy or radical cure for it.
[THE SIGNIFICANCE OF THE SPLEEN The author treated 30 cases of Parkinson's sease by western
FUNCTIONAL SYSTEM (O. LIENALIS, PI) IN THE medicine combined with acupuncture at points on the
TREATMENT OF PARKINSON'S DISEASE]. MA Governor Vessel Meridian and control vestigation was
YUNJI,WU JITAO. chinesische medizin. 2005;20(3):117 conducted with satisfactory results as reported in the
(deu). following.
In this article the authors present their views on the ever
increasing incidence of Parkinson's disease, which is assigned 246- gera: 144882/ra/di
to the category in Chinese medicine described as "shaking THE SIGNIFICANCE OF THE SPLEEN
and trembling" (chanzhen). In con-trast to the way it is FUNCTIONAL SYSTEM (O. LIENALIS, PI) IN THE
presented in classical works, the disease is described by the TREATMENT OF PARKINSON'S DISEASE. MA
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substantia nigra and thestriatum of the destroyed side inhibit the down-regulation of expression of BDNF and
increased significantly (P < 0.01), and the number of nerve BDNF mRNA of SNC in PD mice which maybe con-tribute
stem cells and the number of transformed neurons in the to its effect in raising the synaptic plasticity of the
destroyed side of the substantia nigra and the striatum degenerative dopaminergic neurons.
increased significantly only in the Shuanggu Yitong group (P
< 0.01). CONCLUSION: Shuanggu Yitong needling method 255- gera: 141763/di/ra
can induce proliferation and differentiation of nerve stem [EFFECTS OF ELECTROACUPUNCTURE ON
cells in the substantia nigra and the striatum regions in the BEHAVIORS AND DOPAMINERGIC NEURONS IN
Parkinson's disease model rat. THE RAT OF PARKINSON'S DISEASE]. MA J, WANG
YC, GAN SY. chinese acupuncture and moxibustion.
252- gera: 125821/di/ra 2006;26(9):655 (chi*).
[EFFECTS OF HEAD POINT-THROUGH-POINT OBJECTIVE: to explore the possibility of
ELECTROACUPUNCTURE ON SOD AND LPO IN electroacupuncture (ea) for prevention of the injury of
THE PATIENT OF PARKINSON'S DISEASE]. WANG dopaminergic neurons in the substantia nigra of the rat with
S, CAI YY, SHANG YJ, JIN-RONG L. chinese parkinson's disease. methods: wistar rats were randomly
acupuncture and moxibustion. 2006;26(4):240-2. (chi). divided into a normal group, a model group, a sham-
OBJECTIVE: To observe clinical therapeutic effect of head operation group and an ea group. 6-oh-da was injected into
point-through-point electroacupuncture on Parkinson's right substantia nigra of the midbrain to made parkinson's
disease and the mechanism. METHODS: Seventy-six cases disease rat model with single side substantia nigra injury, and
of Parkinson's disease were randomly divided into a th/tunel method and rotation behavior observation method
treatment group (n=37) treated with head point-through-point were used to observe changes of rotation behavior and
electroacupuncture and oral administration of madopa, and a apoptosis of dopaminergic neurons in the substantia nigra
control group (n=39) with only oral administration of after ea at "taichong" (lr 3) and "fengfu" (gv 16) for 3 d, 7 d
madopa. Superoxide dismutase (SOD) and lipids peroxides and 14 d. results: the rotation times/min were same at 3 d, 7 d
(LPO) were determined before and after treatment. and 14 d were the basically same in the model group, and at
RESULTS: The effective rate was 97.3% in the treatment 14 d significantly decreased in the ea group (p<0.05); the
group and 61.5% in the control group with a very significant rotation starting time at 7 d and 14 d in the model group were
difference between the two groups (P < 0.01). SOD activity significantly longer than those in the ea group (p<0.05); the
and LPO content were significantly improved after treatment rotation lasting time at 3 d, 7 d and 14 d in the model group
in the treatment group (P < 0.01), with a significant and the ea group were gradually shortened (p<0.01, or
difference between the two groups (P < 0.01). p<0.05), but at 7 d, 14 d in the model group were
CONCLUSION: Head point-through-point significantly longer than those in the ea group (p<0.05); the
electroacupuncture can improve SOD activity and LPO da neuron apoptosis number in the model group were
content in the body so as to cure Parkinson's disease. significantly higher than those in the normal group, with a
very significant difference (p<0.01); the apoptosis number in
253- gera: 141270/nd/re the ea group tended to decrease, at 7 d and 14 d were
EARLY DESCRIPTIONS OF PARKINSON DISEASE significantly lower than that in the model group (p<0.05).
IN ANCIENT CHINA. ZHANG ZX, DONG ZH, ROMAN conclusion: electroacupuncture can effectively prevent from
GC. arch neurol. 2006;63(5):782-4 (eng). injury of dopaminergic neurons in the substantia nigra of the
rat with parkinson's disease.
254- gera: 141686/di/ra
[EFFECT OF ELECTROACUPUNCTURE ON THE 256- gera: 141844/di/ra
EXPRESSION OF BDNF AND BDNF MRNA IN [OBSERVATIONS ON THE EFFICACY OF
PARKINSON'S DISEASE MICE]. TANG YONG, YU ACUPUNCTURE PLUS WESTERN DRUG ON
SHU-GUANG, CHEN JIN. acupuncture research. REHABILITATION TREATMENT OF PARKINSON' S
2006;31(1):38 (chi*). DISEASE]. YANG DAN-HONG, CHEN HUA DE,
Objective: To observe the effect of electroacupuncture (EA) FANG ZHEN. journal of clinical acupuncture and
on the expression of brain-derived neurotrophic factor moxibustion. 2006;22(6):16 (chi*).
(BDNF) in substantia nigra compacta (SNC) of Parkinson's Objective: To observe the therapeutic effect of Acupuncture
disease (PD) mice so as to study the synaptic plasticity. plus western, medicine on rehabilitation treatment of
Methods: Twenty-four male mice (C57BL/6J) were Parkinson' s Dis-ease(PD) .Method 26 patients with PD(in
averagely and randomly divided into normal control, EA, Hoehn - Yahr IV phase) were selected and randomly equally
model and model +EA groups. PD model was induced by divided into the Acupuncture plus Medopa treatment group
injection ( i. p. ) of 1-methy1,4-phenyl- 1, 2, 3, 6 and the Medopa therapy group as a control, to-tally for 4
tetrahydropyridine (30 mg/kg). EA (2-100 Hz, 2-4 V, dense- courses. To observe the score d UPDRS and the symptoms.
sparse waves) was applied to "Hegu" (LI 4) and "Taichong" Results The tatally effective rate, in the treated group and the
(LR 3) for 20 min, once daily. After 21 treatments, the mice control group was 84.6% and 61.5% . The former is
were killed for sampling SNC tissue which was then cut into obviously better than, the latter( P < 0.05) . UPDRS scoring
sections for detecting the expression of BDNF and BDNF in the treated group lowered after 4 courses treatment as
mRNA by immunohistochemical and in situ hybridization compared with that before treatment ( P < 0.05, P < 0 01) .
techniques respectively. Results: Both immunohistochemical UPDRS scoring d the control group was a lifter lower with
and in situ hybridization assays showed that compared with no significance. The improvement of symptoms in the treated
normal control group, the number of BDNF and BDNF group was bet-ter than that in the control group ( P < 0. 05, P
mRNA positive cells and integral optical density (OD) values < 0.01) . Conclusion Acupuncture plus western mediaine can
of model group were significantly lower ( P< 0.05, 0.01); effectively the clinic symptoms of Parkinson' s Disease and
compared with model group, the number of BDNF and the
BDNF mRNA positive cells and integral OD values in model
+EA group were significantly higher (P<0.05, 0.01). No 257- gera: 141961/di/ra
significant differences were found among normal control, EA FURTHER DISCUSSION ON THE THREE METHODS
and model + EA groups in these indexes. Conclusion: EA can FOR STAGE-TREATMENT OF PARKINSON'S
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21
DISEASE. ZHAO GUOHUA TREATING. eastwest Objective To explore the possibility of electroacupuncture
integration medicine. 2006;4(2):36 (eng). (EA) for prevention of the injury of do-paminergic neurons in
Based on repeated clinical prac tice and scientific research the substantia nigra of the rat with Parkinson's disease.
on the thre methods for stage-treatment of Parlcin son's Methods Wistar rats were randomly divided into a normal
disease put forward in early year: this essay further discusses group, a model group, a sham-operation group and an EA
the division of the three stages of Parkinson's disease. Early group. 6-OH-DA was injected into right substantia nigra of
stage people having already had the manifestations of Par the midbrain to made Parkinson's disease rat model with
kinson's disease, but with shorter duration and milde single side substantia nigra injury, and TH/TUNEL method
symptoms, which do not affect their daily life and work and and rotation behavior observation method were used to
having their modified Hoehn & Yahr grading fron grade 1.0 observe changes of rotation beha-vior and apoptosis of
1.5. Mid stage: people having the symptom and signs of dopaminergic neurons in the substantia nigra after EA at
Parkinson's disease getting worse and af fecting their daily "Taichong" (LR 3) and "Fengfu" (GV 16) for 3 d, 7 d and 14
life and work, necessary for treat ment; and having their d. Results The rotation times/min were same at 3 d, 7 d and
modified Hoehn & Yahr gradin from grade 2 3. Late 14 d were the basically same in the model group, and at 14 d
stage: people having severe clini cal symptoms of Parkinson's significantly decreased in the EA group (P<O. 05); the
disease, with the therapeu tic effect of Levodopa preparation rotation starting time at 7 d and 14 d in the model group were
insufficient for then to maintain their daily life; and having significantly longer than those in the EA group (P<0. 05) ;
their modifie( Hoehn & Yahr grading from grade 4 5. The the rotation lasting time at 3 d, 7 d and 14 d in the model
three trea ting methods are: Chinese medical treatment group and the EA group were gradually shortened (P<0. 01 ,
adopte( at the early stage; combined treatment with Chinese or P< 0. 05) , but at 7 d, 14 d in the model group were
and Western medicine at mid stage; and significantly longer than those in the EA group (P<0. 05); the
DA neuron apoptosis number in the model group were
258- gera: 142266/di/ra significantly higher than those in the normal group, with a
CLINICAL OBSERVATION ON ACUPUNCTURE very significant difference (P<0. 01); the apoptosis number.
