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Eastern Intermediate High School Name:_________________________

Honors Biology Mod:______ Date:_______________

Unit 12 – The Central Dogma of Biology - DNA


Quick Quiz – DNA Discovery. Structure and Function

PART 1

Directions: Use the answer choices in the bank to fill in the blanks for each sentence below.
Write the answers in the spaces below. Each blank space is worth ½ point. Total points = 8.

Radioactive Markers Thymine Nitrogenous Base


Guanine Phosphate Group Adenine
[C] Double Helix [A]
Transformation Cytosine [T]
James Watson Francis Crick DNA
5 Carbon Sugar [G] Alpha Helix

1. The structure of DNA was determined to be a double helix.

2. The structure of DNA was discovered by James Watson and Francis Crick

3. DNA consists of four different bases: Adenine , thymine , guanine and cytosine .

4. Griffith observed that bacteria could be changed by the exchange of a “genetic factor” from
another bacteria. He called this process transformation .

5. Hershey and Chase used radioactive markers to identify DNA as the genetic material.

6. Each nucleotide is made up of a phosphate group , five carbon sugar , and a


nitrogenous base .

7. The principle of Base Pairing explained Chargraff’s rule which states: [A] = [T] and [G] =
[C]

-OVER-

Quinn_Gavin Tuesday, March 15, 2011 12:00:05 PM ET


PART 2

Directions: Use the answer choices in the bank below to fill in the blanks for each sentence
below. Each blank space is worth ½ point. Total points = 6.

Nucleosome Two DNA Replication


Proof reading Circular Adenine
Identical DNA Ligase Histone
Plasmids Chromatin Four
DNA Polymerase RNA Complementary
Chromosome DNA Helicase Re-Writing

8. DNA in eukaryotes is often wrapped around histone proteins.

9. Most prokaryotes have a single, circular piece of DNA located in the


cytoplasm.

10. A DNA molecule plus a histone molecule is known as a (an)


nucleosome

11. Many nucleosomes together form a chromatin fiber.

12. The enzyme helicase is responsible for unzipping a DNA molecule


before DNA Replication can begin.

13. Many chromatin fibers together form a chromosome

14. The enzyme DNA polymerase reads the parent strand of DNA and
adds complementary bases (matching bases) to the new strand of DNA.

15. At the end of replication, two double strands of DNA are formed that
are both identical to the original “parent” strand.

16. DNA polymerase is also cable of proof-reading the new “daughter”


strands of DNA to prevent errors from occurring during DNA replication.

Quinn_Gavin Tuesday, March 15, 2011 12:00:05 PM ET

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