TREATMENT OF PARKINSON'S SYNDROME. ZOU in the EA group tended to decrease, at 7 d and 14 d were
YONG. journal of acupuncture and tuina science. significantly lower than that in the model group (P<0. 05).
2006;4(4):211 (eng). Conclusion Electroacupuncture can effectively prevent from
Objective: To explore if the therapeutic effect can be injury of dopaminergic neurons in the substantia nigra of the
enhanced, the dose of levodopa-like medications can be rat with Parkinson's disease.
decreased and the complications can be reduced by
acupuncture treatment in the patients with Parkinson's disease 261- gera: 143355/di/ra
(PD) who took levodopa-like medications for a long time. [EFFECT OF ELECTROACUPUNCTURE ON THE
Methods: thirty cases of the patients, most of whom were EXPRESSION OF BDNF AND BDNF MRNA IN
noticed with the decreased therapeutic effect and drag- PARKINSON'S DISEASE MICE]. TANG YONG, YU
induced complications, were treated by puncturing Shuigou SHU-GUANG, CHEN JIN. acupuncture research.
(GV 26) and Baihui (GV 20), by reduction of Madopa dose, 2006;31(1):38 (chi).
and the patients' conditions and complications were evaluated Objective: To observe the effect of electroacupuncture (EA)
six months later. Results: After treatments for six months, the on the expression of brain-derived neurotrophic factor
physiological functions were improved and the dose of (BDNF) in substantia nigra compacta (SNC) of Parkinson's
Madopa was reduced and the total effective rate was 66.7%. disease (PD) mice so as to study the synaptic plasticity.
Conclusion: After acupuncture treatments in PD patients, the Methods: Twenty-four male mice (C57BL/6J) were
therapeutic effects of levodopa were enhanced, with its dose averagely and randomly divided into normal control, EA,
and model and model +EA groups. PD model was induced by
injection (i. p. ) of 1-methyl, 4-phenyl- 1, 2, 3, 6
259- gera: 142649/di/ra tetrahydropyridine (30 mg/kg). EA (2-100 Hz, 2-4 V, dense-
[CLINICAL OBSERVATIONS ON ACUPUNCTURE sparse waves) was applied to "Hegu" (LI 4) and "Taichong"
TREATMENT OF PARKINSON' S DISEASE]. ZHOU Y. (LR 3) for 20 min, once daily. After 21 treatments, the mice
shanghai journal of acupuncture and moxibustion. were killed for sampling SNC tissue which was then cut into
2006;25(1):27 (chi*). sections for detecting the expression of BDNF and BDNF
Objective To investigate if acupuncture treatment can mRNA by immunohistochemical and in situ hybridization
improve the curative effect, decrease the dosage of L-Dopa techniques respectively. Results: Both immunohistochemical
and reduce the complications in Parkinson's disease (PD) and in situ hybridization assays showed that compared with
patients who have taken L-Dopa-kind medicine-fora long normal control group, the number of BDNF and BDNF
time. Methods Thir-ty PD patients, in most of whom there mRNA positive cells and integral optical density (OD) values
were the reduced effect and drug complications, were of model group were significantly lower ( P< 0.05, 0.01);
selected and treated by acupuncture of points Shuigou , compared with model group, the number of BDNF and
Baihui , etc with the dosage of medopa decreased. The BDNF mRNA positive cells and integral OD values in model
patients' conditions and the complications were evaluated 6 +EA group were significantly higher (P<0.05, 0.01). No
months later. Results After 6 months'treatment , the function significant differences were found among normal control, EA
improved in degree and the dosage of medopa decreased, and model + EA groups in these indexes. Conclusion: EA can
with a total efficacy rate of 66.7% . Conclusion Acupuncture inhibit the down-regulation of expression of BDNF and
treatment can improve aie curative effect of L-Dopa-kind BDNF mRNA of SNC in PD mice which, maybe con-tribute
medicine, decrease the dosage of the to its effect in raising the synaptic plasticity of the
degenerative dopaminergic neurons.
260- gera: 143230/di/ra
[EFFECTS OF ELECTROACUPUNCTURE ON 262- gera: 143427/di/ra
BEHAVIORS AND DOPAMINERGIC NEURONS IN CLINICAL OBSERVATION ON ACUPUNCTURE
THE RAT OF PARKINSON'S DISEASE]. MAJUN, TREATMENT OF PARKINSON'S SYNDROME. ZOU
WANG YAN-CHUN, GAN SHUI-YONG. chinese YONG. journal of acupuncture and tuina science.
acupuncture and moxibustion. 2006;26(9):655 (chi). 2006;4(4):211 (eng).
gera 2011
22
Objective: To explore if the therapeutic effect can be sparse waves) was applied to "Hegu" (LI 4) and "Taichong"
enhanced, the dose of levodopa-like medications can be (LR 3) for 20 min, once daily. After 21 treatments, the mice
decreased and the complications can be reduced by were killed for sampling SNC tissue which was then cut into
acupuncture treatment in the patients with Parkinson's disease sections for detecting the expression of BDNF and BDNF
(PD) who took levodopa-like medications for a long time. mRNA by immunohistochemical and in situ hybridization
Methods: thirty cases of the patients, most of whom were techniques respectively. Results: Both immunohistochemical
noticed with the decreased therapeutic effect and drug- and in situ hybridization assays showed that compared with
induced complications, were treated by puncturing Shuigou normal control group, the number of BDNF and BDNF
(GV 26) and Baihui (GV 20), by reduction of Madopa dose, mRNA positive cells and integral optical density (OD) values
and the patients' conditions and complications were evaluated of model group were significantly lower ( P< 0.05, 0.01);
six months later. Results: After treatments for six months, the compared with model group, the number of BDNF and
physiological functions were improved and the dose of BDNF mRNA positive cells and integral OD values in model
Madopa was reduced and the total effective rate was 66.7%. +EA group were significantly higher (P<0.05, 0.01). No
Conclusion: After acupuncture treatments in PD patients, the significant differences were found among normal control, EA
therapeutic effects of levodopa were enhanced, with its dose and model + EA groups in these indexes.Conclusion: EA can
and inhibit the down-regulation of expression of BDNF and
BDNF mRNA of SNC in PD mice which, maybe con-tribute
263- gera: 143538/di/ra to its effect in raising the synaptic plasticity of the
OPEN-LABEL TRIAL REGARDING THE USE OF degenerative dopaminergic neurons.
ACUPUNCTURE AND YIN TUI NA IN PARKINSON'S
DISEASE OUTPATIENTS: A PILOT STUDY ON 265- gera: 143858/nd/re
EFFICACY, TOLERABILITY, AND QUALITY OF TRADITIONAL CHINESE MEDICINE FOR
LIFE. ENG ML, LYONS KE, GREENE MS, PAHWA R. PARKINSON'S DISEASE: A REVIEW OF CHINESE
journal of alternative and complementary medicine. LITERATURE. LI Q, ZHAO D, BEZARD E. behav
2006;12(4):395-9. (eng). pharmacol. 2006;17(5-6):403-10 (eng).
OBJECTIVES: This study evaluates the effects of sequential Occidental medicine has a given definition for Parkinson's
tui na massage, acupuncture, and instrument- delivered disease and knowledge of Parkinson's disease
qigong for patients with Parkinson disease (PD) over a 6- pathophysiology has led to development of its therapeutic
month period. DESIGN: Patients received weekly treatments, management. Parkinson's disease, however, is likely to have
which included tui na massage prior to acupuncture followed always existed in different parts of the world. Description and
by instrument-delivered qigong. Each patient was assessed at management of this neurodegenerative condition could be
baseline and at 6 months. SETTING: The setting was an found in ancient medical systems. Here, we introduce the
outpatient research/academic clinic for patients with PD and philosophical concepts of traditional Chinese medicine and
nonacademic acupuncture clinic. SUBJECTS: Twenty-five the description, classification and understanding of
(25) patients with idiopathic PD were the subjects. parkinsonian symptoms in traditional Chinese medicine. We
OUTCOME MEASURES: Before and after treatment have conducted an in-depth review of Chinese literature
patients were evaluated with the Unified Parkinson Disease reporting anti-parkinsonian and anti-dyskinetic efficacy of
Rating Scale (UPDRS), Hoehn and Yahr Staging (H&Y), more than 60 traditional medicines in Parkinson's disease
Schwab and England Activities of Daily Living (S & E), patients. A number of issues, however, plague the relevance
Beck Depression Inventory (BDI), Parkinson's Disease of these reports and call for a scientific re-evaluation of these
Questionnaire (PDQ-39) quality of life assessment, and therapies in preclinical models of Parkinson's disease before
patient global assessments. RESULTS: There were no proposing traditional Chinese medicine-based symptomatic
significant improvements in treatment measures; however,
there was a 2.4-point worsening in UPDRS motor scores 266- gera: 144355//ra
(24.0 versus 26.4, p = 0.018). There was a 16% improvement IS IT FEASIBLE TO RUN A SUBJECT- AND
in the PDQ- 39 total score (23.2 versus 19.6, p = 0.044) and a ASSESSOR-BLIND RCT TO EVALUATE THE
29% improvement in the BDI (9.6 versus 6.8, p = 0.006). EFFECT OF INTRAMUSCULAR ACUPUNCTURE
Sixteen (16) patients reported moderate to marked FOR PARKINSONS DISEASE?. Park J. focus on
improvement. There were no adverse effects. alternative and complementary therapies. 2006;11(1):40
CONCLUSIONS: Acupuncture is safe and well tolerated in (eng).
patients with PD. Most patients reported subjective rsum et commentaire de : Cristian A, Katz M, Cutrone E,
improvement. The BDI and PDQ-39 total score, measuring Walker RH. Evaluation of acupuncture in the treatment of
depression and quality of life, demonstrated some Parkinsons disease: a double-blind pilot study. Mov Disord
improvement, but UPDRS motor scores worsened. 2005; 20:
gera 2011
23
observation method were used to observe changes of rotation exploring acupuncture mechanisms in treatment of cerebral
behavior and apoptosis of dopaminergic neurons in the infarction, and further shows the specificity of acupoints-
substantia nigra after EA at "Taichong" (LR 3) and "Fengfu" brain functional region.
(GV 16) for 3 d, 7 d and 14 d. RESULTS: The rotation
times/min were same at 3 d, 7 d and 14 d were the basically 270- gera: 145403/di/ra
same in the model group, and at 14 d significantly decreased CROSS-CULTURAL EVALUATION OF THE SHORT
in the EA group (P<0.05); the rotation starting time at 7 d and FORM 8-ITEM PARKINSON'S DISEASE
14 d in the model group were significantly longer than those QUESTIONNAIRE (PDQ-8): RESULTS FROM
in the EA group (P<0.05); the rotation lasting time at 3 d, 7 d AMERICA, CANADA, JAPAN, ITALY AND SPAIN.
and 14 d in the model group and the EA group were JENKINSON C, FITZPATRICK R. parkinsonism relat
gradually shortened (P<0.01, or P<0.05), but at 7 d, 14 d in disord. 2007;13(1):22-8 (eng).
the model group were significantly longer than those in the OBJECTIVE: The purpose of this study was to evaluate the
EA group (P<0.05); the DA neuron apoptosis number in the psychometric properties of a short form health survey, the
model group were significantly higher than those in the Parkinson's Disease Questionnaire (PDQ-8), cross-culturally,
normal group, with a very significant difference (P<0.01); the by comparing results gained from this instrument to the
apoptosis number in the EA group tended to decrease, at 7 d original longer form instrument-the PDQ-39. DESIGN: Data
and 14 d were significantly lower than that in the model are from the Global Parkinson's Disease Survey.
group (P<0.05). CONCLUSION: Electroacupuncture can OUTCOMES: The 8-item Parkinson's Disease Questionnaire
effectively prevent from injury of dopaminergic neurons in Single Index Score (PDQ-8-SI). In this study, we evaluate
the substantia nigra of the rat with Parkinson's disease. response rate, scaling assumptions, and data quality, in terms
of comparability of results with the parent form from which
268- gera: 145546/di/ra the PDQ-8 was derived, of the instrument in the USA,
[THERAPEUTIC EFFECT OF SCALP Canada, Spain, Italy and Japan. RESULTS: The PDQ-8 was
ELECTROACUPUNCTURE ON PARKINSON found to produce results that were very similar to the parent
DISEASE]. JIANG XM, HUANG Y, ZHUO Y, GAO YP. form across all five countries. However, it should be borne in
nan fang yi ke da xue xue bao. 2006;26(1):114-6 (chi). mind that the PDQ-8 was nested within the PDQ-39, and
OBJECTIVE: To observe the therapeutic effect of scalp results may be influenced by this. CONCLUSIONS: Results
electroacupuncture on Parkinson disease (PD) of grade 1.5- suggest that the PDQ-8 is a valid and reliable measure that
3.0 on Hoehn-Yahr scale. METHODS: Thirty patients with can be appropriately
Parkinson disease were randomized equally into the
treatment group and control group. Patients in the treatment 271- gera: 145561/di/re
group were treated by scalp eletroacupuncture at the ACUPUNCTURE FOR PSYCHOGENIC MOVEMENT
contralateral points of MS6, MS4, MS8, MS9 and MS14 in DISORDERS: TREATMENT OR DIAGNOSTIC
cases of unilateral lesions or at the bilateral points for TOOL?. VAN NUENEN BF, WOHLGEMUTH M, WONG
bilateral lesions, with also medication with Madopar. The CHUNG RE, ABDO WF, BLOEM BR. mov disord.
patients in the control group were given Madopar only. The 2007;may 7:x (eng).
scores of Webster scale and the motor function of United Psychogenic movement disorders are common in everyday
Parkinson's Disease Rating Scale (UPDRS) were used to for neurological practice, comprising up to 25% of the patient
assessment before and after the therapeutic course (6 weeks). population in movement disorders clinics. The diagnosis is
RESULTS: Tremor, rigidity and bradykinesia were obviously often difficult, as is illustrated by the high proportion of
improved in both the groups (P<0.05). The difference in the patients with an organic neurological disease whose
score of Webster scale was not significant between the two movement disorder is misdiagnosed as psychogenic. Here,
groups (P>0.05), but the treatment group showed greater we describe a woman with a longstanding and treatment-
improvement in motor functions than the control group resistant psychogenic movement disorder that responded
(P<0.05). CONCLUSION: Scalp electroacupuncture is dramatically to acupuncture. The diagnostic and therapeutic
effective and safe for merits of acupuncture are
gera 2011
24
posttest change was observed at the end of the 5-day program activity (P>0. 05); and the behavior indexes and tissue and
in all three physical-performance measures (p < .05). The form of the brain had significant improvement. Conclusion
results of this pilot evaluation suggest that Tai Chi is an Scalp catgut embedding has regulative action on anti-oxidant
appropriate physical activity for older adults with PD and enzyme system in the Parkinson's disease rats, bas significant
might also be useful as a therapeutic exercise modality for
improving and maintaining physical function. These 275- gera: 147540/di/ra
preliminary findings warrant further investigation. [PROTECTIVE EFFECT OF BAICALIN ON MOUSE
WITH PARKINSON'S DISEASE INDUCED BY MPTP].
273- gera: 147022/nd/ra CHEN X, ZHANG N, ZOU HY. chinese journal of
CHINESE HERBS AND HERBAL EXTRACTS FOR integrated traditional and western medicine.
NEUROPROTECTION OF DOPAMINERGIC 2007;27(11):1010 (chi).
NEURONS AND POTENTIAL THERAPEUTIC OBJECTIVE: To observe the protective effect of baicalin on
TREATMENT OF PARKINSON'S DISEASE. CHEN mouse with Parkinson's disease induced by 1-methyl- 4-
LW, WANG YQ, WEI LC, SHI M, CHAN YS. cns neurol phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). METHODS:
disord drug targets. 2007;6(4):273-281 (eng). The mouse model of Parkinson's disease was established by
Parkinson's disease (PD) is a common and debilitating intraperitoneal injection of MPTP at the daily dose of 30
degenerative disease resulting from massive degenerative mg/kg for 3 days to the aged (ten months old) C57BL mouse.
loss of dopamine neurons, particularly in the substantia nigra. And to the model mice in the tested group, baicalin (100
The most classic therapy for PD is levodopa administration, mg/kg) was given via gastric perfusion per day for 15 days.
but the efficacy of levodopa treatment declines as the disease The motor function of limbs in mice was tested through
progresses. The neuroprotective strategies to rescue nigral hanging and swimming tests; the dopamine content of
dopamine neurons from progressive death are currently being striatum was measured by HPLC; and the contents of
explored, and among them, the Chinese herbs and herbal malondialdehyde (MDA), glutathione (GSH) and glutathione
extracts have shown potential clinical benefit in attenuating peroxidase (GSH-Px) in the brain tissue were measured by
the progression of PD in human beings. Growing studies spectrophotography. Besides, the freezing section of mouse
have indicated that a range of Chinese herbs or herbal brain was made through immunohistochemical stain with
extracts such as green tea polyphenols or catechins, panax tyrosine hydroxylase (TH) to determine the condition of
ginseng and ginsenoside, ginkgo biloba and EGb 761, dopaminergic neuron damage in mesencephalon. RESULTS:
polygonum, triptolide from tripterygium wilfordii hook, (1) The decreased score in the hanging test and swimming
polysaccharides from the flowers of nerium indicum, oil from test, the reduced DA contents of striatum and lessening of TH
ganoderma lucidum spores, huperzine and stepholidine are positive neurons in substantial nigra illustrated the model of
able to attenuate degeneration of dopamine neurons and Parkinson's disease was successfully established. (2)
sympotoms caused by the neurotoxins 1-methyl-4-phenyl- Medication of baicalin could prevent the loss of TH positive
1,2,3,6-tetrahydropyridine (MPTP) and 6- hydroxydopamine neurons in substantial nigra and the decrease of dopamine
(6-OHDA) in vitro and in vivo conditions. In addition, content of striatum in Parkinson mouse, and significantly
accumulating data have suggested that Chinese herbs or raise the content of GSH in the brain, but MPTP induced
herbal extracts may promote neuronal survival and neurite motor dysfunction in model mouse was not significantly
growth, and facilitate functional recovery of brain injures by improved by a short-time medication. CONCLUSION: The
invoking distinct mechanisms that are related to their preventive medication of baicalin shows a protective effect
neuroprotective roles as the antioxidants, dopamine on C57 BL mouse with Parkinson's disease induced by
transporter inhibitor, monoamine oxidase inhibitor, free MPTP.
radical scavengers, chelators of harmful metal ions,
modulating cell survival genes and signaling, anti-apoptosis 276- gera: 147601/di/ra
activity, and even improving brain blood circulation. New DISCUSSION ON THE INFLUENCING FACTS OF
pharmaceutical strategies against PD will hopefully be ACUPUNCTURE TREATING INSOMNIA. SU QIU- JU.
discovered by understanding the various active entities and journal of clinical acupuncture and moxibustion.
valuable combinations that contribute to the biological effects 2007;23(10):51 (chi).
of Chinese herbs and
277- gera: 147913/di/ra
274- gera: 147090/di/ra EFFECTS OF ELECTRO-SCALP ACUPUNCTURE
EFFECTS OF SCALP CATGUT EMBEDDING ON ON CEREBRAL DOPAMINE TRANSPORTER IN
SOD, NO, MDA IN THE RAT WITH PARKINSON'S PATIENTS WITH PARKINSONS DISEASE
DISEASE. XIE XIAO-XIA, KOU SUO-TANG, PU ZHI- (ABSTRACT). HUANG YONG ET AL. journal of
HONG , ET AL. chinese acupuncture and moxibustion. alternative and complementary medicine. 2007;13(8):894
2007;27(10):753 (chi). (eng).
Objective To explore the mechanism of scalp catgut
embedding for treatment of Parkinson's disease. Methods 278- gera: 152038/di/ra
Parkinson's disease model rats were prepared, and randomly EFFECTIVE POINTS TO TREAT PARKINSON'S
divided into a model group, scalp acupuncture group, DISEASE AND THE POSSIBLE MECHANISM. YU X.
medication group, with a control group set up. The scalp international journal of clinical acupuncture.
acupuncture group were treated with catgut embedding at 2007;16(1):43 (eng).
"the chorea-trembling conroued area" lateral to "Baihui" (GV
20) and the medication group with intragastric perfusion of 279- gera: 148713/di/ra
L-dopa suspension. After treatment for 30 days, behavior [PROTECTIVE EFFECTS OF CISTANCHE TOTAL
indexes were investigated and malondialdehyde (MDA) and GLYCOSIDES ON DOPAMINERGIC NEURON IN
nitric oxide (NO) contents and superoxide dismutase (SOD) SUBSTANTIA NIGRA OF MODEL MICE OF
activity in the brain were detected. Results MDA content in PARKINSON'S DISEASE]. LI WEN-WEI, YANG RU,
the brain of the model 'rats were significantly decreased (P<0. CAI DING-FANG, ET AL. chinese journal of integrated
01), NO level significantly increased (P<0. 05),by scalp traditional and western medicine. 2008;28(3):248 (chi).
catgut embedding, with no significant change of SOD Objective To investigate the protective effects of cistanche
gera 2011
25
total glycosides ( CTG) on dopaminergic neuron in substantia grading 2-3 need medical treatment. Late stage: The patients
nigra (SN) of model mice of Parkinson's disease (PD) . have severe clinical symptoms of Parkinson's disease, and
Methods Experimental mice were randomly divided into 5 Levodopa preparation is insufficient for them to maintain
groups, the normal control group, the model group, the high their daily life; and their modified Hoehn & Yahr grading is
(400 mg/kg) , moderate (200 mg/kg) and low (100 mg/kg) 4-5. The three treating methods are: TCM medical treatment
dose CTG groups. Mouse model of chronic PD was induced adopted at the early stage; the combined treatment of Chinese
by peritoneal injection of MPTP (1-methyl-4-phenyl-1 , 2 , 3 and western medicine at the mid stage; and
, 6-tetrahydropyridine) 30 mg/kg for 5 successive days.
Climbing test was used to estimate the neurobehavior of mice 282- gera: 149208/di/ra
on the 7th and 14th day (D7 and D14) after initiating MPTP FURTHER DISCUSSION ON THE THREE METHODS
injection ; meantime , quantitative immunohistochemistry FOR THE STAGE-TREATMENT OF PARKINSON'S
was conducted to detect the number of dopaminergic neuron DISEASE 1 T-R C. ZHAO GUOHUA. journal of
in SN and expression of tyrosine hydroxylase (TH) in traditional chinese medicine. 2008;28(1): (eng).
striatum. Results The average time of climbing in the high
dose CTG group on D7 and D14 was significantly shorter 283- gera: 149866/di/re
than that in the model group (P <0. 01) . The mean optic EFFECTIVENESS OF ACUPUNCTURE FOR
density (OD) of TH in striatum was higher in the three CTG PARKINSON'S DISEASE: A SYSTEMATIC REVIEW.
groups than that in the model group on D7 (P < 0. 01) ; but LEE MS, SHIN BC, KONG JC, ERNST E. mov disord.
on D14 , significance only showed in the high and moderate 2008;jul 11:x (eng).
dose CTG groups (P <0. 01) . Moreover, the MPTP induced The objective of this review is to assess the clinical evidence
decrease of TH positive neuron could be antagonized by for or against acupuncture as a treatment for Parkinson's
CTG , but significant difference only showed between the disease (PD). We searched the literature using 17 databases
high dose CTG group and the model group at the two time from their inception to September 2007 (searched again 3rd
points of observation (P <0. 05) . Conclusion CTG could January 2008), without language restrictions. We included all
improve the neurobehavior of PD model mice significantly, randomized clinical trials (RCTs) regardless of their design.
and inhibit the decrease of nigral dopaminergic neurons and Methodological quality was assessed using the Jadad score.
TH expression in striatum. Eleven RCTs met all inclusion criteria. Three RCTs assessed
the effectiveness of acupuncture on Unified Parkinson's
280- gera: 148761/di/re Disease Rating Scale (UPDRS) compared with placebo
THERAPEUTIC STRATEGIES FOR PARKINSON'S acupuncture. A meta-analysis of these studies showed no
DISEASE: THE ANCIENT MEETS THE FUTURE- significant effect (n = 96, WMD, 5.7; 95% CI -2.8 to 14.2, P
TRADITIONAL CHINESE HERBAL MEDICINE, = 0.19, heterogeneity: tau(2) = 0, chi(2) = 0.97, P = 0.62, I(2)
ELECTROACUPUNCTURE, GENE THERAPY AND = 0%). Another six RCTs compared acupuncture plus
STEM CELLS. WANG X, LIANG XB, LI FQ, ZHOU HF, conventional drugs on improvement of symptoms of PD with
LIU XY, WANG JJ, WANG XM. neurochem res. 2008;apr drugs only. A meta-analysis of two of these studies suggested
11:x (eng). a positive effect of scalp acupuncture (n = 106, RR, 1.46,
In China, it has been estimated that there are more than 2.0 95% CI = 1.15 to 1.87, P = 0.002; heterogeneity: tau(2) =
million people suffering from Parkinson's disease, which is 0.00, chi(2) = 1.14, P = 0.29, I(2) = 12%). Two further RCTs
currently becoming one of the most common chronic tested acupuncture versus no treatment. The meta-analysis of
neurodegenerative disorders during recent years. For many these studies also suggested beneficial effects of acupuncture.
years, scientists have struggled to find new therapeutic The results of the latter two types of RCTs fail to adequately
approaches for this disease. Since 1994, our research group control for nonspecific effects. In conclusion, the evidence
led by Drs. Ji-Sheng Han and Xiao-Min Wang of for the effectiveness of acupuncture for treating PD is not
Neuroscience Research Institute, Peking University has convincing. The number and quality of trials as well as their
developed several prospective treatment strategies for the total sample size are too low to draw any firm conclusion.
disease. These studies cover the traditional Chinese Further rigorous trials are warranted. (c) 2008 Movement
medicine-herbal formula or acupuncture, and modern Disorder Society.
technologies such as gene therapy or stem cell replacement
therapy, and have achieved some original results. It hopes 284- gera: 149982/di/ra
that these data may be beneficial for the research EFFICACY AND SAFETY OF ACUPUNCTURE FOR
development and for the future clinical utility for treatment of IDIOPATHIC PARKINSON'S DISEASE: A
Parkinson's disease. SYSTEMATIC REVIEW. YUEN CHI LAM, WAN FUNG
KUM, SIVA SUNDARA KUMAR DURAIRAJAN, JIA
281- gera: 148847/di/ra HONG LU, SUI CHEUNG MAN, MIN XU, XIAO FEI
FURTHER DISCUSSION ON THE THREE METHODS ZHANG, XIAN ZHANG HUANG, MIN LI. journal of
FOR THE STAGE-TREATMENT OF PARKINSON'S alternative and complementary medicine. 2008;14(6):663
DISEASE. ZHAO G. journal of traditional chinese (eng).
medicine. 2008;28(1):39 (eng). Objectives: To assess the efficacy and safety of acupuncture
Based on the long-term clinical practice and scientific therapy (monotherapy or adjuvant therapy), compared with
researches on the three methods for the stage-treatment of placebo, conventional interventions, or no treatment in
Parkinson's disease put forward by the author in the early treating patients with idiopathic Parkinson's disease
years, this essay further discusses the division of the three (IPD).Data sources: International electronic database: (1) The
stages of Parkinson's disease. Early stage: Appearance of the Cochrane Controlled Trials Register, (2) Academic Search
early symptoms and signs of Parkinson's disease, but short in Premier, (3) ACP Medicine, Alternative Medicine, (4)
duration and mild in severity, which do not affect the social CINAHL, (5) EBM Reviews, (6) EMBASE, (7) MEDLINE,
communications, daily life and work of the patient; and their (8) OLD MEDLINE, (9) ProQuest Medical Library. Chinese
modified Hoehn & Yahr grading is 1.0-1.5. Mid stage: With electronic databases searched included: (1) VIP, (2) CJN, (3)
the symptoms and signs of Parkinson's disease getting worse CBM disk, (4) China Medical Academic Conference. Hand
and affecting the social communications, daily life and work searching was conducted on all appropriate journals.
of the patient, those who have their modified Hoehn & Yahr Reference lists of relevant trials and reviews were also
gera 2011
26
searched to identify additional studies.Selection criteria: All those with ALZ. RESEARCH EVIDENCE: Practice of TCC
randomized controlled trials (RCTs) of any duration is widely advocated as an exercise option in PD; however,
comparing monotherapy and adjuvant acupuncture therapy little validating research exists. Even less is known about
with placebo or no intervention were included. Data feasibility of applications of TCC for individuals with ALZ.
collection and analysis: Data were abstracted independently CLINICAL IMPRESSIONS: The slow, rhythmic pace of
by Y. C. Lam and S. C. Man onto standardized forms, and functionally based exercises, internal organ stimulation,
disagreements were resolved by discussion.Main results: Ten flexibility maintenance, balance-training effects, and general
(10) trials were included, each using a different set of health benefits of TCC and Tai Chi-like exercise practice
acupoints and manipulation of needles. None of them have clinical relevance for both conditions. Falls prevention,
reported the concealment of allocation. Only two mentioned tremor reduction and motor control may be of most
the number of dropouts. Two (2) used a nonblind method importance in management of PD. Behavioral and general
while others did not mention their blinding methods. Nine (9) health benefits as well as slowing of functional and cognitive
studies claimed a statistically significant positive effect from decline are considerations with ALZ.
acupuncture as compared with their control; only one RECOMMENDATIONS: Strategies of exercise adaptation
indicated that there were no statistically significant include use of Tai Chi-like exercise for individuals with ALZ
differences for all variables measured. Only 2 studies and those in middle or late stages of PD as well as providing
described details about adverse events.Conclusions: There is instructional resources and training for caregivers and
evidence indicating the potential effectiveness of acupuncture exercise aides to facilitate practice as a part of daily life.
for treating IPD. The results were limited by the
methodological flaws, unknowns in concealment of 287- gera: 150853/di/ra
allocation, number of dropouts, and blinding methods in the [OBSERVATION ON THERAPEUTIC EFFECT OF
studies. Large, well- designed, placebo-controlled RCTs with ACUPUNCTURE COMBINED WITH MEDICINE ON
rigorous methods of randomization and adequately concealed PARKINSON DISEASE]. CHANG XH, ZHANG LZ, LI
allocation, YJ. chinese acupuncture and moxibustion. 2008;28(9):645
(eng).
285- gera: 150120/nd/ra OBJECTIVE: To observe therapeutic effect of acupuncture
DOPAMINE TRANSPORTER INHIBITORY AND on Parkinson disease (PD). METHODS: Sixty cases of PD
ANTIPARKINSONIAN EFFECT OF COMMON were randomly divided into 2 groups, an acupuncture plus
FLOWERING QUINCE EXTRACT. ZHAO G, JIANG medication group and a medication group, 30 cases in each
ZH, ZHENG XW, ZANG SY, GUO LH. pharmacol group. The acupuncture plus medication group were treated
biochem behav. 2008;90(3):363-71 (eng). with acupuncture at Shenting (GV 24), Baihui (GV 20),
Common flowering quince (FQ) is the fruit of Chaenomeles Sishencong (EX-HN 1), etc. and oral administration of
speciosa (Sweet) Nakai. FQ-containing cocktails have been Madopa, and the medication group only with Madopa. Their
applied to the treatment of neuralgia, migraine, and therapeutic effect and scores of Parkinson disease function
depression in traditional Chinese medicine. The present study rating scale (modified UPDRS) were compared. RESULTS:
assessed whether FQ is effective in dopamine transporter The total improvement rate of 80.0% in the acupuncture plus
(DAT) regulation and antiparkinsonism by utilizing in vitro medication group was significantly higher than 60.0% in the
and in vivo assays, respectively. FQ at concentrations of 1- medication group (P < 0.05); the decrease of cumulative
1000 microg/ml concentration- dependently inhibited score of UPDRS in the acupuncture plus medication group
dopamine uptake by Chinese hamster ovary (CHO) cells was better than that in the medication group (P < 0.05).
stably expressing DAT (D8 cells) and by synaptosomes. FQ CONCLUSION:
had a slight inhibitory action on norepinephrine uptake by
CHO cells expressing the norepinephrine transporter and no 288- gera: 150894/di/ra
inhibitory effect on gamma-aminobutyric acid (GABA) CLINICAL EXPERIENCE OF ACUPUNCTURE
uptake by CHO cells expressing GABA transporter-1 or TREATING PARKINSONISM BY PROFESSOR
serotonin uptake by the serotonin transporter. A viability CHENG WEIPING. GONG YU HUA, CHI YAN RU,
assay showed that FQ mitigated 1-methyl-4- CHENG WEIR PING. journal of clinical acupuncture and
phenylpyridinium-induced toxicity in D8 cells. Furthermore, moxibustion. 2008;24(9):54 (chi).
in behavioral studies, FQ alleviated rotational behavior in 6-
hydroxydopamine-treated rats and improved deficits in 289- gera: 150993/di/re
endurance performance in 1-methyl-4-phenyl-1,2,3,6- PROTEOMIC ANALYSIS OF THE
tetrahydropyridine (MPTP)-treated mice. Furthermore, NEUROPROTECTIVE MECHANISMS OF
immunohistochemistry revealed that FQ markedly reduced ACUPUNCTURE TREATMENT IN A PARKINSON'S
the loss of tyrosine hydroxylase-positive neurons in the DISEASE MOUSE MODEL. JEON S, KIM YJ, KIM ST,
substantia nigra in MPTP-treated mice. In summary, FQ is a MOON W, CHAE Y, KANG M, CHUNG MY, LEE H,
selective, potent DAT inhibitor and has antiparkinsonian-like HONG MS, CHUNG JH, JOH TH, LEE H, PARK HJ.
effects that are mediated possibly by DAT suppression. FQ proteomics. 2008;oct 22:x (eng).
has the potential to be further developed for Parkinson's Acupuncture is frequently used as an alternative therapy for
disease treatment. Parkinson's disease (PD), and it attenuates dopaminergic
(DA) neurodegeneration in the substantia nigra (SN) in PD
286- gera: 150278/di/ra animal models. Using proteomic analysis, we investigated
TAI CHI CHUAN IN THE MANAGEMENT OF whether acupuncture alters protein expression in the SN to
PARKINSON'S DISEASE AND ALZHEIMER'S favor attenuation of neuronal degeneration. In C57BL/6 mice
DISEASE. KLEIN PJ. med sport sci. 2008;52:173-81 (eng). treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
BACKGROUND: Parkinson's disease (PD) and Alzheimer's (MPTP, 30 mg/kg/day), intraperitoneal (i.p.) for 5 days, 2 or
disease (ALZ) represent later-life onset neurodegenerative 100 Hz electroacupuncture (EA) was applied at the effective
disorders that gradually rob those afflicted of their quality of and specific acupoint, GB34, once a day for 12 consecutive
life. PURPOSE: This chapter offers practice-based days from the first MPTP treatment. Both treatments in
recommendations on how instruction and practice of Tai Chi MPTP mice led to restoration of behavioral impairment and
Chuan (TCC) can be adapted for individuals with PD and rescued tyrosine hydroxylase (TH)-positive DA
gera 2011
27
neurodegeneration. Using peptide fingerprinting MS, we envisage dans larsenal thrapeutique de cette maladie
identified changes in 22 proteins in the SN following MPTP neurodgnrative. En effet, mme si les tremblements
treatment, and nine of these proteins were normalized by EA. persistent aprs cinq mois de traitement, on constate une trs
They were involved in cell death regulation, inflammation, or nette amlioration des activits de la vie quotidienne avec
restoration from damage. The levels of cyclophilin A disparition de la constipation, amlioration de linsomnie et
(CypA), which is a neuroprotective agent, were unchanged de lanxit, ce que confirment les essais comparatifs
by MPTP treatment but were increased in MPTP-EA mice. randomiss retrouvs dans la littrature. Les mcanismes
These results suggest that acupoint GB34-specific EA neurophysiologiques de cette action commencent tre
changes protein expression profiles in the SN in favor of DA connus. Ils rsultent dune neuroprotection entranant une
neuronal survival in MPTP-treated mice, and that EA inhibition de la microglie avec suppression des rponses
treatment may be an effective therapy for PD patients. inflammatoires (TNF-a, interleukine-1bta, cyclooxygnase-
2), action neurotrophique du BDNF (Brain-derived
290- gera: 151233/di/ra neurotrophic factor) et du GDNF (Glial cell line-
FIFTY CASES OF PARKINSON'S DISEASE
TREATED BY ACUPUNCTURE COMBINED WITH 293- gera: 153494/di/ra
MADOPAR. REN XM. journal of traditional chinese IMPACTS OF PENETRATION THERAPY WITH
medicine. 2008;28(4):255-7 (eng). HEAD ELECTRICAL ACUPUNCTURE ON
OBJECTIVE: To search for an effective therapy for treating PROLIFERATION OF NEURAL STEM CELLS IN
motor disorder due to Parkinson's disease (PD). METHODS: SUBSTANTIA NIGRA OF RAT MODEL OF
Fifty cases in a treatment group were treated by acupuncture PARKINSON'S DISEASE. WANG Shun, QI Xiu-jie,HAN
combined with madopar, and 30 cases in a control group Di,. world journal of acupuncture-moxibustion.
treated by madopar only. RESULTS: A total effective rate of 2008;18(4):23 (eng).
92% was achieved with obvious alleviation of motor disorder To probe into the function mechanism of penetration therapy
in the treatment group, which was significantly higher than with head electrical acupuncture on Parkinson's disease.
that in the control group (P<0.05). CONCLUSION: Methods Microinjection of 6-hydroxydopamin (6-OHDA) on
Acupuncture can enhance therapeutic effects of western the left corpus striatum was adopted to prepare rotation
medicine and lessen the dose of model of Parkinson's disease in rat. Penetration therapy with
head electrical acupuncture was administered in treatment.
291- gera: 152522/di/ra Normal group, sham-operation group, model group and
PROTEOMIC ANALYSIS OF THE penetration therapy group were set up.
NEUROPROTECTIVE MECHANISMS OF ~lmmunohistochemical (IHC) method was used to test the
ACUPUNCTURE TREATMENT IN A PARKINSON'S morphology and count of positive cell of tyrosine
DISEASE MOUSE MODEL. JEON S, KIM YJ, KIM ST, hydroxylase (TH). @RT-PCR technology was used to detect
MOON W, CHAE Y, KANG M, CHUNG MY, LEE H, the expression of nestin mRNA of neural stem cell (NSC).
HONG MS, CHUNG JH, JOH TH, LEE H, PARK HJ.. Results acornpared with model group, in penetration therapy
proteomics. 2008;8(22):4822-32 (en). group, the expressions of TH-positive neurons in immune
Acupuncture is frequently used as an alternative therapy for response were increased in areal density (AD), numerical
Parkinson's disease (PD), and it attenuates dopaminergic density (ND) and integrating optic density ( P<O. 05).
(DA) neurodegeneration in the substantia nigra (SN) in PD OCompared with model group, in penetration therapy group,
animal models. Using proteomic analysis, we investigated the expression of nestin mRNA was increased (P<O. 05).
whether acupuncture alters protein expression in the SN to Conclusion Penetration therapy with head electrical
favor attenuation of neuronal degeneration. In C57BL/6 mice acupuncture promotes the proliferation of endogenous neural
treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine stem cells in substantia nigra of rat model of Parkinson's
(MPTP, 30 mg/kg/day), intraperitoneal (i.p.) for 5 days, 2 or disease.
100 Hz electroacupuncture (EA) was applied at the effective
and specific acupoint, GB34, once a day for 12 consecutive 294- gera: 152246/di/re
days from the first MPTP treatment. Both treatments in QIGONG FOR MOVEMENT DISORDERS : A
MPTP mice led to restoration of behavioral impairment and SYSTEMATIC REVIEW, LEE MS, ERNST E. movement
rescued tyrosine hydroxylase (TH)-positive DA disorders. 2009;24(2):301-3 (eng).
neurodegeneration. Using peptide fingerprinting MS, we
identified changes in 22 proteins in the SN following MPTP 295- gera: 152512/co/ra
treatment, and nine of these proteins were normalized by EA. ACUPUNCTURE INHIBITS FERRIC IRON
They were involved in cell death regulation, inflammation, or DEPOSITION AND FERRITIN-HEAVY CHAIN
restoration from damage. The levels of cyclophilin A REDUCTION IN AN MPTP- INDUCED
(CypA), which is a neuroprotective agent, were unchanged PARKINSONISM MODEL. CHOI YG, PARK JH, LIM S.
by MPTP treatment but were increased in MPTP-EA mice. neurosci lett. 2009;450(2):92-6 (eng).
These results suggest that acupoint GB34-specific EA This study investigated the effect of acupuncture on iron-
changes protein expression profiles in the SN in favor of DA related oxidative damage in a mouse model designed as a 1-
neuronal survival in MPTP-treated mice, and that EA methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced
treatment may be an effective therapy for PD patients. parkinsonism model. To generate the chronic parkinsonism
model, mice were intraperitoneally injected with MPTP
292- gera: 152963/di/ra (20mg/kg, one daily injection) for 30 days and acupuncture
A PROPOS DUN CAS CLINIQUE : INTRT DE was performed at acupoints LR3 (Taichong) and GB34
LACUPUNCTURE DANS LA MALADIE DE (Yanglingquan) at 48h intervals. Acupuncture inhibited
PARKINSON. STEPHAN JM,. acupincture & decreases in the immunoreactivities of tyrosine hydroxylase
moxibustion. 2008;7(4):322-330 (fra). (TH) and dopamine transporter (DAT) that occurred as a
Ltude dun cas clinique de maladie de Parkinson, result of MPTP neurotoxicity. The presence of ferric iron
diagnostiqu vide de yin du Foie et du Rein selon la (Fe(3+)), but not ferrous iron (Fe(2+)), was strongly
diffrenciation des syndromes (zheng) de la Mdecine increased in the substantia nigra (SN) as a result of chronic
Traditionnelle Chinoise objective que lacupuncture doit tre loading of MPTP, whereas the ferritin-heavy chain (F-H) was
gera 2011
28
significantly decreased. However, acupuncture treatment and a point-through-point therapy group. 6-()HDA was
inhibited the increase in ferric iron and the decrease in the F- injected into left striatum to made lateralization Parkinson's
H that was induced by MPTP. Additionally, treatment with disease rat model. The point-through-point therapy group was
MPTP and acupuncture caused no changes in the presence of treated with electroacupuncture at "Baihui" (GV 20 )-
ferrous iron and ferritin-light chain (F-L) as a result of the through-"Taiyang" (EX-NH 5), once each day, 6 days
treatments. The mRNA of F-H was also not affected. These constituting one course, for 2 courses, and the rats of other
results suggest that acupuncture may inhibit iron- related groups were not treated. HE staining method was used for
oxidative damage and may prevent the deleterious alteration observation of the histo-morphologic changes of the
of iron metabolism in the MPTP model. substantia nigra neurons, and RT-PCR for the expression of
tyrosine hydroxylase (TH) and dopamine transporter (DAT)
296- gera: 152695/di/ra mRNAs. RESULTS: The expressions of TH mRNA (1.22 +/-
CLINICAL OBSERVATION OF COMBINED 0. 19) and DAT mRNA (0.62-0.11) in the point-through-
ACUPUNCTURE AND HERBS IN TREATING point therapy group were significantly higher than (0.65 +/-
PARKINSON'S DISEASE. HUAN WEN-YAN. journal of 0.17) and (0.41 +/- 0.08) in the model group, respectively (all
acupuncture and tuina science. 2009;7(1):33-36 (eng). P < 0.05). As compared with the model group, the number of
neurons in the substantia nigra increased and degeneration of
297- gera: 153304/nd/re the neurons relieved in the point-through-point therapy
ALTERNATIVE APPROACHES TO EPILEPSY group. CONCLUSION: The electroacupuncture scalp point-
TREATMENT. MCELROY-COX C. curr neurol neurosci through-point therapy can increase expressions of TH mRNA
rep. 2009;9(4):313-8 (eng). and DAT mRNA in the substantia nigra in the Parkinson's
Complementary and alternative medicine (CAM) is a diverse disease model rat, and promote synthesis and reuptake of
group of health care practices and products that fall outside dopamine, hence Parkinson's disease is cured.
the realm of traditional Western medical theory and practice
and that are used to complement or replace conventional 300- gera: 154295/di/ra
medical therapies. The use of CAM has increased over the [ EXPERIMENTAL STUDY ON TREATING
past two decades, and surveys have shown that up to 44% of PARKINSEN'S DISEASE RATS BY
patients with epilepsy are using some form of CAM ELECTROACUPUNCTURE COMBINED WITH
treatment. This article reviews the CAM modalities of QUFENGZHIDONG CAPSULE]. LI Y. journal of
meditation, yoga, relaxation techniques, biofeedback, clinical acupuncture and moxibustion. 2009;25(7):50
nutritional and herbal supplements, dietary measures, (chi0).
chiropractic care, acupuncture, Reiki, and homeopathy and
what is known about their potential 301- gera: 154749/di/ra
[STUDY ON THE MECHANISM OF
298- gera: 153587/nd/re ELECTROACUPUNCTURE SCALP POINT
ELECTRO-ACUPUNCTURE STIMULATION PENETRATION THERAPY IN ACTION ON
IMPROVES MOTOR DISORDERS IN APOPTOSIS IN THE PARKINSON'S DISEASE RAT
PARKINSONIAN RATS. JIA J, SUN Z, LI B, PAN Y, MODEL]. Wang S, Jiang H, Qu L.. chinese acupuncture
WANG H, WANG X, YU F, LIU L, ZHANG L, WANG X. and moxibustion. 2009;29(4):309-13 (chi).
behav brain res. 2009;JUN 20: (eng). OBJECTIVE: To explore the mechanism of
Electro-acupuncture (EA) is believed to be effective for electroacupuncture scalp point penetration therapy in
alleviating motor symptoms in patients with Parkinson's treatment of the Parkinson's disease (PD). METHODS: Forty
disease. In a rat hemiparkinsonian model induced by Wistar rats were randomly divided into a normal group, a
unilateral transection of the medial forebrain bundle (MFB), sham-operation group, a model group and an
the effects of EA stimulation were investigated. EA electroacupuncture (EA) group. 6-OHDA was injected into
stimulation at a high frequency (100Hz) significantly reduced the left striatum to make lateralization PD rat model.
apomorphine-induced rotational behavior. Tyrosine Acupuncture at "Baihui" (GV 20)-through-"Taiyang" (EX-
hydroxylase immunohistochemical staining revealed that EA HN 5), once each day, 6 days constituting one course.
at 100Hz protected axotomized dopaminergic neurons from Immunohistochemical method was used to observe the facio-
degeneration in the substantia nigra (SN). Moreover, high density and the integral optical density of brain-derived
frequency EA reversed the axotomy-induced decrease in neurotrophic factor (BDNF) in the left substantia nigra, and
substance P content and increase in glutamate decarboxylase- TUNEL method was used to observe the apoptotic amount,
67 (GAD 67) mRNA level in the midbrain; however, it did and high performance liquid chromatography was used to
not affect the axotomy-induced increase in enkephalin observe DA contents of the left striatum in each
content in the globus pallidus. These results suggest that the group.RESULTS: As compared with the model group, in the
effects of high frequency EA on motor symptoms of acupuncture group, the facio-density and the integral optical
parkinsonian rats may involve restoration of the homeostasis density in the left substantia nigra increased significantly (P <
of dopaminergic transmission in the 0.05), the amount of apoptosis decreased significantly (P <
0.05), and the content of striatum DA increased significantly
299- gera: 153689/di/ra (P < 0.05).CONCLUSION: EA scalp point-through-point
[EFFECT OF ELECTROACUPUNCTURE SCALP therapy may enhance BDNF protein expression level in the
POINT-THROUGH-POINT THERAPY ON THE substantia nigra to decrease the amount of apoptosis in the
EXPRESSION OF TYROSINE HYDROXYLASE AND PD model rat.
DOPAMINE TRANSPORTER MRNAS IN
SUBSTANTIA NIGRA OF PARKINSON'S DISEASE 302- gera: 154797/di/ra
MODEL RATS]. WANG S, QI XJ, HAN D. chinese [EFFECT OF ELECTROACUPUNCTURE SCALP
acupuncture and moxibustion. 2009;29(5):391-4 (chi). POINT-THROUGH-POINT THERAPY ON THE
To explore the mechanism of electroacupuncture scalp point- EXPRESSION OF TYROSINE HYDROXYLASE AND
through-point therapy in the treatment of Parkinson's disease. DOPAMINE TRANSPORTER MRNAS IN
METHODS: Thirty-six Wistar rats were randomly divided SUBSTANTIA NIGRA OF PARKINSON'S DISEASE
into a normal group, a sham-operation group, a model group MODEL RATS]. WANG S, QI XJ, HAN D.. chinese
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acupuncture and moxibustion. 2009;29(5):391-4 (chi). Wistar rats were randomly divided into a normal group, a
OBJECTIVE: To explore the mechanism of sham-operation group, a model group and an
electroacupuncture scalp point-through-point therapy in the electroacupuncture (EA) group. 6-OHDA was injected into
treatment of Parkinson's disease.METHODS: Thirty-six the left striatum to make lateralization PD rat model.
Wistar rats were randomly divided into a normal group, a Acupuncture at "Baihui" (GV 20)-through-"Taiyang" (EX-
sham- operation group, a model group and a point-through- HN 5), once each day, 6 days constituting one course.
point therapy group. 6-()HDA was injected into left striatum Immunohistochemical method was used to observe the facio-
to made lateralization Parkinson's disease rat model. The density and the integral optical density of brain-derived
point-through-point therapy group was treated with neurotrophic factor (BDNF) in the left substantia nigra, and
electroacupuncture at "Baihui" (GV 20 )-through-"Taiyang" TUNEL method was used to observe the apoptotic amount,
(EX-NH 5), once each day, 6 days constituting one course, and high performance liquid chromatography was used to
for 2 courses, and the rats of other groups were not treated. observe DA contents of the left striatum in each
HE staining method was used for observation of the histo- group.RESULTS: As compared with the model group, in the
morphologic changes of the substantia nigra neurons, and acupuncture group, the facio-density and the integral optical
RT-PCR for the expression of tyrosine hydroxylase (TH) and density in the left substantia nigra increased significantly (P <
dopamine transporter (DAT) mRNAs.RESULTS: The 0.05), the amount of apoptosis decreased significantly (P <
expressions of TH mRNA (1.22 +/- 0. 19) and DAT mRNA 0.05), and the content of striatum DA increased significantly
(0.62-0.11) in the point-through-point therapy group were (P < 0.05).CONCLUSION: EA scalp point-through-point
significantly higher than (0.65 +/- 0.17) and (0.41 +/- 0.08) in therapy may enhance BDNF protein expression level in the
the model group, respectively (all P < 0.05). As compared substantia nigra to decrease the amount of apoptosis in the
with the model group, the number of neurons in the PD model rat.
substantia nigra increased and degeneration of the neurons
relieved in the point-through-point therapy 305- gera: 154924/di/ra
group.CONCLUSION: The electroacupuncture scalp point- [EFFECT OF ELECTROACUPUNCTURE SCALP
through-point therapy can increase expressions of TH mRNA POINT-THROUGH-POINT THERAPY ON THE
and DAT mRNA in the substantia nigra in the Parkinson's EXPRESSION OF TYROSINE HYDROXYLASE AND
disease model rat, and promote synthesis and reuptake of DOPAMINE TRANSPORTER MRNAS IN
dopamine, hence Parkinson's disease is cured. SUBSTANTIA NIGRA OF PARKINSON'S DISEASE
MODEL RATS]. Wang S, Qi XJ, Han D.. chinese
303- gera: 154831/di/ra acupuncture and moxibustion. 2009;29(5):391-4 (chi).
[CLINICAL STUDY ON SCALP ACUPUNCTURE OBJECTIVE: To explore the mechanism of
WITH LONG NEEDLE-RETAINED DURATION FOR electroacupuncture scalp point-through-point therapy in the
TREATMENT OF TOURETTE SYNDROME]. ZHU BC, treatment of Parkinson's disease.METHODS: Thirty-six
SHI-FEN X, SHAN YH.. chinese acupuncture and Wistar rats were randomly divided into a normal group, a
moxibustion. 2009;29(2):115-8 (chi). sham- operation group, a model group and a point-through-
OBJECTIVE: To observe therapeutic effects of different point therapy group. 6-()HDA was injected into left striatum
needle-retained durations at scalp acupoints on Tourette to made lateralization Parkinson's disease rat model. The
syndrome (TS).METHODS: Sixty-two cases of TS were point-through-point therapy group was treated with
randomly divided into an observation group and a control electroacupuncture at "Baihui" (GV 20 )-through-"Taiyang"
group, 31 cases in each group. In the observation group, the (EX-NH 5), once each day, 6 days constituting one course,
needles were retained for 2 h and in the control group, they for 2 courses, and the rats of other groups were not treated.
were retained for 30 min. The middle line of forehead, HE staining method was used for observation of the histo-
middle line of vertex and lateral line 1 of vertex were selected morphologic changes of the substantia nigra neurons, and
as main acupoints, and anterior oblique line of vertex- RT-PCR for the expression of tyrosine hydroxylase (TH) and
temporal and posterior temporal line were selected as dopamine transporter (DAT) mRNAs.RESULTS: The
adjuvant acupoints. They were treated for 2 months, once expressions of TH mRNA (1.22 +/- 0. 19) and DAT mRNA
other day. Yale Global Tic Severity Scale (YGTSS) and (0.62-0.11) in the point-through-point therapy group were
Tourette Syndrome Global Scale (TSGS) were used for significantly higher than (0.65 +/- 0.17) and (0.41 +/- 0.08) in
assessment of therapeutic effects and their therapeutic effects the model group, respectively (all P < 0.05). As compared
were compared.RESULTS: After treatment, YGTSS and with the model group, the number of neurons in the
TSGS scores had very significant changes in the two groups substantia nigra increased and degeneration of the neurons
as compared with those before treatment (both P < 0.01), relieved in the point-through-point therapy
indicating an obvious improvement in kinetic Tic and group.CONCLUSION: The electroacupuncture scalp point-
vocalizing Tic. The total effective rate was 61.3% in the through-point therapy can increase expressions of TH mRNA
observation group and 67.7% in the control group with no and DAT mRNA in the substantia nigra in the Parkinson's
significant difference between the two groups (P > 0.05). disease model rat, and promote synthesis and reuptake of
CONCLUSION: Scalp acupuncture therapy of both 2 h and dopamine, hence Parkinson's disease is cured.
0.5 h retaining needle can significantly improve symptoms of
TS patients, with a similar therapeutic effect. 306- gera: 155480/nd/re
Potential influences of complementary therapy on motor
304- gera: 154875/di/ra and non-motor complications in Parkinson's disease.
[STUDY ON THE MECHANISM OF Zesiewicz TA, Evatt ML. cns drugs. 2009;23(10):817-35
ELECTROACUPUNCTURE SCALP POINT (eng).
PENETRATION THERAPY IN ACTION ON Nearly two-thirds of patients with Parkinson's disease (PD)
APOPTOSIS IN THE PARKINSON'S DISEASE RAT use vitamins or nutritional supplements, and many more may
MODEL]. WANG S, JIANG H, QU L.. chinese use other complementary therapies, yet <50% of patients
acupuncture and moxibustion. 2009;29(4):309-13 (chi). have discussed the use of these complementary therapies with
OBJECTIVE: To explore the mechanism of a healthcare professional. Physicians should be aware of the
electroacupuncture scalp point penetration therapy in complementary therapies their patients with PD are using,
treatment of the Parkinson's disease (PD). METHODS: Forty and the possible effects of these therapies on motor and non-
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Zesiewicz TA, Evatt ML 306 , ZHAO G, JIANG ZH, ZHENG XW, ZANG SY, GUO LH
ZHANG BAOPING ET AL 186 , 285 ,
ZHANG BIAO 143 , 147 , ZHAO GUOHUA 282 ,
ZHANG HANLIANG, ZHU WEIFENG 194 , ZHAO GUOHUA TREATING 257 ,
ZHANG JF, SUN GS, ZHAO GH 229 , ZHAO HONG ET AL 111 ,
ZHANG JIANQIU ET AL 27 , ZHAO XIAO-HUI, GU CHENG-ZHI, HUANG HUAI-YU,
ZHANG JUN, ZHANG HONG-MEI, BAI 11-MIN, ET AL ET AL 178 ,
210 , ZHENG QI-WEI 90 ,
ZHANG LI ET AL 80 , 89 , ZHONG GUO DANG DAI MING YI ZHEN FANG ZHEN
ZHANG NAIZHENG ET AL 78 , SHU JI CHENG 308 ,
ZHANG QIN ET AL 127 , ZHONG MING QUAN 16 ,
ZHANG SHU-JUN FENG FU-HAI 188 , ZHOU HOUGUANG, BAO YUANCHENG, LU
ZHANG XIN GEN ET AL 44 , JIANMING, ET AL 195 ,
ZHANG XY, GAO S, ZHAO JG, CAI L, PANG JP, LU ZHOU HOUGUANG, BUO YUANCHENG 212 ,
MX 269 , ZHOU XIAO-LIN 202 ,
ZHANG YONG HUA ET AL 42 , ZHOU Y 259 ,
ZHANG YUNLING ET AL 71 , 88 , 99 , ZHU BC, SHI-FEN X, SHAN YH. 303 ,
ZHANG ZX, DONG ZH, ROMAN GC 253 , ZHU LILI 122 ,
ZHAO BINGXIANG, ET AL 225 , ZHUANG XIAOLAN ET AL 124 ,
ZHAO G 281 , ZOU YONG 258 , 262 ,
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index des sujets/ subject index 8,11 - ulcer. wound/ ulcres. plaies
(non exhaustif) * 14 ,
- /
7 , 8 , 9 , 251 , 9,03 - diabetes mellitus/ diabte
* 14 , 123 , 126 ,
1,01 - GENERAL ASPECTS AND HISTORY/
ASPECTS GENERAUX ET HISTOIRE 13,01 - INFECTIOUS DISEASES/ MALADIES
combinaison mdecine occidentale- mtc 8 , 119 , 123 , 134 INFECTIEUSES
, 162 , 209 , * 39 ,
patient 144 ,
14,01 - NEUROLOGY- PSYCHIATRY/
2,05 - meridians/ mridiens NEUROLOGIE- PSYCHIATRIE
sensation propage le long des mridiens 17 , 18 , 69 , mmoire 103 ,
2,06 - points/ points 14,03 - coma. brain injury/ coma. traumatisme crnien
huatuojiaji 3 , * 51 ,
VB34 70 ,
VG14 69 , 14,05 - epilepsy. convulsions/ epilepsie. convulsions
VG16 69 , * 126 ,
VG20 69 ,
VG26 69 , 14,06 - parkinson disease. tremor/ parkinson.
tremblement
3,02 - pathogeny. causes of diseases/ pathognie * 2 , 3 , 7 , 14 , 17 , 18 , 31 , 32 , 41 , 66 , 103 , 126 , 145 ,
vent 47 ,
14,07 - cerebrovascular diseases. hemiplegia/ accidents
4,01 - DIAGNOSIS/ DIAGNOSTIC vasculaires crbraux. * 2 , 103 , 123 , 126 ,
main 67 ,
14,09 - peripheral nerve diseases/ neuropathies
4,07 - syndromes/ syndromes priphriques
differenciation des syndromes 8 , 119 , 129 , 211 , * 14 , 41 ,
stase 47 ,
vide 39 , 47 , 14,12 - spasm and tic/ spasmes et tics
vide de yin des reins 219 , * 20 ,
yang 47 ,
yin 39 , 14,13 - insomnia. sleep disorders/ insomnie. troubles du
sommeil
5,03 - acupuncture/ acupuncture * 126 , 126 ,
sance d'acupuncture 69 ,
14,14 - psychiatry/ psychiatrie
5,04 - long needle/ aiguille longue * 103 , 126 ,
* 3 ,
16,03 - vertigo/ vertiges
5,09 - moxibustion/ moxibustion * 41 ,
* 109 ,
18,14 - lombar spine/ rachis lombaire
5,11 - nose, face, eye, hand and foot acupuncture/ * 126 ,
rhinofacio, manopodo, craniopuncture
* 3 , 22,04 - enuresis. urinary incontinence. urinary
craniopuncture 2 , 3 , 4 , 41 , 59 , 70 , 76 , 83 , 126 , 150 , retention/ nuresie. incontinence et rtention d'urine
172 , 208 , 252 , 293 , 301 , 302 , 303 , 304 , 305 , * 2 ,
nuresie 2 ,
5,12 - electro-acupuncture/ electro-acupuncture
* 14 , 54 , 68 , 172 , 252 , 301 , 304 , 23,07 - gerontology/ grontologie
* 42 , 57 ,
5,16 - qi gong. massages/ qi gong. massages
* 1 , 23,11 - pediatrics/ pdiatrie
massage 1 , 92 , 100 , * 16 , 34 , 110 , 205 , 303 ,
qi gong 16 , 35 , 36 , 64 ,
24,07 - / animaux de laboratoire
5,20 - tcm and alternative medicine/ mtc et mdecines rat 128 , 142 , 199 , 293 , 301 , 302 , 304 , 305 , 309 ,
douces souris 210 , 235 , 275 , 289 ,
homeopathie 39 ,
25,02 - afferent pathways/ voies affrentes
7,04 - arrhythmia/ troubles du rythme * 18 ,
* 54 ,
26,02 - prescriptions/ prescriptions
7,05 - hypertension/ hypertension * 42 , 43 , 48 ,
* 2 ,
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